 | David Bowie als Thomas Jerome Newton |
 | Rip Torn als Nathan Bryce |
 | Candy Clark als Mary-Lou |
 | Tony Mascia als Arthur |
 | Buck Henry als Oliver Farnsworth |
 | Bernie Casey als Peters |
 | Adrienne La Russa als Helen |
 | Claudia Jennings als Peters' Wife |
 | Rick Riccardo als Trevor |
 | Jim Lovell als James Lovell |
 | Hilary Holland als Jill |
| Linda Hutton als Elaine |
| Jackson D. Kane als Professor Canutti |
| Lilybelle Crawford als Jewelery Store Owner |
| Richard Breeding als Receptionist |
| Albert Nelson als Waiter |
| Peter Prouse als Peters' Associate |
| John Phillips | Original Music Composer |
| Graeme Clifford | Editor |
| Si Litvinoff | Executive Producer |
| Michael Deeley | Producer |
| Brian Eatwell | Production Design |
| Nicolas Roeg | Director |
| Anthony B. Richmond | Director of Photography |
| May Routh | Costume Design |
| Barry Spikings | Producer |
| Paul Mayersberg | Screenplay |
| Walter Tevis | Novel |
| Stomu Yamashta | Original Music Composer |
| Robin Gregory | Sound Recordist |
| Marilyn Clarke | Production Coordinator |
| Ronald Cook | Production Accountant |
| John Peverall | Associate Producer |
| Simon Wakefield | Set Decoration |
| Tom Raeburn | Property Master |
| Gordon Hayman | Camera Operator |
| Chuck White | Still Photographer |
| Kip Gowans | Assistant Director |
| Martin Samuel | Hairstylist |
| Terry Sharratt | Boom Operator |
| Richard Graydon | Stunt Coordinator |
| Martin Evans | Gaffer |
| Linda DeVetta | Makeup Artist |
| Ellis Burman Jr. | Makeup Effects |
| Roy Stevens | Production Manager |
| Susanna Merry | Continuity |
| Michael Ellis | Sound Editor |
| Matthew Norris | Stunt Double |
