 | Andie MacDowell als Monique Lamont |
 | Daniel Sunjata als Win Garano |
 | Ashley Williams als Stump |
 | Annabeth Gish als Det. Delma Sykes |
 | Diahann Carroll als Nana |
 | Barclay Hope als Jessie Huber |
 | Zak Santiago als Roy |
 | Marcia Bennett als Kim Finlay |
 | Paula Boudreau als Mitzi |
 | Leslie Carlson als George Finlay |
 | Chad Connell als Toby Huber |
 | Dane DeHaan als Cal Tradd |
 | Lynne Deragon als Louisa Barber |
 | Joan Gregson als Vivian Finlay |
 | David Keeley als Howard Mather |
 | Darryn Lucio als Mark Holland |
 | Peter MacNeill als Gov. Crawley |
 | Carolyne Maraghi als Tracy |
| Shant Srabian als Farouk |
| Patricia Cornwell als Waitress |
 | Heather Hanson als Cal's Mother |
 | Edsson Morales als Jesus Baptista |
| Gilles Savard als Lamonth's Father |
 | Kristian Truelsen als Morgue Technician |
| Nathan McLeod als Jessie Huber at 16 (uncredited) |
| Patricia Cornwell | Novel |
| John Pielmeier | Teleplay |
| Tom McLoughlin | Director |
| Shana Landsburg | Casting |
| Michael Soos | Steadicam Operator |
| Dug Rotstein | Script Supervisor |
| Alwyn Kumst | Director of Photography |
| Ann Brodie | Key Makeup Artist |
| Colin Hoult | Camera Operator |
| Peter Nicolakakos | Set Decoration |
| Cliona Furey | Hair Department Head |
| Suzanne Angel | Dialogue Editor |
| Karen Bromley | Production Design |
| Richard Steele | Sound Effects Editor |
| Scott Ramsey | Visual Effects Supervisor |
| Noreen Landry | Costume Design |
| Chris Pellegrini | Property Master |
| Pierre Henry | First Assistant Director |
| Mark Friedgen | ADR Editor |
| Jamie Jones | Stunt Coordinator |
| Alistair Edwardson | Art Direction |
| Rocco Larizza | Special Effects Coordinator |
| Bonnie Sutherland | Costume Supervisor |
| Juliette Hagopian | Line Producer |
| Michael Innanen | Special Effects Coordinator |
| Damian Ganczewski | Producer |
| Charles Bornstein | Editor |
| Alan Zielonko | Boom Operator |
| Jonathan Pencharz | Production Coordinator |
| Christopher Ward | Original Music Composer |
| Rola Bauer | Co-Executive Producer |
| Patricia Cornwell | Executive Producer |
| John Pielmeier | Co-Executive Producer |
| Stanley M. Brooks | Executive Producer |
| Jim Head | Executive Producer |
| Jonas Bauer | Co-Executive Producer |
| Tim Halkin | Co-Executive Producer |
