 | Irene Dunne als Anna Owens |
 | Rex Harrison als King Mongkut |
 | Linda Darnell als Tuptim |
 | Lee J. Cobb als Kralahome |
 | Gale Sondergaard als Lady Thiang |
 | Mikhail Rasumny als Alak |
 | Dennis Hoey als Sir Edward |
 | Tito Renaldo als Prince Chulalongkorn (as a boy) |
 | Richard Lyon als Louis Owens |
 | John Abbott als Phya Phrom |
 | Laurette Luez als Wife of King |
| Yvonne Rob |
| John Cromwell | Director |
| Talbot Jennings | Screenplay |
| Sally Benson | Screenplay |
| Arthur C. Miller | Director of Photography |
| Louis D. Lighton | Producer |
| William S. Darling | Art Direction |
| Lyle R. Wheeler | Art Direction |
| Margaret Landon | Book |
| Thomas Little | Set Decoration |
| Frank E. Hughes | Other |
| Harmon Jones | Editor |
| Bonnie Cashin | Costume Design |
| Ben Nye | Makeup Artist |
| Fred Sersen | Special Effects |
| Bernard Freericks | Sound |
| Roger Heman Sr. | Sound |
| Bernard Herrmann | Original Music Composer |
| Frances C. Richardson | Researcher |
