 | Charlie Adler als Buster Bunny / Usher (voice) |
 | Tress MacNeille als Babs Bunny / Big Boo / Babs' Mother / Emily Duff / Roseanne Barr / Barbara Walters / Arsenio Hall / Additional Voices (voice) |
 | Joe Alaskey als Plucky Duck / Tupelo Toad / Johnny Carson / Ed McMahon / Elmer Fudd / Additional Voices (voice) |
 | Don Messick als Hamton J. Pig / Radio Announcer (voice) |
 | Jonathan Winters als Wade Pig / Superman (voice) |
 | Edie McClurg als Winnie Pig (voice) |
 | Frank Welker als Uncle Stinky Pig / Byron Basset / Furrball / Little Beeper / Gogo Dodo / Vinnie / Mac Duff / Additional Voices (voice) |
 | Cree Summer als Elmyra Duff / Mary Melody / Oprah Winfrey (voice) |
 | Sorrell Booke als Big Daddy Boo (voice) |
 | Rob Paulsen als Fowlmouth / Johnny Pew / Banjo the Woodpile Possum / Mr. Hitcher / Manager / Additional Voices (voice) |
 | Maurice LaMarche als Dizzy Devil / David Letterman / Horatio / Theatre Voice (voice) |
 | Gail Matthius als Shirley the Loon / Sissy Boo (voice) |
 | Kath Soucie als Fifi La Fume / Little Boo / Little Sneezer / Bimbette Skunk (voice) (as Kath Souci) |
 | Candi Milo als Sweetie Pie (voice) |
 | Paul Julian als Road Runner (archive sound) (uncredited) |
| Bruce Broughton | Music |
| Steven Spielberg | Executive Producer |
| Tom Ruegger | Writer |
| Jean MacCurdy | Production Manager |
| Sherri Stoner | Writer |
| Tom Ruegger | Producer |
| Sherri Stoner | Associate Producer |
| Paul Dini | Writer |
| Frank Marshall | Production Supervisor |
| Kathleen Kennedy | Production Supervisor |
| Nicholas Hollander | Writer |
| Lisa Leonardi-Knight | Color Designer |
| Yoshitake Iwakami | Animation |
| Ken Boyer | Director |
| Alfred Gimeno | Director |
| Rich Arons | Director |
| Kent Butterworth | Director |
| Byron Vaughns | Director |
| Art Leonardi | Director |
| Barry Caldwell | Director |
| Yoshihiro Kasahara | Editor |
| Jean MacCurdy | Executive In Charge Of Production |
| Bruce Broughton | Music Supervisor |
| Steven Bramson | Music |
| Don Davis | Music |
| Richard Stone | Music |
| Stephen James Taylor | Music |
| Mark Watters | Music |
| Albert Lloyd Olson | Music |
| Andrea Romano | Casting |
| Rich Arons | Storyboard Artist |
| Ken Boyer | Storyboard Artist |
| Yi-Chih Chen | Storyboard Artist |
| Jill Colbert | Storyboard Artist |
| Humberto De La Fuente | Storyboard Artist |
| Daniel De La Vega | Storyboard Artist |
| Alberto De Mello | Storyboard Artist |
| Flamarion Ferreira | Storyboard Artist |
| Ian Findley | Storyboard Artist |
| Paul Fisher | Storyboard Artist |
| Eddie Fitzgerald | Storyboard Artist |
| Jim Fletcher | Storyboard Artist |
| Alfred Gimeno | Storyboard Artist |
| Warren Greenwood | Storyboard Artist |
| Dan Haskett | Storyboard Artist |
| Tenny Henson | Storyboard Artist |
| Garrett Ho | Storyboard Artist |
| Enrique May | Storyboard Artist |
| Douglas McCarthy | Storyboard Artist |
| Chris Reccardi | Storyboard Artist |
| Lenord Robinson | Storyboard Artist |
| Byron Vaughns | Storyboard Artist |
| Joe Gall | Supervising Film Editor |
| Kazuhide Tomonaga | Animation Director |
| Toshihiko Masuda | Animation Director |
| Kenji Hachizaki | Animation Director |
| Hiroyuki Aoyama | Animation Director |
| Shuichi Hirata | Art Direction |
| Tom Ruegger | Lyricist |
| Wayne Kaatz | Lyricist |
| Paul Dini | Lyricist |
| Sherri Stoner | Lyricist |
| Hiroshi Aoyama | Other |
