 | Ben Stiller als Reuben Feffer |
 | Jennifer Aniston als Polly Prince |
 | Philip Seymour Hoffman als Sandy Lyle |
 | Debra Messing als Lisa Kramer |
 | Alec Baldwin als Stan Indursky |
 | Hank Azaria als Claude |
 | Bryan Brown als Leland Van Lew |
 | Jsu Garcia als Javier |
 | Michele Lee als Vivian Feffer |
 | Bob Dishy als Irving Feffer |
 | Missi Pyle als Roxanne |
 | Judah Friedlander als Dustin |
 | Kevin Hart als Vic |
 | Masi Oka als Wonsuk |
 | Kym Whitley als Gladys |
 | Amy Hohn als Cheryl |
 | Nathan Dean als Mitch |
 | Cheryl Hines als Catering Manager |
 | Caroline Aaron als Wedding Coordinator |
 | Christina Kirk als Party Hostess |
 | Todd Stashwick als Security Officer |
 | Robb Skyler als Basketball Player |
 | Edward Conna als Basketball Player |
 | Bruce Nozick als Executive Chef |
 | Mark Adair-Rios als Cake Decorator |
 | Michael Shamberg als Van Lew Executive |
 | Nick Jameson als Van Lew Executive |
 | Richard Willgrubs als AFLAC Executive |
| Ronald Hunter als Peanut Vendor |
| David Baron als Rabbi |
 | James DuMont als Larry |
| Nicholas Benevento als Wedding Photographer |
 | Jeff Ross als Wedding Band Leader |
 | Mitch Silpa als JC Superstar Director |
 | Robert M. Koch als Partygoer |
| Money Mark als Salsa Band Leader |
 | Theodore Shapiro als Hector |
| Claudia Tenorio Gonzales als Salsa Singer |
 | Carmit Bachar als Salsa Dancer |
| Marco De La Cruz als Salsa Dancer |
 | Alison Faulk als Salsa Dancer |
 | Tomasina Parrott als Salsa Dancer |
 | Gustavo Vargas als Salsa Dancer |
 | Allen Walls als Salsa Dancer |
| Rudy Zalez als Salsa Dancer |
| Paul Blazeak als Salsa Band |
| Richard Barron als Salsa Band |
| George Balmaseda als Salsa Band |
| Leslie Drayton als Salsa Band |
| Jose Espinosa als Salsa Band |
| Walter Miranda als Salsa Band |
| Alfredo Ortiz als Salsa Band |
| Phillip Ranelin als Salsa Band |
| Michael Wong als Salsa Band |
| Adrienne Ash als JC Superstar Singer |
 | Christine Barger als JC Superstar Singer |
| Toni Blair als JC Superstar Singer |
| Eugenia Care als JC Superstar Singer |
| Mari Endo als JC Superstar Singer |
| Mike Fujimoto als JC Superstar Singer |
| Gustavo Hernandez als JC Superstar Singer |
| Monique Jongs als JC Superstar Singer |
| Anjulie Marriott als JC Superstar Singer |
| Jeffrey Sherrard als JC Superstar Singer |
| Ryan Cross als JC Superstar Band |
| Anthony King als JC Superstar Band |
| Vernon Neilly als JC Superstar Band |
| Stuart Silverstein als JC Superstar Band |
| Theodore Shapiro | Original Music Composer |
| William Kerr | Editor |
| Nick Moore | Editor |
| Seamus McGarvey | Director of Photography |
| Kathleen Chopin | Casting |
| John Hamburg | Director |
| Anders Bard | Associate Producer |
| Danny DeVito | Producer |
| John Hamburg | Writer |
| Greg Curtis | Special Effects Coordinator |
| Jane Bartelme | Executive Producer |
| Daniel S. Levine | Executive Producer |
| Michael Shamberg | Producer |
| Stacey Sher | Producer |
| Laura Marolakos | Key Costumer |
| Michael Amorelli | Rigging Gaffer |
| Andrew Laws | Production Design |
| Martin Whist | Art Direction |
| Don Diers | Set Decoration |
| Cindy Evans | Costume Design |
| Scott Morgan | Art Department Assistant |
| Kacy Magedman | Art Department Coordinator |
| Jonas Kirk | Construction Coordinator |
| Robert W. Joseph | Leadman |
| Greg Berry | Set Designer |
| Steven Meizler | First Assistant Camera |
| George Billinger III | Steadicam Operator |
| Tracy Bennett | Still Photographer |
| Lori DeLapp | Costume Supervisor |
| Kelvin R. Trahan | Hair Department Head |
| Naomi Donne | Hairstylist |
| Trish Almeida | Key Hair Stylist |
| Ronald Hairston Jr. | Craft Service |
| Lisa Rodgers | Post Production Supervisor |
| Rick Chouinard | Transportation Captain |
| Greg Van Dyke | Transportation Co-Captain |
| Kathryn Donovan | Unit Publicist |
| Annie Welles | Script Supervisor |
| Terry Claborn | Color Timer |
| Robert Grieve | Dialogue Editor |
| Clark Campbell | First Assistant Editor |
| Paul Arnold | Electrician |
| Dayton Nietert | Gaffer |
| Karen Meisels | Casting Associate |
| Molly Allen | Location Manager |
| Charles W. Francis | Production Accountant |
| Benjamin Wienert | Boom Operator |
| Kerry P. Brown | Music Editor |
| Richard Van Dyke | Production Sound Mixer |
| Darren King | Supervising Sound Editor |
| Daniel Silverberg | First Assistant Director |
| Mary Saisselin | Set Designer |
| George Billinger III | Camera Operator |
| Mitch Dubin | Camera Operator |
| Paul Toomey | Camera Loader |
| Geoffrey Patterson | Sound Mixer |
| Todd Ellis | Property Master |
| Marc A. Hammer | Production Coordinator |
| Art Bartels | Key Grip |
| Eric Zuckerman | Casting Associate |
| James C. Taylor | Transportation Coordinator |
| Laura Steiger | Associate Editor |
| Matthew C. May | Assistant Sound Editor |
| Tanya Noel Hill | Music Editor |
| Gary Burritt | Negative Cutter |
| Randall Poster | Music Supervisor |
| Daniel M. Stillman | Unit Production Manager |
| Lisa Bloch-Tobey | Second Assistant Director |
| Alex Daniels | Stunt Coordinator |
| Mark Spath | First Assistant Camera |
| Tim Y. Wetzel | Assistant Property Master |
| Janet Sobel | Key Costumer |
| Annie Laoparadonchai | Set Costumer |
| Naomi Donne | Makeup Artist |
| Chris McMillan | Hairstylist |
| Valli O'Reilly | Makeup Artist |
| Ann Pala | Key Makeup Artist |
| Felicity Bowring | Makeup Department Head |
| JoAnn Fregalette Jansen | Choreographer |
| Steve Werblun | Storyboard Designer |
| David Raymond | Assistant Editor |
| Joel Shryack | Dialogue Editor |
| Andrew Bracken | Foley Editor |
| Joseph Schultz | Assistant Sound Editor |
| Charles Martin Inouye | Supervising Music Editor |
| Barbara Harris | ADR Voice Casting |
| Anne Fletcher | Choreographer |
| Tim Rigby | Stunts |
| Bruce Fowler | Sound Mixer |
| Amy Schmiederer | Assistant Makeup Artist |
| Yulia Gershenzon | Costumer |
| Don H. Julien | Second Second Assistant Director |
| Alex Daniels | Second Unit Director |
| David Scott | Graphic Designer |
| Miles Teves | Storyboard Artist |
| Greg Kupiec | Title Designer |
| Dylan A. Flores | ADR Mixer |
| Philip Rogers | ADR Recordist |
| Goro Koyama | Foley Artist |
| Dan Yale | Foley Supervisor |
| Jeffrey A. Humphreys | Utility Sound |
| Chris Brenczewski | Special Effects Technician |
| Michelle Rothburgh | Visual Effects Editor |
| Jennifer Brusciano | Stunt Double |
| Carolyn Sapp Daniels | Stunt Driver |
| Stanley Fernandez Jr. | Assistant Camera |
| Patrick Shelby | Best Boy Grip |
| Chuck Moya | Camera Loader |
| Jeremiah Kent | Camera Trainee |
| Jack Glenn | Dolly Grip |
| Tom Jordan | Second Assistant Camera |
| Andrew Tucker | Lead Animator |
| Joanna Brett | Wardrobe Supervisor |
| Peggy Eghbalian | Assistant Editor |
| Elizabeth Dean | Post Production Coordinator |
| Kei Rowan-Young | Assistant Location Manager |
| Rachel Swenson | Location Coordinator |
| Jim Dunbar | Music Consultant |
| Christopher A. Zwirner | Assistant Chief Lighting Technician |
| Lisa S. Beasley | Assistant Production Coordinator |
| Kelly Clear | Chief Lighting Technician |
| David S. Williams Jr. | Compositing Supervisor |
| Shaina Holmes | Digital Compositor |
| Richard Patterson | Digital Supervisor |
| Margaret Doversola | Extras Casting |
| Marybeth Martin-Eck | First Assistant Accountant |
| Cheryl Bell Hawley | Intern |
| Alexander C. Sohn | Payroll Accountant |
| Trent Broin | Production Assistant |
| Jenny Fumarolo | Production Secretary |
| Abbie Ludwig | Second Assistant Accountant |
| Danielle Burgio | Stunts |
| Janie Liszewski | Stunts |
| Samantha Lea Smith | Stunt Double |
| Pete Antico | Stunts |
| Gregory J. Barnett | Stunts |
| Peewee Piemonte | Stunts |
| Steven Lambert | Stunts |
