 | Humphrey Bogart als Samuel Spade |
 | Mary Astor als Brigid O'Shaughnessy |
 | Gladys George als Iva Archer |
 | Peter Lorre als Joel Cairo |
 | Barton MacLane als Lt. of Detectives Dundy |
 | Lee Patrick als Effie Perine |
 | Sydney Greenstreet als Kasper Gutman |
 | Ward Bond als Det. Tom Polhaus |
 | Jerome Cowan als Miles Archer |
 | Elisha Cook Jr. als Wilmer Cook |
 | James Burke als Luke |
 | Murray Alper als Frank Richman |
 | John Hamilton als District Attorney Bryan |
 | Charles Drake als Reporter (uncredited) |
 | Chester Gan als Bit Part (uncredited) |
 | Creighton Hale als Stenographer (uncredited) |
 | Robert Homans als Policeman (uncredited) |
 | William Hopper als Reporter (uncredited) |
 | Walter Huston als Captain Jacoby (uncredited) |
 | Hank Mann als Reporter (uncredited) |
 | Jack Mower als Announcer (uncredited) |
 | Emory Parnell als Ship's Mate (uncredited) |
| Adolph Deutsch | Original Music Composer |
| Orry-Kelly | Costume Design |
| Hal B. Wallis | Executive Producer |
| John Huston | Director |
| Arthur Edeson | Director of Photography |
| Robert M. Haas | Art Direction |
| Thomas Richards | Editor |
| John Huston | Screenplay |
| Perc Westmore | Makeup Artist |
| Leo F. Forbstein | Music Director |
| Frank McCoy | Makeup Artist |
| Mike Joyce | Camera Operator |
| Jean Udko | Hairstylist |
| Jack Sullivan | Assistant Director |
| Arthur Lange | Orchestrator |
| Dashiell Hammett | Novel |
| Henry Blanke | Associate Producer |
| Al Alleborn | Unit Manager |
| Claude Archer | Assistant Director |
| John Prettyman | Second Assistant Director |
| John Gilbert Kissel | Props |
| Keefe Maley | Assistant Property Master |
| William McConnell | Scenic Artist |
| Oliver S. Garretson | Sound |
| William Conger | Gaffer |
| E.F. Dexter | Grip |
| Mack Elliott | Still Photographer |
| Wally Meinardus | Assistant Camera |
| William Steudeman | Best Boy Grip |
| Burrell Kring | Wardrobe Master |
| Cora Lobb | Wardrobe Master |
| Louis Kaufman | Musician |
| Meta Carpenter | Script Supervisor |
| Robert Foulk | Dialogue Coach |
