 | Jennifer Aniston als Claire Bennett |
 | Adriana Barraza als Silvana |
 | Anna Kendrick als Nina Collins |
 | Sam Worthington als Roy Collins |
 | Mamie Gummer als Bonnie |
 | Felicity Huffman als Annette |
 | William H. Macy als Leonard |
 | Chris Messina als Jason Bennett |
 | Lucy Punch als Nurse Gayle |
 | Britt Robertson als Becky |
 | Paula Cale als Carol |
 | Ashley Crow als Stephanie |
 | Manuel Garcia-Rulfo als Arturo |
 | Camille Guaty als Tina |
 | Allen Maldonado als Buddy |
 | Camille Mana als Nurse Salazar |
 | Julio Oscar Mechoso als Pharmacist |
 | Evan O'Toole als Casey Collins |
| Lizzie Peet als Gail |
 | Pepe Serna als Nuncio |
 | Misty Upham als Liz |
 | Rose Abdoo als Innocencia |
 | Alma Martinez als Irma |
 | Andrew Elvis Miller als Border Patrol Officer |
| Louie Novoa als Waiter |
 | Laura Putney als Clinic Worker |
| Robert Zimiga als Border Patrol Officer #2 |
| Daniel Barnz | Director |
| Michelle Harrison | Editor |
| Joseph T. Garrity | Production Design |
| Karyn Wagner | Costume Design |
| Patrick Tobin | Screenplay |
| Rachel Morrison | Director of Photography |
| Kristina Boden | Editor |
| Shyam Madiraju | Executive Producer |
| Wayne Marc Godfrey | Co-Producer |
| Stephanie Caleb | Co-Producer |
| Mary Vernieu | Casting |
| Ben Barnz | Producer |
| Courtney Solomon | Producer |
| Kristin Hahn | Producer |
| Mark Canton | Producer |
| Scott Karol | Co-Producer |
| Jennifer Aniston | Executive Producer |
| Elizabeth Destro | Co-Producer |
| Lindsay Graham Ahanonu | Casting |
| Babak Eftekhari | Associate Producer |
| Angela Levin | Makeup Department Head |
| Shant Jordan | Visual Effects Supervisor |
| Chad Cohlmia | Gaffer |
| Terrie Velazquez Owen | Hairstylist |
| Myron Nettinga | Supervising Sound Editor |
| Jason Oldak | Additional Camera |
| Lisa Son | Set Decoration |
| Donna Casey-Aira | Costume Supervisor |
| Brian Burgoyne | Camera Operator |
| Rod Ortega | Hairstylist |
| Desne J. Holland | Makeup Artist |
| Ronit Ravich-Boss | Script Supervisor |
| Alex Hunter | Art Department Coordinator |
| Karen Ballard | Still Photographer |
| James Gallivan | Sound Effects Editor |
| Stephen W. Pugh | Visual Effects Producer |
| Paula Avazian | Set Costumer |
| Myron Nettinga | Sound Re-Recording Mixer |
| Tom Boyd | Underwater Camera |
| Gary Monak | Special Effects Coordinator |
| Jay Nierenberg | Sound Effects Editor |
| Tony Rivetti Jr. | Still Photographer |
| Brittany Bradford | Art Direction |
| John Sievert | Foley |
| Susan Kurtz | Dialogue Editor |
| Mike Szakmeister | Dialogue Editor |
| Christophe Beck | Music |
