 | Gary Oldman als George Smiley |
 | Colin Firth als Bill Haydon |
 | Tom Hardy als Ricki Tarr |
 | John Hurt als Control |
 | Toby Jones als Percy Alleline |
 | Mark Strong als Jim Prideaux |
 | Benedict Cumberbatch als Peter Guillam |
 | Ciarán Hinds als Roy Bland |
 | David Dencik als Toby Esterhase |
 | Kathy Burke als Connie Sachs |
 | Stephen Graham als Jerry Westerby |
 | Simon McBurney als Oliver Lacon |
 | Svetlana Khodchenkova als Irina |
 | Roger Lloyd Pack als Mendel |
 | Konstantin Khabenskiy als Polyakov |
 | Christian McKay als Mackelvore |
 | Zoltán Mucsi als Magyar |
 | Péter Kálloy Molnár als Hungarian Waiter |
 | Ilona Kassai als Woman in Window |
 | Imre Csuja als KGB Agent |
 | Arthur Nightingale als Bryant |
 | Amanda Fairbank-Hynes als Belinda |
| Peter McNeil O'Connor als Fawn |
 | Matyelok Gibbs als Mrs Pope-Graham |
 | Philip Hill-Pearson als Norman |
 | Jamie Thomas King als Kaspart |
 | Stuart Graham als Minister |
| Sarah-Jane Robinson als Mary Alleline |
 | Katrina Vasilieva als Ann Smiley |
 | Linda Marlowe als Mrs McCraig |
| William Haddock als Bill Roach |
| Erskine Wylie als Spikeley |
 | Philip Martin Brown als Tufty Thesinger |
| Tomasz Kowalski als Boris |
| Alexandra Salafranca als Turkish Mistress |
 | Denis Khoroshko als Ivan |
| Oleg Dzhabrailov als Sergei |
| Gillian Stevenson als Listening Woman |
| Nick Hopper als Janitor Alwyn |
 | Laura Carmichael als Sal |
 | Rupert Procter als Guillam's Boyfriend |
 | John le Carré als Christmas Party Guest |
 | Michael Sarne als Karla (Voice) |
 | Jean-Claude Jay als French Man at Residency |
| Tom Stuart als Ben |
| Harvey Walsh als Schoolboy (uncredited) |
| Tomas Alfredson | Director |
| John le Carré | Novel |
| Peter Straughan | Screenplay |
| Bridget O'Connor | Screenplay |
| Tim Bevan | Producer |
| Eric Fellner | Producer |
| Robyn Slovo | Producer |
| Hoyte van Hoytema | Director of Photography |
| Jacqueline Durran | Costume Design |
| Jina Jay | Casting |
| Dino Jonsäter | Editor |
| Maria Djurkovic | Production Design |
| Pilar Foy | Art Direction |
| Tatiana Macdonald | Set Decoration |
| Dan Grace | Costume Supervisor |
| Mark Raggett | Supervising Art Director |
| Tom Brown | Supervising Art Director |
| Libbie Barr | Script Supervisor |
| Nick Angel | Music Supervisor |
| Alberto Iglesias | Original Music Composer |
| Felicity Bowring | Hair Designer |
| Donald McInnes | Key Hair Stylist |
| Klári Szinek | Key Hair Stylist |
| Hildegard Haide | Key Makeup Artist |
| Lizzie Lawson | Key Makeup Artist |
| Ebru Kiziltan | Key Makeup Artist |
| Felicity Bowring | Makeup Designer |
| Ayberk Dorukhan Erdogdu | Art Department Coordinator |
| Chris Cull | Property Master |
| Tunc Erguden | Property Master |
| Ruslan Ogorodnik | 3D Artist |
| Aron Hjartarson | CG Supervisor |
| Aimee Dadswell | Visual Effects Producer |
| Nick King | Visual Effects Producer |
| Sara Trezzi | Visual Effects Producer |
| Fredrik Nord | Visual Effects Supervisor |
| Sirio Quintavalle | Visual Effects Supervisor |
| Peter Taylor | Camera Operator |
| Jallo Faber | Second Unit Director of Photography |
| Alan Martin | Gaffer |
| Gábor Hevesi | Gaffer |
| Larry S. Prinz | Gaffer |
| János Kiss | Key Grip |
| Hasan Ormanlar | Key Grip |
| Jack English | Still Photographer |
| István Török | Dolly Grip |
| Abigail Barbier | ADR Voice Casting |
| Louis Elman | ADR Voice Casting |
| Nick Foley | ADR Voice Casting |
| Andrea Cripps | Assistant Costume Designer |
| Hilal Sezer | Assistant Costume Designer |
| Gábor Homonnay | Costume Supervisor |
| Nicholas Roche-Gordon | Key Set Costumer |
| Klári Riesz | Key Set Costumer |
| Katalin Ujvari | Key Set Costumer |
| Rosaria Coppola | Seamstress |
| Mária Raffai | Seamstress |
| James Bellamy | Music Editor |
| Gail Behrmann | Researcher |
| Christophe Maratier | Armorer |
| Béla Gajdos | Armorer |
| Mark Trend | First Assistant Editor |
| Mark Holt | Special Effects Supervisor |
| Gyula Krasnyánszky | Pyrotechnic Supervisor |
| Chris Murphy | Boom Operator |
| György Rajna | Boom Operator |
| Orin Beaton | Boom Operator |
| Márton Kristóf | Cableman |
| Barnaby Smyth | Foley |
| Howard Bargroff | Sound Re-Recording Mixer |
| Doug Cooper | Sound Re-Recording Mixer |
| Stephen Griffiths | Supervising Sound Editor |
| Andy Shelley | Supervising Sound Editor |
| Ildikó Aradi | Hairstylist |
| Kirsten Lane | Music Consultant |
| Dixie Chassay | Casting Associate |
| Zsuzsa Mihalek | Set Decoration |
| Nellie Burroughes | Stunt Double |
