 | Renée Zellweger als Emily Jenkins |
 | Jodelle Ferland als Lillith Sullivan |
 | Ian McShane als Detective Mike Barron |
 | Bradley Cooper als Douglas J. Ames |
 | Adrian Lester als Wayne |
 | Kerry O'Malley als Margaret Sullivan |
 | Callum Keith Rennie als Edward Sullivan |
 | Cynthia Stevenson als Nancy |
 | Alexander Conti als Diego |
 | Philip Cabrita als Javier |
 | Vanesa Tomasino als Javier's Wife |
 | Mary Black als Custody Judge |
| Domenico D'Ambrosio als Domenico D'Ambrosio |
 | Benita Ha als Therapist |
| J. Winston Carroll als Judge |
 | Michael Bean als Co-Worker |
 | Lesley Ewen als Co-Worker |
| David Patrick Green als Chief Psychiatrist |
 | Dee Jay Jackson als Bus Driver |
| Taya Calicetto als Young Emily |
 | Alisen Down als Emily's Mother |
 | Darryl Quon als Inmate |
| Suzanne Bastien als Nurse |
| Jane Braithwaite als Nurse |
 | Colin Lawrence als Police Sergeant |
| Fran Gebhard als Coordinator |
 | Dagmar Midcap als News Anchor |
 | Bill Mondy als Interviewer |
 | Andrew Airlie als Doctor |
 | Sarah-Jane Redmond als Barron's Wife |
 | Charles Zuckermann als Demon Person |
| Yvonne Valdez als Mrs. Lynch |
| Paul Duchart als Priest |
 | Daniel Bacon als Businessperson |
| Darren E. Scott als Young Cop |
 | Dalias Blake als Detention Center Cop |
 | Phillip Mitchell als Lead Guard |
 | Fulvio Cecere als Fire Marshall |
| Sarah Halley Finn | Casting |
| Kevin Misher | Producer |
| Michl Britsch | Original Music Composer |
| Randi Hiller | Casting |
| Steve Golin | Producer |
| Ray Wright | Writer |
| Alix Madigan | Producer |
| Scott Thaler | Producer |
| Lisa Bruce | Producer |
| Mark Goldblatt | Editor |
| Monique Prudhomme | Costume Design |
| Christian Alvart | Director |
| Hagen Bogdanski | Director of Photography |
| Carie Wallis | Art Department Coordinator |
| Erik Liles | Visual Effects Supervisor |
| Ross Dempster | Art Direction |
| Chris Watts | Visual Effects Supervisor |
| Marny Eng | Stunt Coordinator |
| Julia Frittaion | Unit Publicist |
| Andrea French | Set Decoration |
| Thomas Nittmann | Visual Effects Producer |
| Chris Roff | Visual Effects Producer |
| Lisa Jaime | Music Editor |
| Joshua Cordes | Animation Supervisor |
| Kimberly French | Still Photographer |
| Danny McWilliams | Location Manager |
| John O'Toole | Transportation Coordinator |
| Daniel J. Leahy | Sound Re-Recording Mixer |
| Steven Hodgson | Visual Effects Supervisor |
| Edson Williams | Visual Effects Supervisor |
| Craig Calvert | CG Supervisor |
| Steve Reintjes | Scenic Artist |
| Travis J. Brooks | Greensman |
| Ronald Eng | Sound Designer |
| Doug Jackson | Sound Effects Editor |
| Paul Furminger | Visual Effects Editor |
| Peter Grace | Construction Coordinator |
| Collette Nunes | Visual Effects Editor |
| John Burke | Assistant Art Director |
| Karl Herrmann | Camera Operator |
| Steve Ansell | First Assistant Editor |
| Jason Claridge | Lead Painter |
| Harvey LaRocque | Camera Operator |
| Ronald Eng | Supervising Sound Editor |
| Bob Comer | Special Effects Coordinator |
| Shauna Bryn | Visual Effects Producer |
| David Crone | Steadicam Operator |
| John Willett | Production Design |
| David Sosalla | Visual Effects Supervisor |
| Jim Van Dijk | Steadicam Operator |
| Danielle de Smit | Script Supervisor |
| Wayne Bennett | Production Manager |
| Steve Tushar | Sound Effects Editor |
| Grant Swain | Property Master |
| Susan Boyd | Assistant Hairstylist |
| Rebecca Lee | Assistant Makeup Artist |
| Nancy Steyns | Hairstylist |
| Donna Bis | Hairstylist |
| Lisa Love | Makeup Artist |
| Brad Wilder | Makeup Artist |
| Toby Lindala | Special Effects Makeup Artist |
| Patrice Leung | First Assistant Director |
| Tracey Poirier | Second Assistant Director |
| Warren Hanna | Second Assistant Director |
| Scott J. Ateah | Second Unit Director |
| Greg Milton | Second Unit First Assistant Director |
| Janice Chiu | Art Department Assistant |
| Eric Partridge | Assistant Property Master |
| Nevin Swain | Assistant Property Master |
| Mike Sorochuk | Construction Foreman |
| Mike Lilley | Graphic Designer |
| Darryl Tifenbach | Lead Painter |
| Herminio Kam | Paint Coordinator |
| Mark N. Tompkins | Painter |
| Trevor Cole | Set Dresser |
| Miya Dube | Set Dresser |
| Shelley Surette | Set Dresser |
| Hans Bjerno | Aerial Director of Photography |
| Paul Bougie | Assistant Chief Lighting Technician |
| Katie Matheson | Camera Trainee |
| Andrew Capicik | Camera Trainee |
| Peter G. Capadouca | Chief Lighting Technician |
| Gil Forrester | Dolly Grip |
| Mike West | Dolly Grip |
| Zane Rossouw | Dolly Grip |
| Dustin Allen | Electrician |
| Bill Dawson | Electrician |
| Patrick Stepien | First Assistant Camera |
| Dillard Brinson | First Company Grip |
| Randy Stamhuis | First Company Grip |
| Mike Stroman | Generator Operator |
| Donnie Armstrong | Grip |
| Ken Hemphill | Grip |
| Aaron Wik | Grip |
| Jeff Bonny | Rigging Grip |
| Michael Lemmers | Rigging Grip |
| Artino Ahmadi | Second Assistant Camera |
| Rick Stadder | Second Company Grip |
| J. Norman Earle | Second Company Grip |
| Karl Herrmann | Second Unit Director of Photography |
| Ian Seabrook | Underwater Director of Photography |
| Nancy Bryant | Assistant Costume Designer |
| Christine Coutts | Costume Supervisor |
| Paul Lavigne | Costume Supervisor |
| Angela Bright | Costumer |
| Summer Eves | Costumer |
| Caitlin McKenna | ADR Voice Casting |
| Heike Brandstatter | Casting |
| Coreen Mayrs | Casting |
| Taylor Jenkins | Casting Assistant |
| Leah Nelson | Casting Assistant |
| Tamara Hunter | Casting Associate |
| Trica Thompson | Casting Associate |
| Yvonne Valdez | Additional Editor |
| Jason Dale | Assistant Editor |
| Stephen R. Sheridan | Color Timer |
| John Brandon | Dailies Operator |
| Mary Nelson-Duerrstein | Negative Cutter |
| Bob Baron | ADR Mixer |
| Dana LeBlanc Frankley | Assistant Sound Editor |
| Jon Lavender | Boom Operator |
| Cameron Foodikoff | Cableman |
| Robin Harlan | Foley Artist |
| Sarah Monat | Foley Artist |
| Randy Singer | Foley Mixer |
| Willard Overstreet | Foley Supervisor |
| Pete Dawood | Sound Editor |
| Darren Brisker | Sound Mixer |
| Gary Summers | Sound Re-Recording Mixer |
| David A. Cohen | Supervising ADR Editor |
| Robert Troy | Supervising Dialogue Editor |
| Luis Carlos Aguilar | Animation |
| Chris Derochie | Animation |
| Agata Matuszak | Animation |
| Mark Pullyblank | Animation |
| Greg Winhall | Animation |
| Michael Amasio | CG Artist |
| Bryan Davies | CG Artist |
| Sally Goldberg | CG Artist |
| Mark Harrison | CG Artist |
| Hans Heymans | CG Artist |
| Amy Lee | CG Artist |
| Dan Mayer | CG Artist |
| Peter Scott | CG Artist |
| Karl Sisson | CG Artist |
| Mark Stewart | CG Artist |
| Chad L. Fox | CG Artist |
| Karl Rogovin | CG Supervisor |
| Bill Kunin | Compositing Supervisor |
| Abel Milanes | Compositing Supervisor |
| Bob Neve | Aerial Coordinator |
| Kathleen Whelan | Production Coordinator |
| Mark Aisbett | Stunts |
| Ed Anders | Stunts |
| Doug Chapman | Stunts |
| Lauro David Chartrand-DelValle | Stunts |
| Dean Choe | Stunts |
| Laura Lee Connery | Stunts |
| Mike Crestejo | Stunts |
| Crystal Dalman | Stunts |
| Mike Desabrais | Stunts |
| Duane Dickinson | Stunts |
| Ryan Ennis | Stunts |
| Caroline Field | Stunts |
| Corry Glass | Stunts |
| Tom Glass | Stunts |
| Rob Hayter | Stunts |
| Kim Howey | Stunts |
| Ernie Jackson | Stunts |
| David Jacox | Stunts |
| Jon Kralt | Stunts |
| Michael Langlois | Stunts |
| Terrance Leigh | Stunts |
| John MacDonald | Stunts |
| Gaston Morrison | Stunts |
| Scott Nicholson | Stunts |
| Gerald Paetz | Stunts |
| Rick Pearce | Stunts |
| Matt Phillips | Stunts |
| Justin Sain | Stunts |
| Darryl Scheelar | Stunts |
| Kimani Ray Smith | Stunts |
| Clay Virtue | Stunts |
| Bryan Arenas | Dolby Consultant |
| David Halliday | Transportation Captain |
| Shelley Maclean | Visual Effects Editor |
| Yasamin Ismaili | Visual Effects Coordinator |
| Chris Wells | CG Supervisor |
| Joshua Cordes | Animation Supervisor |
