 | Charlton Heston als Robert Neville |
 | Anthony Zerbe als Matthias |
 | Rosalind Cash als Lisa |
 | Paul Koslo als Dutch |
 | Eric Laneuville als Richie |
 | Lincoln Kilpatrick als Zachary |
 | Anna Aries als Woman in Cemetery Crypt |
 | Brian Tochi als Tommy |
 | DeVeren Bookwalter als Family Member |
 | John Dierkes als Family Member |
 | Jill Giraldi als Little Girl |
| Monika Henreid als Family Member |
| Linda Redfearn als Family Member |
| Forrest Wood als Family Member |
| Steve Goldstein als Last Boy |
| Richard Matheson | Novel |
| John William Corrington | Screenplay |
| Walter Seltzer | Producer |
| William H. Ziegler | Editor |
| Russell Metty | Director of Photography |
| Joyce Hooper Corrington | Screenplay |
| Boris Sagal | Director |
| Ron Grainer | Original Music Composer |
| Art Loel | Art Direction |
| Walter M. Simonds | Art Direction |
| William L. Kuehl | Set Decoration |
| Robert Martin | Sound |
| Jack Roberts | Casting |
| Frank L. Brown | Set Dresser |
| A. Paul Pollard | Special Effects |
| Shirley Cohen | Production Assistant |
| Michael Hancock | Makeup Artist |
| Jean Burt Reilly | Hair Supervisor |
| Frank Baur | Unit Production Manager |
| Gordon Bau | Makeup Supervisor |
| Sherry Wilson | Hairdresser |
| Whitey Hughes | Stunts |
| Buddy Joe Hooker | Stunts |
