 | Jason Segel als Tom Solomon |
 | Emily Blunt als Violet Barnes |
 | Rhys Ifans als Winton Childs |
 | Chris Pratt als Alex Eilhauer |
 | Alison Brie als Suzie Barnes |
 | Jacki Weaver als Sylvia Dickerson-Barnes |
 | Jim Piddock als George Barnes |
 | David Paymer als Pete Solomon |
 | Mimi Kennedy als Carol Solomon |
 | Mindy Kaling als Vaneetha |
 | Kevin Hart als Doug |
 | Brian Posehn als Tarquin |
 | Chris Parnell als Bill |
 | Lauren Weedman als Chef Sally |
 | Tracee Chimo als Margaret |
 | Adam Campbell als Gideon |
 | Dakota Johnson als Audrey |
 | Randall Park als Ming |
 | Jane Carr als Grandma Katherine |
 | Clement von Franckenstein als Grandpa Baba |
 | Michael Ensign als Grandpa Harold |
 | Madge Levinson als Grandma Leonora |
| Zoe Niemkiewicz als Vanessa Barnes-Eilhauer |
| Rocky Rector als Randy |
| Laurie Brown als Professor Walch |
| Nicholas Delbanco als Professor Delbanco |
| Penelope Stoller als Little Violet |
 | Chris Newman als Used Car Lot Guy |
 | Murray Miller als SF Wedding Barn Manager |
 | Eileen Grubba als Botanical Garden Manager |
| Mark Rademacher als Priest |
| Kevin Yon als Rabbi |
 | Heather Mathieson als Female Justice of the Peace |
 | Kumail Nanjiani als Pakistani Chef |
| Gina Ragnone als Ashley |
 | Stephanie Faracy als Florist |
 | Aaron Lustig als Michigan Rabbi |
 | Tim Heidecker als Negotiating Chef |
 | Molly Shannon als Onion Chef |
 | AnnaCorey als Jill Wedding Attendee (uncredited) |
| Jason Segel | Screenplay |
| Nicholas Stoller | Director |
| Nicholas Stoller | Screenplay |
| Jeanne McCarthy | Casting |
| Julie Berghoff | Production Design |
| Sophie Neudorfer | Set Decoration |
| Leesa Evans | Costume Design |
| William Kerr | Editor |
| Peck Prior | Editor |
| John B. Josselyn | Art Direction |
| Javier Aguirresarobe | Director of Photography |
| Michael Andrews | Original Music Composer |
| Richard Vane | Executive Producer |
| Judd Apatow | Producer |
| Maggie Fung | Key Makeup Artist |
| Lisa Rodgers | Post Production Supervisor |
| George H. Anderson | Supervising Sound Editor |
| Louis DiCesare | Gaffer |
| Gregg Horvath | First Assistant Camera |
| Glen Wilson | Still Photographer |
| Jessica Albertson | Key Set Costumer |
| Leo Corey Castellano | Prosthetic Makeup Artist |
| Jennifer Tremont | Hairstylist |
| Hilary Bristoll | Art Department Coordinator |
| Marc Fishman | Sound Re-Recording Mixer |
| Lee Gilmore | Sound Effects Editor |
| James Matheny | Dialogue Editor |
| Scott Zuckerberg | Rigging Grip |
| Curtis Collins | Location Manager |
| Rodney Rothman | Producer |
| Boyd Bossler | Prop Maker |
| Nicholas Stoller | Producer |
| Michael Spatola | Prop Maker |
| Keith Wandrei | Dolly Grip |
| Mitch Rosin | Assistant Editor |
| Brenda Lopez | Script Supervisor |
| Andrea Pino | Makeup Artist |
| Sean Mannion | Property Master |
| Alison Fisher | Dialogue Editor |
| Adam Kogelman | Rigging Grip |
| John Wendling | Best Boy Electric |
| Nina Paskowitz | Hair Department Head |
| Eric Rhodes | Greensman |
| Larry Kemp | ADR Supervisor |
| Seth Kleinberg | Visual Effects Producer |
| Charles John Bukey | Key Grip |
| Tim O'Dea | Gaffer |
| Brian Scott Olds | First Assistant Editor |
| Adam Jenkins | Sound Re-Recording Mixer |
| Amy Snell | Rigging Grip |
| Kenneth Marsten | First Assistant Editor |
| Douglas Womack | Construction Coordinator |
| Mike Sunga | Leadman |
| Joe Bucaro III | Stunt Coordinator |
| Jeffrey J. Dashnaw | Stunt Coordinator |
| Christopher TJ McGuire | Camera Operator |
| Carl Sealove | Music Editor |
| Scott M. Davids | Visual Effects Supervisor |
| Omar Sabeh | Lighting Technician |
| Emily Streetz | Assistant Editor |
| Tammy Fearing | ADR Editor |
| Mark Karavite | Steadicam Operator |
| Cynthia Bond | Tailor |
| Ariel Gold | Costume Supervisor |
| Jonathan Karp | Music Editor |
| Emilie Cockels | Hairstylist |
| Kris Ravetto | Makeup Artist |
| Michael J. Moore | First Assistant Director |
| Sean T. Kelly | Key Grip |
| Chris Ritter | Rigging Gaffer |
| Andrew Adams | Boom Operator |
| Ken Segal | Sound Mixer |
| Mark Larranaga | Visual Effects Supervisor |
| Sarah Sprague | Production Coordinator |
| Mia Daaja | Hairstylist |
| Peter Robb-King | Makeup Department Head |
| Justin N. Lang | Set Designer |
| Joe Schiff | ADR Editor |
| Kate Abraham | Seamstress |
| Bob Corff | Dialect Coach |
| Elizabeth Cortez | Key Hair Stylist |
| Erick Donaldson | Set Designer |
| Tommy Daguanno | Dolly Grip |
| Garrett Lowe | Scenic Artist |
| Jeffrey J. Dashnaw | Second Unit Director |
