 | Robin Wright als Pippa Lee |
 | Alan Arkin als Herb Lee |
 | Keanu Reeves als Chris Nadeau |
 | Julianne Moore als Kat |
 | Winona Ryder als Sandra Dulles |
 | Mike Binder als Sam Shapiro |
 | Cornel West als Don Sexton |
 | Zoe Kazan als Grace Lee |
 | Maria Bello als Suky Sarkissian |
 | Shirley Knight als Dot Nadeau |
 | Blake Lively als Young Pippa Lee |
 | Monica Bellucci als Gigi Lee |
 | Adam Shonkwiler als Chester Sarkissian - Age 22 |
 | Myra Lucretia Taylor als Night Nurse |
 | Robin Weigert als Aunt Trish |
 | Ryan McDonald als Ben Lee |
 | Tim Guinee als Des Sarkissian |
 | Christin Sawyer Davis als Shelly |
 | Joan Copeland als Piano Player |
| Rebecca Miller | Director |
| Rebecca Miller | Screenplay |
| Michael Rohatyn | Original Music Composer |
| Dede Gardner | Producer |
| Michael Shaw | Production Design |
| Lemore Syvan | Producer |
| Declan Quinn | Director of Photography |
| Sabine Hoffman | Editor |
| Cindy Tolan | Casting |
| Jennifer von Mayrhauser | Costume Design |
| Cherish M. Hale | Set Decoration |
| Tom Johnson | Sound Re-Recording Mixer |
| Linda Cohen | Music Supervisor |
| Douglas Crosby | Stunt Coordinator |
| Connie Brink | Special Effects Coordinator |
| LuAnn Claps | Makeup Department Head |
| Lola Belsito | Production Supervisor |
| Michael W. Brennan | Rigging Gaffer |
| Russ Senzatimore | First Assistant Editor |
| Rebecca Miller | Novel |
| Sarah Gaines | Supervising Sound Editor |
| Brant S. Fagan | Steadicam Operator |
| Peggy Nicholson | Hair Department Head |
| Lemore Syvan | Unit Production Manager |
| Stephanie A. Marquardt | Script Supervisor |
| John Fitzgerald | Sound Re-Recording Mixer |
| Gene Page | Still Photographer |
| Teferra McKenzie | Boom Operator |
| Tom Johnson | Sound Effects Editor |
| Robert Sciretta | Gaffer |
| Parris Mayhew | Steadicam Operator |
| Jeff Pullman | Sound Mixer |
| Brad Pitt | Executive Producer |
| Jeff Sagansky | Executive Producer |
| Warren T. Goz | Executive Producer |
| Stewart McMichael | Executive Producer |
| Jill Footlick | Executive Producer |
| Jean-Luc De Fanti | Executive Producer |
| Jeremy Kleiner | Executive Producer |
| Tom O'Connor | Driver |
