 | Dennis Miller als Rafe Guttman |
 | Erika Eleniak als Katherine Verdoux |
 | Angie Everhart als Lillith |
 | Chris Sarandon als Reverend Current |
 | Corey Feldman als Caleb Verdoux |
 | William Sadler als Mummy |
 | Aubrey Morris als McCutcheon |
 | Phil Fondacaro als Vincent Prather |
 | Kiara Hunter als Tamara |
| Leslie Ann Phillips als Patrice |
| Juliet Reagh als Tallulah |
 | Eli Gabay als Miguel |
 | Matt Hill als Reggie |
 | Eric Keenleyside als Noonan |
 | Kim Kondrashoff als Jenkins |
 | John Kassir als The Crypt Keeper (voice) |
 | Robert Munic als Zeke |
| Gary Starr als Jed |
 | Robin Douglas als Louise |
| Dorian Joe Clark als Jonas |
| Ravinder Toor als Bartender |
 | Robert Rozen als Rabbi Goldman |
 | Jennifer Jasey als Woman |
 | Heather Hanson als Babe |
| Sibel Thrasher als Gospel Singer |
 | Tom Pickett als Gospel Singer |
| Topaz Hasfal-Schou als Gospel Singer |
| Lovie Eli als Gospel Singer |
| Adam Boster als Patron (uncredited) |
 | Whoopi Goldberg als Hospital Patient (uncredited) |
 | Kate McIntyre als Chubbie O'Toole (uncredited) |
 | Tobias Mehler als Boy in Bordello (uncredited) |
 | Iva Franks-Singer als Werewolf (uncredited) |
| Gilbert Adler | Director |
| Gilbert Adler | Screenplay |
| Gilbert Adler | Producer |
| Chris Boardman | Original Music Composer |
| Danny Elfman | Original Music Composer |
| Tom Priestley Jr. | Director of Photography |
| Stephen Lovejoy | Editor |
| A L Katz | Screenplay |
| Bob Gale | Story |
| Robert Zemeckis | Story |
| William M. Gaines | Comic Book |
| Victoria Burrows | Casting |
| Gregory Melton | Production Design |
| Sheila Haley | Art Direction |
| Joanna King | Art Direction |
| Annmarie Corbett | Set Decoration |
| Rose Marie McSherry | Set Decoration |
| Trish Keating | Costume Design |
| Michelle Gasque | Art Department Coordinator |
| Tim Storvick | Special Effects Coordinator |
| Karl Formander | Animation |
| Terry Sonderhoff | Special Effects Supervisor |
| Sandi Nielsen | Casting |
| Heidi Ross | Assistant Costume Designer |
| Carolyn Bahen | Assistant Costume Designer |
| Julie MacDonald | Set Costumer |
| Helena Lea | Music Editor |
| Lara Fox | Script Supervisor |
| Ian C. Ballard | Key Hair Stylist |
| Victoria Down | Makeup Artist |
| Joel Silver | Executive Producer |
| Walter Hill | Executive Producer |
| David Giler | Executive Producer |
| A L Katz | Co-Producer |
| Alexander B. Collett | Co-Producer |
| Dan Cracchiolo | Associate Producer |
| Richard Donner | Executive Producer |
| Richard Mirisch | Associate Producer |
| Robert Zemeckis | Executive Producer |
| Tony Acosta Jr. | Special Effects Makeup Artist |
| David P. Barton | Special Effects Makeup Artist |
| Mitchell J. Coughlin | Special Effects Makeup Artist |
| Richard Maybery | Special Effects Makeup Artist |
| David Miner Jr. | Special Effects Makeup Artist |
| Doug Morrow | Special Effects Makeup Artist |
| Ron Pipes | Special Effects Makeup Artist |
| Shaun Smith | Special Effects Makeup Artist |
| Brian Van Dorn | Special Effects Makeup Artist |
| Bill Zahn | Special Effects Makeup Artist |
| Christopher Allen Nelson | Makeup Effects Designer |
| Scott Nimerfro | Associate Producer |
| Donna Evans | Stunts |
| Melissa R. Stubbs | Stunts |
| Scott Wilder | Stunt Coordinator |
| Tim A. Davison | Stunt Coordinator |
| Shane Dixon | Stunt Coordinator |
| Troy Brown | Stunts |
| Dorothy Fehr | Stunts |
| Maria R. Kelly | Stunts |
| Fiona Roeske | Stunts |
| Michael Langlois | Stunts |
| David Jacox | Stunt Coordinator |
| Sandy Berumen | Stunts |
| Barbara C. Adside | Stunts |
