 | Shia LaBeouf als Sam Witwicky |
 | Megan Fox als Mikaela Banes |
 | Josh Duhamel als Major Lennox |
 | Tyrese Gibson als USAF Chief Master Sergeant Epps |
 | John Turturro als Seymour Simmons |
 | Ramón Rodríguez als Leo Spitz |
 | Kevin Dunn als Ron Witwicky |
 | Julie White als Judy Witwicky |
 | Isabel Lucas als Alice |
 | John Benjamin Hickey als Galloway |
 | Matthew Marsden als Special Air Service Forces |
 | Andrew Howard als Special Air Service Forces |
 | Michael Papajohn als Cal |
 | Glenn Morshower als General Morshower |
 | John Eric Bentley als Aide |
 | Erin Naas als Arcee Rider |
 | Spencer Garrett als Air Force Chief of Staff |
 | Rainn Wilson als Professor Colan |
 | Katie Lowes als April the Resident Assistant |
 | Jonathon Trent als Fassbinder |
 | Walker Howard als Sharsky |
 | America Olivo als Frisbee Girl |
 | Aaron Hill als Frat Guy |
 | Jareb Dauplaise als Frat Guy |
 | John Sanderford als Pundit |
 | Christopher Curry als Pundit |
 | Cas Anvar als Egyptian Interpol Officer #1 |
 | Michael Benyaer als Egyptian Interpol Officer #2 |
 | Deep Roy als Egyptian Guard |
 | Ruben Martinez als Bedouin with Donkey |
| Ralph Meyering Jr. als NORAD General |
 | Aaron Norvell als Air Force Military Police |
 | Eric Pierpoint als NSA Officer |
 | Annie Korzen als Simmons Mom |
 | Sean T. Krishnan als Yakov |
 | David Bowe als Smithsonian Guard |
 | Kamal Jones als Smithsonian Guard |
 | Aaron Lustig als Reporter |
 | Jim Holmes als Reporter |
| Kristen Welker als Reporter |
 | Cornell Womack als FBI Director |
| David Luengas als Ticket Agent |
 | Derek Alvarado als Joint Ops Staff |
 | Alex Fernandez als Joint Ops Staff |
 | Casey Nelson als Joint Ops Staff |
| Jason Roehm als Joint Ops Staff |
 | John Nielsen als USS Roosevelt Captain |
 | Rick Cramer als Diego Garcia Soldier |
 | Arnold Chun als Diego Garcia Soldier |
| Marvin Jordan als Diego Garcia Soldier |
 | Marc Evan Jackson als Commander, US Central Command |
 | Josh Kelly als Strike Force Team |
| Jayson Floyd als Strike Force Team |
 | Geoff Reeves als Strike Force Team |
| Aaron Garrido als Strike Force Team |
 | Joel Lambert als Strike Force Team |
| David Paul Olsen als Strike Force Team |
 | Brian Shehan als Strike Force Team |
 | Peter Cullen als Optimus Prime (voice) |
 | Mark Ryan als Jetfire (voice) |
 | Reno Wilson als Mudflap (voice) |
 | Jess Harnell als Ironhide (voice) |
 | Robert Foxworth als Ratchet (voice) |
 | André Sogliuzzo als Sideswipe (voice) |
 | Grey DeLisle als Arcee (voice) |
 | Hugo Weaving als Megatron (voice) |
 | Tony Todd als The Fallen (voice) |
 | Charlie Adler als Starscream (voice) |
 | Frank Welker als Soundwave / Devastator / Reedman / Grindor (voice) |
 | Tom Kenny als Wheelie / Skids (voice) |
| Calvin Wimmer als Wheelbot (voice) |
 | John Di Crosta als Doctor (voice) |
 | Michael York als Prime #1 (voice) |
 | Kevin Michael Richardson als Prime #2 / Skipjack / Rampage (voice) |
 | Robin Atkin Downes als Prime #3 (voice) |
| Jenn An als Astronomy Student (uncredited) |
 | Alexandra Begg als College Student (uncredited) |
 | Caitlin Dulany als CNN Reporter (uncredited) |
 | Andrew Hwang als Mandarin Blogger (uncredited) |
 | Matt Iseman als C-17 Pilot (uncredited) |
 | Shayna Ryan als French Cafe Patron (uncredited) |
 | Karina Michel als Reporter (uncredited) |
| Lorenzo di Bonaventura | Producer |
| Steven Spielberg | Executive Producer |
| Michael Bay | Director |
| Don Murphy | Producer |
| Ian Bryce | Producer |
| Tom DeSanto | Producer |
| Travis Tohill | Animation |
| Denise Chamian | Casting |
| Jennifer Williams | Set Decoration |
| Edouard F. Henriques | Makeup Department Head |
| Deborah Lynn Scott | Costume Design |
| Nigel Phelps | Production Design |
| Lisa Lovaas | Costume Supervisor |
| Ben Seresin | Director of Photography |
| Jon Billington | Supervising Art Director |
| Michael Bay | Executive Producer |
| Erik Baker | Animation |
| Hugo Dominguez | Digital Effects Supervisor |
| Emilio Ghorayeb | Animation |
| Mike Marcuzzi | Digital Effects Supervisor |
| Brian Avery | Stunts |
| Greg P. Russell | Sound Re-Recording Mixer |
| Robert Zuckerman | Still Photographer |
| Jacques Jouffret | Camera Operator |
| Steve Jablonsky | Original Music Composer |
| Greg ten Bosch | Sound Effects Editor |
| Ethan van der Ryn | Supervising Sound Editor |
| P.K. Hooker | Sound Effects Editor |
| Roger Barton | Editor |
| Ramiro Belgardt | Music Editor |
| Paul Rubell | Editor |
| Alex Gibson | Music Editor |
| Gary Summers | Sound Re-Recording Mixer |
| Warren Hendriks | Sound Effects Editor |
| Erik Aadahl | Supervising Sound Editor |
| Joel Negron | Editor |
| Karen Golden | Script Supervisor |
| Jacques Jouffret | Steadicam Operator |
| Yolanda Toussieng | Hair Department Head |
| Tom Muldoon | Editor |
| Theresa Greene | Art Department Coordinator |
| John Marquis | Sound Effects Editor |
| Geoffrey Patterson | Sound Mixer |
| K.C. Hodenfield | Associate Producer |
| Matthew Cohan | Associate Producer |
| Brian Goldner | Executive Producer |
| Mark Vahradian | Executive Producer |
| Allegra Clegg | Co-Producer |
| Kenny Bates | Co-Producer |
| Kevin Kaska | Orchestrator |
| Khristian Lupo | Stunts |
| Ulrika Akander | Dialogue Editor |
| Wayne Lemmer | Dialogue Editor |
| Roberto Orci | Writer |
| Alex Kurtzman | Writer |
| Ehren Kruger | Writer |
| Frank Torres | Stunts |
| Steve Kelso | Stunt Driver |
| Marc Scizak | Stunt Double |
| Tarah Paige | Stunt Double |
| Sierra Fisk | Stunts |
| Jen Weissenberg | Stunts |
| John Branagan | Stunt Driver |
| Hans Zimmer | Thanks |
| Brieann Rich | Stunt Driver |
| Melissa Hartman | Stunts |
| Jimmy N. Roberts | Stunt Driver |
| Stella Angelova | Stunt Double |
| Nicholas Rich | Stunt Driver |
| Randy Peters | Stunt Driver |
| Daniel Arrias | Stunt Double |
| Shelly Ward | Stunts |
| Lin Oeding | Stunt Driver |
| Stacey Carino | Stunt Double |
| Peter Bucossi | Stunt Driver |
| Jaroslav Peterka | Stunt Driver |
| Jindřich Klaus | Stunt Driver |
| Tom Harper | Stunt Driver |
| Lauren Cashatt | Stunts |
| Brock Little | Stunts |
| Mike Majesky | Stunt Driver |
| Jessie Graff | Stunt Double |
| Paul Bucossi | Stunt Driver |
| Lauren Mary Kim | Stunts |
| Richard Epper | Stunts |
| Hubie Kerns Jr. | Stunt Driver |
| Donna Evans | Stunts |
| Stephen W. Schriver | Stunt Double |
| Laurence Todd Rosenthal | Stunt Double |
| Alicia Vela-Bailey | Stunts |
| Joey Freitas | Stunt Driver |
| Jeff Lew | Animation |
| Robert Stoneman | First Assistant Camera |
| Allegra Clegg | Unit Production Manager |
| K.C. Hodenfield | First Assistant Director |
| Bruce Moriarty | First Assistant Director |
| Chris Castaldi | Second Assistant Director |
| Hope Garrison | Second Assistant Director |
| Michelle McGonagle | Associate Producer |
| Scott Benza | Animation Supervisor |
| Wayne Billheimer | Visual Effects Producer |
| Kenny Bates | Stunt Coordinator |
| Julian Ashby | Art Direction |
| Sean Haworth | Art Direction |
| Naaman Marshall | Art Direction |
| Ben Procter | Art Direction |
| Page Buckner | Assistant Art Director |
| Martha Johnston | Assistant Art Director |
| Robert W. Joseph | Assistant Art Director |
| Philippe Carr-Forster | Camera Operator |
| Julie Pitkanen | Script Supervisor |
| Holly Davis | Assistant Costume Designer |
| Robin Beauchesne | Makeup Artist |
| Robin Beauchesne | Key Makeup Artist |
| Jennifer Bell | Hairstylist |
| Marvin Williams | Second Second Assistant Director |
| Troy Robinson | Stunt Coordinator |
| Bob Brown | Stunt Coordinator |
| Jeffrey G. Barnett | Stunts |
| Shawn Kelly | Lead Animator |
| Aja Frary | Stunts |
| Lou Pecora | Compositing Supervisor |
| George Hull | Conceptual Design |
