 | Goldie Hawn als Elise Elliot Atchison |
 | Bette Midler als Brenda Morelli Cushman |
 | Diane Keaton als Annie MacDuggan Paradis |
 | Maggie Smith als Gunilla Garson Goldberg |
 | Sarah Jessica Parker als Shelly Stewart |
 | Dan Hedaya als Morton Cushman |
 | Stockard Channing als Cynthia Swann Griffin |
 | Victor Garber als Bill Atchison |
 | Stephen Collins als Aaron Paradis |
 | Elizabeth Berkley als Phoebe LaVelle |
 | Marcia Gay Harden als Dr. Leslie Rosen |
 | Bronson Pinchot als Duarto Feliz |
 | Jennifer Dundas als Chris Paradis |
 | Eileen Heckart als Catherine MacDuggan |
 | Philip Bosco als Uncle Carmine Morelli |
 | Rob Reiner als Dr. Morris Packman |
 | James Naughton als Gill Griffin |
 | Ari Greenberg als Jason Cushman |
 | Ivana Trump als Ivana Trump |
 | Kathie Lee Gifford als Kathie Lee Gifford |
 | Gloria Steinem als Gloria Steinem |
 | Lea DeLaria als Elise's Fan |
 | Debra Monk als Jilted Lover |
 | Kate Burton als Woman in Bed |
 | Timothy Olyphant als Brett Artounian |
 | J.K. Simmons als Federal Marshall |
| Michele Brilliant als Young Brenda |
 | Dina Spybey-Waters als Young Elise |
 | Adria Tennor als Young Annie |
| Juliehera DeStefano als Young Cynthia |
 | J. Smith-Cameron als Miss Sullivan |
 | Mark Nelson als Eric Loest |
 | Heather Locklear als Gil's New Wife |
 | Richard Council als Security Guard |
| Robert Harling | Screenplay |
| Hugh Wilson | Director |
| Scott Rudin | Producer |
| Theoni V. Aldredge | Costume Design |
| Donald E. Thorin | Director of Photography |
| John Bloom | Editor |
| Ilene Starger | Casting |
| Ezra Swerdlow | Executive Producer |
| Peter S. Larkin | Production Design |
| Adam Schroeder | Executive Producer |
| Thomas A. Imperato | Co-Producer |
| Olivia Goldsmith | Novel |
| Bernadette Mazur | Makeup Artist |
| E. Thomas Case | Makeup Artist |
| Marilyn Carbone | Makeup Artist |
| Frances Mathias | Hairstylist |
| Richard P. Cirincione | Sound Editor |
| Ezra Swerdlow | Production Manager |
| Noah Ackerman | Associate Producer |
| Peter F. Kurland | Sound Mixer |
| Kim Miscia | Casting Assistant |
| Maurice Schell | Supervising Sound Editor |
| Eytan Mirsky | Sound Editor |
| Kenton Jakub | ADR Editor |
| Nic Ratner | Music Editor |
| Charley Beal | Art Direction |
| Jay Kessel | Assistant Sound Editor |
| Tommy Louie | Cableman |
| Jerry DeBlau | Chief Lighting Technician |
| Werner Sherer | Hairstylist |
| Craig Perry | Associate Producer |
| Nicholas Meyers | Music Editor |
| Jack Gill | Stunt Coordinator |
| Heather Neely | Associate Producer |
| Shari L. Carpenter | Script Supervisor |
| Eric Myers | Unit Publicist |
| Ron Petagna | Construction Coordinator |
| Stuart Stanley | Foley Editor |
| Tom Salvatore | Color Timer |
| Ray Angelic | Production Coordinator |
| Alan D'Angerio | Hairstylist |
| John Fundus | Boom Operator |
| Wallace G. Lane Jr. | Assistant Costume Designer |
| Marc Shaiman | Music Supervisor |
| Andrew D. Schwartz | Still Photographer |
| Joseph E. Iberti | Location Manager |
| Rob Hahn | Camera Operator |
| Angela Levin | Makeup Artist |
| Bruce Kitzmeyer | Foley Editor |
| Michael E. Steele | First Assistant Director |
| Ed Check | Assistant Art Director |
| Julie A. Bloom | Second Assistant Director |
| Leslie E. Rollins | Set Decoration |
| Lee Dichter | Sound Re-Recording Mixer |
| Tod Scott Brody | Post Production Supervisor |
| Octavio Molina | Property Master |
| Julia G. Hickman | Art Department Coordinator |
| Steven R. Hammond | Transportation Captain |
| Michael Adkins | Costume Supervisor |
| Matt Vogel | Special Effects Coordinator |
| Paul D. Kelly | Assistant Art Director |
| Patricia Birch | Choreographer |
| Antonia Van Drimmelen | Associate Editor |
| Hartsell Taylor | Costume Supervisor |
| Laura Civiello | Sound Editor |
| Tom Heilig | Transportation Co-Captain |
| Nick Vidar | Music Programmer |
| Noëlle Penraat | Negative Cutter |
| Robert Ramos | Hairstylist |
| Marc Shaiman | Original Music Composer |
| Brick Mason | Storyboard Artist |
| Lorenzo Contessa | Storyboard Artist |
| Joni Avery | Stunt Double |
| Jack Gill | Second Unit Director |
