 | Lupita Nyong'o als Adelaide Wilson / Red |
 | Winston Duke als Gabriel "Gabe" Wilson / Abraham |
 | Shahadi Wright Joseph als Zora Wilson / Umbrae |
 | Evan Alex als Jason Wilson / Pluto |
 | Tim Heidecker als Josh Tyler / Tex |
 | Elisabeth Moss als Kitty Tyler / Dahlia |
 | Cali Sheldon als Becca Tyler / Io |
 | Noelle Sheldon als Lindsey Tyler / Nix |
 | Yahya Abdul-Mateen II als Russell Thomas / Weyland |
 | Anna Diop als Rayne Thomas / Eartha |
 | Madison Curry als Young Adelaide Wilson / Young Red |
 | Duke Nicholson als Danny / Tony |
 | Napiera Groves als Dr. Foster / Amethyst |
 | Kara Hayward als Nancy / Syd |
 | Lon Gowan als Don / Joseph |
| Alan Frazier als Alan / Jeremiah |
 | Dustin Ybarra als Troy / Brand |
| Nathan Harrington als Glen / Jack |
 | Darrel Cherney als News Anchor (uncredited) |
| James Cobb als Don (uncredited) |
| Alessandro Garcia als EMT (uncredited) |
| David M Sandoval Jr. als Father of Family on Beach (uncredited) |
| Ashley McKoy als Teenage Adelaide Wilson / Teenage Red |
 | Jordan Peele als Dying Rabbit / Fun House Narrator (voice) |
| Jordan Peele | Director |
| Jordan Peele | Producer |
| Jason Blum | Producer |
| Sean McKittrick | Producer |
| Mike Gioulakis | Director of Photography |
| Kym Barrett | Costume Design |
| Nicholas Monsour | Editor |
| Ruth De Jong | Production Design |
| Michael Abels | Original Music Composer |
| Claudette Barius | Still Photographer |
| Jordan Peele | Writer |
| Florencia Martin | Set Decoration |
| Ian Cooper | Producer |
| Beatriz Sequeira | Executive Producer |
| Terri Taylor | Casting |
| Cara Brower | Art Direction |
| Daniel Lupi | Executive Producer |
| Chris Howland | Additional Production Sound Mixer |
| Scott Wheeler | Makeup Department Head |
| Hanny Tjan | Makeup Artist |
| Shutchai Tym Buacharern | Makeup Artist |
| Jim Hewitt | Set Designer |
| Allison Isenberg | Set Decoration Buyer |
| Ron Bartlett | Sound Re-Recording Mixer |
| Trevor Gates | Supervising Sound Editor |
| Matthew Thomas Hall | Sound Effects Editor |
| Doug Hemphill | Sound Re-Recording Mixer |
| Paul B. Knox | Sound Effects Editor |
| Lee Briggs | Visual Effects Producer |
| Grady Cofer | Visual Effects Supervisor |
| Lisa Goldberg | Visual Effects Producer |
| Mark Intravartolo | VFX Artist |
| Jeanie King | Visual Effects Producer |
| Joaquin Ludewig | VFX Artist |
| Yen Do | Set Costumer |
| Ariel Gold | Costume Supervisor |
| Jessica Posada | Set Costumer |
| Elisa Sebra | Set Costumer |
| Alice Ford | Stunts |
| John Donohue | Fight Choreographer |
| Crystal Michelle | Stunts |
| Anthony Genova | Stunts |
| Jess King | Stunts |
| Pat Millicano | Stunts |
| Skyler Millicano | Stunts |
| Matthew Miscione | Stunts |
| Rene H. Herrera | Stunts |
| James Mitchell-Clyde | Stunts |
| Nikki Stanley | Stunts |
| Jason Sweat | Stunts |
| Freddy W. Smith | Stunts |
| Keisha Tucker | Stunts |
| Trampas Thompson | Stunts |
| Mark Vanselow | Stunt Coordinator |
| Bryce Branagan | Stunts |
| Emily Brobst | Stunts |
| Janeshia Adams-Ginyard | Stunts |
| Ken Clark | Stunts |
| Dartenea Bryant | Stunt Driver |
| Guy Fernandez | Stunts |
| Michael DeCamp | Stunts |
| Joe Fidler | Stunts |
| Ram Paul Silbey | Second Assistant Director |
| Gerard DiNardi | First Assistant Director |
| Jaime Leigh McIntosh | Hair Department Head |
| Camille Friend | Hair Department Head |
| Alex Nomick | Foley Editor |
| Frances Heeber | Studio Teacher |
