 | Bradley Cooper als Phil Wenneck |
 | Ed Helms als Stu Price |
 | Zach Galifianakis als Alan Garner |
 | Justin Bartha als Doug Billings |
 | Ken Jeong als Mr. Chow |
 | John Goodman als Marshall |
 | Melissa McCarthy als Cassie |
 | Jeffrey Tambor als Sid Garner |
 | Heather Graham als Jade |
 | Mike Epps als Black Doug |
 | Sasha Barrese als Tracy Garner |
 | Jamie Chung als Lauren |
 | Sondra Currie als Linda |
 | Gillian Vigman als Stephanie |
 | Oliver Cooper als Pharmacy Assistant |
 | Mike Vallely als Nico |
 | Grant Holmquist als Tyler |
 | Oscar Torre als Officer Vasquez |
 | Jonny Coyne als Hector |
 | Silvia Curiel als House Keeper |
 | Betty Murphy als Cassie's Mom |
 | Jim Lau als Chief Prison Guard |
 | Lela Loren als Female Officer |
 | Harrison Forsyth als Timothy |
 | Scott Anthony Leet als Henchman #1 |
 | Tim Sitarz als Henchman #2 |
| Roger Schueller als Priest at Funeral |
| Jenny Ladner als Party Girl |
| Max Aronoff-Sher als Freeway Boy |
 | Emma Wetzel als Freeway Girl |
 | Todd Phillips als Mr. Creepy (uncredited) |
 | Danny Le Boyer als Henchman #5 (uncredited) |
| Damion Poitier als Henchman #6 (uncredited) |
 | Lewis Tan als Prison Guard (uncredited) |
 | Tiffany Tynes als Casino Hottie (uncredited) |
| Sasha milan |
| Jon Lucas | Characters |
| Keith Sayer | Makeup Department Head |
| Todd Phillips | Producer |
| Angel Radefeld | Makeup Artist |
| Austin Gorg | Art Direction |
| Gene Serdena | Set Decoration |
| Rebecca DeHerrera | Makeup Artist |
| Scott Moore | Characters |
| Todd Phillips | Director |
| Lawrence Sher | Director of Photography |
| J.C. Spink | Executive Producer |
| Koji Ohmura | Makeup Effects |
| Janeen Schreyer | Makeup Artist |
| Christophe Beck | Original Music Composer |
| Scott Budnick | Executive Producer |
| Thomas Tull | Executive Producer |
| Mindy Marin | Casting |
| Mark Garbarino | Makeup Artist |
| Craig Mazin | Writer |
| Daniel Goldberg | Producer |
| Jeff Groth | Editor |
| Debra Neil-Fisher | Editor |
| Todd Phillips | Writer |
| David Siegel | Production Manager |
| Louise Mingenbach | Costume Design |
| Maher Ahmad | Production Design |
| Luke Kalteux | Lighting Technician |
| Mark Edward Wright | Visual Effects Editor |
| Joseph Garner | Associate Producer |
| Chris Lowenstein | Line Producer |
| Jeffrey Wetzel | Co-Producer |
| Sasha Paracels | Associate Producer |
| Michael Mikita Jr. | Painter |
| Thomas T. Taylor | Set Designer |
| Bruce Tanis | Sound Effects Editor |
| Jody Rogers | Visual Effects Editor |
| Russell Farmarco | Dialogue Editor |
| Daniela Kurrie | Tailor |
| Scott R. Fisher | Special Effects Coordinator |
| Roopesh Gujar | Visual Effects Producer |
| Alan Caudillo | Camera Operator |
| Fernand Bos | Music Editor |
| David V. Butler | Supervising Dialogue Editor |
| Lee Gilmore | Sound Effects Editor |
| Robert Stadd | Visual Effects Supervisor |
| Richie Moore | Camera Operator |
| Raj Uppal | Production Design |
| C. Douglas Cameron | Boom Operator |
| Kelly Rae Kenan Green | Visual Effects Coordinator |
| Corey Bronson | Set Costumer |
| Tiffany Busche | Key Costumer |
| Jordan Corngold | Music Editor |
| Jason W. Jennings | Sound Designer |
| Katrissa 'Kat' Peterson | Visual Effects Coordinator |
| Gregory Alpert | Location Manager |
| George Drakoulias | Music Supervisor |
| Frédéric North | Aerial Coordinator |
| Chad Simpson | Painter |
| Kevin Kliesch | Orchestrator |
| Patricia Androff | Key Makeup Artist |
| Dale Snyder | Propmaker |
| Thomas Whiting | Supervising ADR Editor |
| Melinda Sue Gordon | Still Photographer |
| John M. 'Jack' Wright | Key Costumer |
| Jason Ruder | Supervising Music Editor |
| Steve Borgese | Greensman |
| Trish Gallaher Glenn | Property Master |
| Chad Eshbaugh | Techno Crane Operator |
| Peggy Pere | Aerial Coordinator |
| Cameron Frankley | Sound Designer |
| Carla Farmer | Hairstylist |
| Viola Rock | Makeup Artist |
| Sean Patrick Crowell | Key Grip |
| Daniel C. Gold | Camera Operator |
| Geoffrey Haley | Steadicam Operator |
| Steve Woroniecki | Location Manager |
| Bryan Belair | Construction Coordinator |
| Andrea Carter | Art Department Coordinator |
| Laurel Frushour | Set Costumer |
| Mitchell Ray Kenney | Costume Supervisor |
| Jules Carideo | Production Coordinator |
| Luis Galdames | Sound Effects Editor |
| Frédéric North | Pilot |
| Anna Rane | Script Supervisor |
| Allen Coulter | Set Designer |
| Jack Gill | Stunt Coordinator |
| Hans Bjerno | Aerial Director of Photography |
| Randall Poster | Music Supervisor |
| Yeşim "Shimmy" Osman | Hairstylist |
| Michelle Millay | Sculptor |
| Ray Maxwell | Propmaker |
| Christopher Allen Nelson | Special Effects Makeup Artist |
| Eddie Braun | Stunts |
| Richard Anderson | Grip |
| Weston Middleton | Production Assistant |
| Jack Gill | Second Unit Director |
| Danielle Burgio | Stunts |
| Todd Harris | Storyboard Artist |
