 | Michaela Watkins als Judy Small |
 | Alicia Silverstone als Susan Howard |
 | Rob Corddry als Bob Howard |
 | Anna Pniowsky als Louise |
 | David Paymer als Dr. Edward Kingsley |
 | Aisha Tyler als Roxy |
 | Sarah Shahi als Annabelle |
 | Haley Joel Osment als Reed |
 | Dichen Lachman als Stern |
 | John Ross Bowie als Nick |
 | Ginger Gonzaga als Miranda |
 | Sunkrish Bala als Walter |
 | Erik Griffin als Principal Sykes |
 | Paris Bravo als Zooey |
 | Angela Oh als Dr. Smithson |
 | Marcelo Tubert als Dr. John |
 | Jack Axelrod als Dr. Cherbenko |
 | Brett Hoyle als James |
 | Flula Borg als Serge |
 | Craig Robert Young als Roger |
 | Gavin Leatherwood als Spit |
 | Chido Nwokocha als Policeman |
| William Teitler | Director |
| Nancy Doyne | Novel |
| Nancy Doyne | Screenplay |
| Rob Corddry | Executive Producer |
| David Leonard | Associate Producer |
| Rob Givens | Director of Photography |
| Emily Schweber | Casting |
| William Teitler | Producer |
| Brooks Kephart | Line Producer |
| Gina Resnick | Producer |
| Lisa Van Allsburg | Executive Producer |
| Kyle Heller | Executive Producer |
| Alison Sadler | Production Design |
| Sandra Leong | Associate Producer |
| Nathan Larson | Original Music Composer |
| David Leonard | Editor |
| Eric Cook | Co-Producer |
| Avy Kaufman | Casting |
| Brooks Kephart | Unit Production Manager |
| Aaron Steele-Nicholson | First Assistant Director |
| Clenét Verdi-Rose | Second Assistant Director |
| Kevin Huie | Second Assistant Director |
| Cole S. McKay | Stunt Coordinator |
| Patrick J. Statham | Stunt Double |
| Patrick J. Statham | Utility Stunts |
| Nick Fischer | First Assistant "A" Camera |
| Timothy Clarke | Additional First Assistant Camera |
| Matt Berbano | Second Assistant Camera |
| P.J. Russ | Loader |
| Tina Thorpe | Still Photographer |
| Michael A. Desmond | Still Photographer |
| Josh Hack | Drone Operator |
| Bartek Swiatek | Production Sound Mixer |
| Danny Maurer | Boom Operator |
| Melanie Lavender | Script Supervisor |
| Doran Meyers | Set Decoration |
| Sean Spillane | Leadman |
| Jeremy Kiddle | On Set Dresser |
| Travis Sullivan | Additional Set Dresser |
| Zach Takacs | Swing |
| Drew Crawle | Swing |
| Lukas Kozewski | Art Department Production Assistant |
| Brian Heinberg | Property Master |
| Molly Irelan | Costume Supervisor |
| Ysabel Riina | Costume Assistant |
| Chanèle Casaubon | Costumer |
| Jason Goodell | Gaffer |
| Dominic D'Astice | Best Boy Electric |
| Edward Scully | Electrician |
| Ryan 'Sparks' Lynch | Electrician |
| James Wilder Hancock | Key Grip |
| Danny Roy | Best Boy Grip |
| Adrian Estrella | Grip |
| Ana Lozano | Makeup Department Head |
| Kristina Goldberg | Assistant Makeup Artist |
| Porshawna Mosely | Hair Department Head |
| Marc Mapile | Assistant Hairstylist |
| James Wallace | Production Coordinator |
| Cesar Castillo | Production Coordinator |
| Serena Saylors | Production Secretary |
| Corinne Wedlake | Second Second Assistant Director |
| Judd Greener | Second Second Assistant Director |
| Madeline G. Phelps | Key Set Production Assistant |
| Andrew Pitts | Set Production Assistant |
| Artie Gonzales | Set Production Assistant |
| Frederick Gourgue | Set Production Assistant |
| Savannah Salter | Set Production Assistant |
| Blaine G. Houserman | Production Accountant |
| Marcy Brooks | Studio Teacher |
| Jade Jansen | Set Medic |
| Chris Serafin | Set Medic |
| Johnny Escobedo Jr. | Transportation Coordinator |
| Jacob Davidson | Driver |
| John Escobedo Sr. | Driver |
| Miroslav Kogosov | Driver |
| Nathan Krosley | Driver |
| Ron Quitevis | Driver |
| M'Saada Nia | Casting Associate |
| Jennifer Levy | Casting Associate |
| Leeba Zakharov | Casting Associate |
| Kris Hutchinson | Extras Casting |
| Ali Watters | Extras Casting |
| Lisa Wax | Location Manager |
| Mark Miskell | Location Assistant |
| Chicago Cruse | Security |
| Troy Joyner | Security |
| Alex Sandoval | Security |
| Henry Brown | Security |
| Reggie Hill | Security |
| Kelsey Rose | Craft Service |
| Nicole Klepper | Craft Service |
| Luis Cuevas | Assistant Editor |
| Isabel Teitler | Additional Editing |
| David M. Blum | VFX Artist |
| Adam Sonnenfeld | Digital Intermediate Producer |
| Patrick DeVine | Digital Intermediate Editor |
| Charles Leighton | Digital Intermediate Assistant |
| Andrew Francis | Digital Colorist |
| Bill Feightner | Imaging Science |
| Skip Lievsay | Supervising Sound Editor |
| Larry Zipf | Sound Effects Editor |
| Larry Zipf | Sound Re-Recording Mixer |
| Michael Feuser | Dialogue Editor |
| Eliza Paley | Dialogue Editor |
| Wyatt Sprague | Sound Effects Editor |
| Matthew Haasch | Foley Editor |
| Jay Peck | Foley Artist |
| Rachel Wardell | Assistant Sound Editor |
| Angela Asistio | Music Supervisor |
| Jordan L. Ross | Music Editor |
| Gerda Holmqvist | Musician |
| Illiana Larsdottir | Musician |
| Svala Gregorsson | Musician |
| Yuval Lion | Musician |
| Hans-Inge Magnusson | Musician |
| Sonja Labianca | Musician |
| Pete Hayes | Post Production Accountant |
| Sondra Locke | In Memory Of |
| Straw Weisman | Post Production Supervisor |
| Aggie Guerard Rodgers | Costume Designer |
