 | Jennifer Morrison als Amy Mayfield |
 | Matthew Davis als Travis / Trevor |
 | Hart Bochner als Professor Solomon |
 | Loretta Devine als Reese |
 | Joey Lawrence als Graham |
 | Anson Mount als Toby |
 | Jessica Cauffiel als Sandra |
 | Anthony Anderson als Stan |
 | Michael Bacall als Dirk |
 | Eva Mendes als Vanessa |
 | Marco Hofschneider als Schorm "Simon" Jabuscko |
 | Derek Aasland als P.A. Kevin |
 | Jacinda Barrett als Lisa |
| Peter Millard als Dr. Richard Fain |
| Chas Lawther als Dean Patterson |
 | Chuck Campbell als Geek in Plane |
 | Yani Gellman als Rob |
 | Jeannette Sousa als Libby |
 | Rebecca Gayheart als Brenda Bates |
| Paul Harris Boardman | Screenplay |
| Scott Derrickson | Screenplay |
| Neal H. Moritz | Producer |
| Damon Intrabartolo | Original Music Composer |
| Brian Pearson | Director of Photography |
| Amanda Goodpaster | Associate Producer |
| Michael McDonnell | Co-Producer |
| Brad Luff | Executive Producer |
| Nick Osborne | Executive Producer |
| Richard Luke Rothschild | Producer |
| Gina Matthews | Producer |
| John Ottman | Original Music Composer |
| Rob Kobrin | Editor |
| John Ottman | Editor |
| Randi Hiller | Casting |
| Mark Zuelzke | Production Design |
| Nancey Pankiw | Art Direction |
| Carol Lavoie | Set Decoration |
| Trysha Bakker | Costume Design |
| Marie-Sylvie Deveau | Costume Design |
| Karola Dirnberger | Key Hair Stylist |
| Irene Kent | Key Makeup Artist |
| Christopher J. Danton | Production Manager |
| Richard Luke Rothschild | Unit Production Manager |
| Michael Zenon | First Assistant Director |
| Patricia Joyes | Script Supervisor |
| Harry Kassardjian | Carpenter |
| Henry Ilola | Construction Coordinator |
| Hans-Heinrich Piersig | Leadman |
| Ane Christensen | Property Master |
| Chris Fix | Propmaker |
| Brian Wade | Props |
| Charles L. Dunlop | Set Designer |
| Ralph Stuart | Assistant Sound Editor |
| Colin Jones | Boom Operator |
| Rick Mitchell | Foley Editor |
| James Christopher | Sound Effects Editor |
| David E. Fluhr | Sound Re-Recording Mixer |
| Andrea Lakin | Sound Recordist |
| Richard L. Anderson | Supervising Sound Editor |
| Larz Anderson | Special Effects |
| Sarah Norton | Compositor |
| Tavia Charlton | Visual Effects Coordinator |
| Mark Savela | Visual Effects Supervisor |
| Pat Banta | Stunt Coordinator |
| Leigh Bianco | Stunts |
| Susan A. Cabral | Additional Photography |
| Roddy Kosub | Best Boy Electric |
| Tony Guerin | Camera Operator |
| Kirk Chiswell | First Assistant Camera |
| John 'Fest' Sandau | Gaffer |
| Jim Holmes | Grip |
| Robert DaPrato | Key Grip |
| Lux | Lighting Technician |
| Brad Hruboska | Steadicam Operator |
| Michael Gibson | Still Photographer |
| Courtney Gross | Casting Associate |
| Gillian Steinhardt | Assistant Costume Designer |
| Donna Butt | Set Costumer |
| Mike Milliken | Color Timer |
| Anne Richardson | Location Manager |
| Amanda Goodpaster | Music Editor |
| John Ottman | Orchestrator |
| Jeff Bell | Transportation Captain |
| Jason Leeking | Transportation Co-Captain |
| Wilfred Bell | Transportation Coordinator |
| Missy Eustermann | Post Production Accountant |
| Michael Goosen | Production Accountant |
| Kristine M. Gilbert | Production Coordinator |
| Stephanie Keating | Unit Publicist |
| Tim Singh | Second Assistant Director |
| Tyler Delben | Third Assistant Director |
| Elizabeth Kenton | ADR Editor |
| Greg Steele | ADR Mixer |
| Dan Lucas | ADR Recordist |
| Catherine Harper | Foley Artist |
| Don Givens | Foley Mixer |
| Robert Zubia | Foley Recordist |
| Mark Rice | Special Effects Assistant |
| Brad Larkin | Special Effects Technician |
| Heather Callow | Stunt Double |
| Pete Daprato | Best Boy Grip |
| Patrick King | Dolly Grip |
| Anthony Ellis | Second Assistant Camera |
| Terri Douglas | ADR Voice Casting |
| Andrea Kool | Casting Assistant |
| Helen Hand | Assistant Editor |
| Chris Lamie | Colorist |
| Jen Leonard | Assistant Location Manager |
| Carl Bainbridge | Location Production Assistant |
| Damon Intrabartolo | Conductor |
| Redd Knight | Assistant Production Coordinator |
| Richard Allen | Chief Lighting Technician |
| Chris Crowell | Digital Compositor |
| Sue Sparling | First Assistant Accountant |
| Reet Puhm | Key Scenic Artist |
| Joseph Diaz | Production Assistant |
| Vicki Dee Rock | Production Executive |
| Janet Ellis | Production Secretary |
| François Dagenais | Prosthetic Designer |
| John Ottman | Director |
| Silvio Horta | Characters |
| Alison Reid | Stunts |
| Mickey Giacomazzi | Stunts |
