 | Bryan Cranston als Mack |
 | Sam Rockwell als Ivan (voice) |
 | Brooklynn Prince als Ruby (voice) |
 | Angelina Jolie als Stella (voice) |
 | Danny DeVito als Bob (voice) |
 | Ariana Greenblatt als Julia |
 | Helen Mirren als Snickers (voice) |
 | Phillipa Soo als Thelma (voice) |
 | Mike White als Frankie (voice) / Passing Driver |
 | Ron Funches als Murphy (voice) |
 | Chaka Khan als Henrietta (voice) |
 | Ramón Rodríguez als George |
 | Owain Arthur als Castello |
 | Kevin Mathurin als Mike |
 | Hannah Bourne als Helen |
 | Betsy Graver als Mother In Park |
| Beckett Handley als Boy In Photo |
| Larry Ridley als News Reporter |
 | Eleanor Matsuura als Candace Taylor |
 | Kriss Dillon als Animal Inspector #1 |
 | Max Dowler als Animal Inspector #2 |
 | Indira Varma als Dr. Maya Wilson |
| Gary Greenham als Cage Guy |
 | Davina Sitaram als Passerby |
| Filiz Fairweather als Mother With Stroller |
 | Jacqueline Ramnarine als Woman Watching The Show |
| Ireland Frost als Mall Protester |
| Dean Phillippi Sr. als RV Camper Driver |
| Jude Allenby-dos Santos als Kev (Boy In Mall) |
| Jeffrey Crisp als Man Driving Car |
 | Tyrone Love als Mall Cop |
| Sean Casey als Driver |
| Danny La Placa als Neighbor |
| Roberto Vivancos als Richard Moore |
| Richard J. Valentine als Mall Protester |
 | Jeremy Oliver als Circus Visitor |
| Jessica Hyde als Mall Patron (voice) |
| Thea Sharrock | Director |
| Katherine Applegate | Book |
| Ronan Binding | Animation |
| Ben Meechan | Sound Effects Editor |
| Sue Baden-Powell | Executive Producer |
| Angelina Jolie | Producer |
| Thea Sharrock | Executive Producer |
| Allison Shearmur | Producer |
| Mike White | Screenplay |
| Brigham Taylor | Producer |
| Craig Armstrong | Original Music Composer |
| Molly Hughes | Production Design |
| Randi Hiller | Casting Director |
| Barney Pilling | Editor |
| Florian Ballhaus | Director of Photography |
| Jill Taylor | Costume Design |
| Alex Baily | Art Direction |
| Hattie Storey | Assistant Art Director |
| Louise Cassettari | Costume Supervisor |
| James Mather | Supervising Sound Editor |
| Indica Watson | Thanks |
| Ben Aghdami | Visual Effects Producer |
| Jim Sparrow | Creature Design |
| Tom Browne | Second Assistant Director |
| Rosie Goodwin | Set Decoration |
| Derek Burgess | VFX Editor |
| Phil Booth | First Assistant Director |
| Martin Foley | Supervising Art Director |
| Nick Davis | Visual Effects Supervisor |
| Caimin Bourne | Special Effects Supervisor |
| Oliver Goodier | Art Direction |
| James M. Spencer | Assistant Art Director |
| Sue Baden-Powell | Unit Production Manager |
| Rebecca Adams | Post Production Supervisor |
| Joe Hopker | Makeup & Hair |
| Garth Gutteridge | Special Effects Technician |
| Oliver Cockerham | Production Coordinator |
| Hayley Carmichael | Thanks |
| Jules Baker-Smith | Associate Producer |
| Emma Mallett | Unit Production Manager |
| Katren Wood | Assistant Set Decoration |
| Gabor Kerekes | Key Makeup Artist |
| Santiago Colomo | Animation Supervisor |
| Greg Fisher | Animation Director |
| Victor Rivas Alvarez | Digital Compositor |
| Suzy Strawn Scott | Studio Teacher |
