 | Keanu Reeves als John Constantine |
 | Rachel Weisz als Angela Dodson / Isabel Dodson |
 | Shia LaBeouf als Chas Kramer |
 | Djimon Hounsou als Midnite |
 | Max Baker als Beeman |
 | Pruitt Taylor Vince als Father Hennessy |
 | Gavin Rossdale als Balthazar |
 | Tilda Swinton als Gabriel |
 | Peter Stormare als Lucifer |
 | Jesse Ramirez als Scavenger |
 | José Zúñiga als Detective Weiss |
 | April Grace als Dr. Leslie Archer |
 | Larry Cedar als Vermin Man |
 | Francis Guinan als Father Garret |
 | Suzanne Whang als Mother |
 | Jhoanna Trias als Possessed Girl |
 | Alice Lo als Old Woman |
 | Nicholas Downs als Church Attendant |
 | Tanoai Reed als Midnite Bouncer |
| Quinn Buniel als 10 Year-Old Constantine |
 | Ann Ryerson als Old Woman on Bus |
| Stephanie Fabian als Molly's Server |
| Connor Dylan Wryn als Teenage Constantine |
 | Laz Alonso als Morgue Security Guard |
 | Jeremy Ray Valdez als Liquor Store Clerk Nico |
| Jose Molina als Scavenger #2 |
 | Barbara Pilavin als Old Woman on Bus (Demon) |
 | C.W. Pyun als Korean Man |
 | Sharon Omi als Female Tenant |
| Edward J. Rosen als Liquor Store Clerk |
| John Gipson als Smoking Man |
| Roberto Kawata als Police Officer |
 | Michelle Monaghan als Ellie (uncredited) |
 | R.A. Rondell als Man in Jeep (uncredited) |
 | Chad Stahelski als Demon in Hospital (uncredited) |
| Francis Lawrence | Director |
| Kevin Brodbin | Screenplay |
| Frank A. Cappello | Screenplay |
| Michael Uslan | Producer |
| Erwin Stoff | Producer |
| Lauren Shuler Donner | Producer |
| Benjamin Melniker | Producer |
| Akiva Goldsman | Producer |
| Gilbert Adler | Executive Producer |
| Michael Aguilar | Executive Producer |
| Klaus Badelt | Original Music Composer |
| Brian Tyler | Original Music Composer |
| Philippe Rousselot | Director of Photography |
| Wayne Wahrman | Editor |
| Denise Chamian | Casting |
| Naomi Shohan | Production Design |
| David Lazan | Art Direction |
| Douglas A. Mowat | Set Decoration |
| Louise Frogley | Costume Design |
| Kevin Brodbin | Story |
| Ve Neill | Makeup Department Head |
| Lorenzo di Bonaventura | Producer |
| Cherylanne Martin | Co-Producer |
| Robert Elhai | Orchestrator |
| Susan Hegarty | Dialect Coach |
| Willie D. Burton | Sound Mixer |
| Steve Artmont | Makeup Artist |
| Barney Burman | Makeup Artist |
| Robin Slater | Makeup Artist |
| Ginger Damon | Hairstylist |
| Matthew J. Birch | Production Supervisor |
| Carla S. Nemec | Art Department Coordinator |
| Robert Fechtman | Assistant Art Director |
| Jason Sweers | Assistant Art Director |
| Suzan Wexler | Assistant Art Director |
| Joe Ondrejko | Construction Coordinator |
| William Gideon | Construction Foreman |
| William J. Law III | Set Designer |
| Steven Schwartz | Set Designer |
| Stan Tropp | Set Designer |
| Cuitlahuac Morales Velazquez | Sculptor |
| Skip Lievsay | Supervising Sound Editor |
| Jeremy Peirson | Sound Designer |
| Charles Maynes | Sound Designer |
| Craig Berkey | Sound Effects Editor |
| John P. Fasal | Sound Effects Editor |
| Stephen Hunter Flick | Sound Effects Editor |
| Patricio A. Libenson | Sound Effects Editor |
| James Morioka | Sound Effects Editor |
| David E. Campbell | Sound Re-Recording Mixer |
| John T. Reitz | Sound Re-Recording Mixer |
| Allen Hall | Special Effects Coordinator |
| Simon Allen | Animation Supervisor |
| Mark Shoaf | CG Supervisor |
| Randy Bricker | Visual Effects Editor |
| Michael L. Fink | Visual Effects Supervisor |
| Craig Hayes | Visual Effects Supervisor |
| Ian Hunter | Visual Effects Supervisor |
| Greg Juby | Visual Effects Supervisor |
| David Lingenfelser | Visual Effects Supervisor |
| Colin Strause | Visual Effects Supervisor |
| Greg Strause | Visual Effects Supervisor |
| Janet Yale | Visual Effects Producer |
| Denise Davis | Visual Effects Producer |
| Jason Heapy | Visual Effects Producer |
| Amy Hollywood Wixson | Visual Effects Producer |
| Donna Langston | Visual Effects Producer |
| Tiffany Smith | Visual Effects Producer |
| Ann Podlozny | Visual Effects Producer |
| Michael Meagher | Visual Effects Producer |
| Demetrius Leal | Visual Development |
| R.A. Rondell | Stunt Coordinator |
| Jack English | Gaffer |
| Timothy Roarke | Camera Operator |
| Michael-Ryan Fletchall | Camera Operator |
| Mark La Bonge | Camera Operator |
| Mark La Bonge | Steadicam Operator |
| Seth Kotok | Additional Camera |
| Jarred Waldron | Gaffer |
| Juan Morse | Gaffer |
| Dennis J. Lootens | Rigging Gaffer |
| Jeff Cutter | Additional Photography |
| Jeff Cutter | Still Photographer |
| Richard Foreman Jr. | Still Photographer |
| Marina Marit | Set Costumer |
| Bob Moore Jr. | Set Costumer |
| Nancy Smytka | Set Costumer |
| Robert Q. Mathews | Costume Supervisor |
| Gordon Antell | First Assistant Editor |
| Daryl B. Kell | Music Editor |
| Gary Krause | Music Editor |
| Joe Lisanti | Music Editor |
| Bernice Culbertson | Transportation Coordinator |
| Dan Marrow | Transportation Coordinator |
| Craig Lietzke | Picture Car Coordinator |
| Molly Allen | Location Manager |
| Kristin Dehnert | Location Manager |
| Judith Jennings | Studio Teachers |
| Douglas S. McClintock II | Location Manager |
| Paulette Osorio | Unit Publicist |
| Jackie Brady Baugh | Production Accountant |
| Brooks Baldwin | Dialect Coach |
| Chuck Duke | Animation |
| Howard R. Campbell | Lighting Technician |
| Josh McLaglen | Co-Producer |
| Candace Neal | Key Hair Stylist |
| Karin Silvestri | Stunts |
| Rob Cunningham | Boom Operator |
| Lindsey Gary | Art Department Assistant |
| Constantine Sekeris | Conceptual Design |
| Leigh-Alexandra Jacob | Lead Painter |
| Charles Kern | Painter |
| Harald Belker | Production Illustrator |
| Michael Cassidy | First Assistant Camera |
| C. Alan Rawlins Sr. | Key Grip |
| Hans Bjerno | Aerial Director of Photography |
| Susan Germaine | Hair Department Head |
| Wolfram de Marco | Additional Music |
| Daragh Byrne | Carpenter |
| Robert Lamkin | Chef |
| Raymond Bulinski | Craft Service |
| Randy Goux | Digital Effects Supervisor |
| Mark Valdez | Driver |
| Laraine Moniz | Post Production Assistant |
| Ilyse A. Reutlinger | Post Production Supervisor |
| Bobby Mara | Propmaker |
| Lance Mancuso | Set Medic |
| Elizabeth C. Camp | Set Production Assistant |
| Rob McCabe | Stand In |
| Kenny Alexander | Stunts |
| Eric Putz | Telecine Colorist |
| Randy Burke | Transportation Captain |
| Chad Moore | Transportation Co-Captain |
| Cherylanne Martin | Unit Production Manager |
| Luciano Blotta | Video Assist Operator |
| Dave Hussey | Color Timer |
| Brian Crane | Best Boy Electric |
| Paul Postal | Electrician |
| Haskell Friedman | Lighting Artist |
| John S. Campbell | Rigging Grip |
| Scout Masterson | Casting Associate |
| Mark Scoon | Executive In Charge Of Production |
| Ralph Bertelle | Production Coordinator |
| Brian Brecht | Production Manager |
| Greg Abbas | Researcher |
| Sarah Bourgeois | Assistant Sound Editor |
| Jared Rosen | 24 Frame Playback |
| Anthony Leonardi III | Creature Design |
| John R.A. Benson | Digital Compositors |
| Nathan Abbot | I/O Supervisor |
| James Reedy | Special Effects Supervisor |
| Aaron Cohen | Visual Effects |
| Mark Edwards | Visual Effects Coordinator |
| Matt Heimlich | Mechanical Designer |
| Enfys Dickinson | Creative Producer |
| Gregg Rudloff | Sound Re-Recording Mixer |
| Tim Rigby | Stunts |
| Susan Dudeck | Dialogue Editor |
| Ulrika Akander | Dialogue Editor |
| Neal Norton | Second Unit Director of Photography |
| Kirk Corwin | Property Master |
| Mark Johnston | Sound Recordist |
| Jamie Rama | Costume Illustrator |
| Sandra Bojin-Sedlik | Costumer |
| Valerie T. O'Brien | Key Costumer |
| Rick Kelly | Second Assistant Director |
| Maria Battle Campbell | Second Second Assistant Director |
| Michael L. Fink | Second Unit Director |
| Andrew M. Siegel | Assistant Property Master |
| Kent Demaine | Creative Director |
| Joey Genitempo | Set Painter |
| Trevor Goring | Storyboard Artist |
| Paul Luther Jackson | Swing |
| Joe Dorn | ADR Editor |
| Eric Gotthelf | ADR Mixer |
| Joel Dougherty | First Assistant Sound Editor |
| Michael J. Broomberg | Foley Artist |
| Mary Jo Lang | Foley Mixer |
| John Joseph Thomas | Foley Supervisor |
| Pamela Elliott | Special Effects Assistant |
| Lawrence Decker | Special Effects Technician |
| Ryan Hopkins | Visual Effects Technical Director |
| Casey O'Neill | Stunt Double |
| Mike Massa | Stunt Driver |
| Xiomara Comrie | Assistant Camera |
| Riko Schatke | Best Boy Grip |
| Deborah Thomas | Data Wrangler |
| Darryl Humber | Dolly Grip |
| Kelly Diehl | Libra Head Technician |
| Jim Charmatz | Character Designer |
| Dovi Anderson | Lead Animator |
| Caitlin McKenna | ADR Voice Casting |
| Dena Berman | Casting Assistant |
| Bronwyn Shields | Assistant Editor |
| Nicholas Hasson | Digital Intermediate Editor |
| Erik Rogers | Digital Intermediate Producer |
| Mo Henry | Negative Cutter |
| Rachel Swenson | Assistant Location Manager |
| Brian Tyler | Conductor |
| Jeffrey Pollack | Music Consultant |
| James Babineaux | Assistant Chief Lighting Technician |
| J. Elizabeth Ingram | Assistant Production Coordinator |
| John Cassella | CG Artist |
| Dan Cayer | Compositing Supervisor |
| Kathy Liska | Executive Assistant |
| Tracy Dixon | Extras Casting |
| Vesper Burnett | Extras Casting Assistant |
| Chad Stahelski | Fight Choreographer |
| Donald Fly | General Manager |
| Alonzo Ruvalcaba | Head of Production |
| Robert J. Reilly | Key Rigging Grip |
| Michael Lagnese | Key Set Production Assistant |
| Chris Paizis | Matchmove Supervisor |
| Jamie Baxter | Matte Painter |
| Taffy Schweickhardt | Payroll Accountant |
| Lee Hahn | Production Assistant |
| Michael P. Twombly | Production Secretary |
| Frank Toro | Pyrotechnician |
| Kane Brassington | Rotoscoping Artist |
| Kami Calevro | Second Assistant Accountant |
| April Kelley | Camera Loader |
| Mike Justus | Utility Stunts |
| A Perfect Circle | Music |
| Rich Andrade | Set Dresser |
| Shane Mahan | Makeup Supervisor |
| Josh McLaglen | First Assistant Director |
| Darin Rivetti | Second Unit First Assistant Director |
| Zack Heath | Art Department Assistant |
| Brian Johnson | Art Department Assistant |
| Tom Hammock | Art Department Assistant |
| Frank Musitelle | Greensman |
| Ray Maxwell | Propmaker |
| Jim Meyer | Propmaker |
| Fred O'Connor | Propmaker |
| Susannah Carradine | Assistant Set Decoration |
| Paul Detlefson | Set Dresser |
| James L. Eddy | Set Dresser |
| Steven Ladish | Set Dresser |
| David Loitz | Set Dresser |
| Eric Ramirez | Set Dresser |
| Brett C. Smith | Set Dresser |
| Pamela Rittelmeyer | Assistant Camera |
| Bryan Booth | Electrician |
| Erik A. Erichsen | Electrician |
| Michael Franco | Electrician |
| Gene Hara | Electrician |
| Gary Lowrance | Electrician |
| David A. Parks | Electrician |
| Stephen Thorp | Electrician |
| Eric Budlong | Grip |
| R. Dana Harlow | Grip |
| Pat O'Mara | Grip |
| Chis Rountree | Grip |
| Andrew Taylor | Key Grip |
| Huston Beaumont | Rigging Grip |
| Michael Dronge | Rigging Grip |
| Eddie G. Gutierrez | Rigging Grip |
| Thomas E. Lee | Rigging Grip |
| Vince Onken | Rigging Grip |
| Frank R. Sims | Rigging Grip |
| Bryan Fletchall | Techno Crane Operator |
| Ellen Falguiere | Costumer |
| Monica Haynes | Costumer |
| Valerie Laven-Cooper | Costumer |
| Catherine Liebig | Costumer |
| Nina Padovano | Costumer |
| Garet Reilly | Key Costumer |
| Richard Schoen | Key Costumer |
| Teressa Hill | Hairstylist |
| Joel Harlow | Key Makeup Artist |
| Janice Kavanagh | Makeup Artist |
| John Rosengrant | Makeup Supervisor |
| Christopher Allen Nelson | Special Effects Makeup Artist |
| Stan Winston | Special Effects Makeup Artist |
| Rick Glenn | Animation Supervisor |
| Joe Henke | Animation Supervisor |
| Gary Abrahamian | Lead Animator |
| William Groebe | Animation |
| Brian Mendenhall | Animation |
| James Straus | Animation |
| Jason Armstrong | Animation |
| James W. Brown | Animation |
| Michael Kitchen | Animation |
| Todd Labonte | Animation |
| Amy Garback | CG Artist |
| Eric Pender | CG Artist |
| Chris Ryan | CG Artist |
| Kyle Yamamoto | CG Artist |
| John Stillman | Compositing Supervisor |
| Sean O'Connor | Compositing Supervisor |
| David 'Grue' Debry | CG Supervisor |
| Gregory D. Liegey | Digital Effects Supervisor |
| Christopher Warren | VFX Director of Photography |
| Joshua Cordes | Lead Animator |
| Joel Sevilla | Lead Animator |
| Ron Crabb | Matte Painter |
| Yoshiya Yamada | Modelling Supervisor |
| John 'JD' Daniel | Modeling |
| Dan Dixon | Modeling |
| Christopher J. Eng | Modeling |
| Jericho Green | Modeling |
| Jose Samson | Modeling |
| Paul Zinnes | Modeling |
| Ross Nakamura | Rotoscoping Artist |
| Nicholas Brooks | VFX Artist |
| Scott Kinsey | VFX Artist |
| Ryan Lastimosa | VFX Artist |
| Brian Ducharme | VFX Artist |
| Chris Haney | Visual Effects |
| Anthony Lucero | Visual Effects |
| Patrick Phillips | Visual Effects |
| Robert Spurlock | Visual Effects |
| Chris F. Moore | Visual Effects |
| Beth Howe | Visual Effects Coordinator |
| Kristy King | Visual Effects Coordinator |
| Julia Neighly | Visual Effects Coordinator |
| Stephanie C. Lee | Visual Effects Coordinator |
| Mark Edwards | Visual Effects Coordinator |
| Adam Lisagor | Visual Effects Coordinator |
| James D. Tittle | Visual Effects Coordinator |
| Kevin Romond | Visual Effects Technical Director |
| Csaba László Eröss | Special Effects Assistant |
| Ante Dugandzic | Special Effects Technician |
| Jack Jennings | Special Effects Technician |
| Michael Kay | Special Effects Technician |
| Jeff Khachadoorian | Special Effects Technician |
| Jeff Ogg | Special Effects Technician |
| Parry Willard | Special Effects Technician |
| Thomas J. O'Connell | ADR Mixer |
| Troy Porter | ADR Mixer |
| Michael J. Benavente | ADR Supervisor |
| Greg ten Bosch | Assistant Sound Editor |
| John Roesch | Foley Artist |
| Alyson Dee Moore | Foley Artist |
| Janusz Tokarzewski | Sound Engineer |
| Natasha Delahunt | Production Assistant |
| Jack Dubnicek | Production Assistant |
| Juliana FauntLeRoy | Production Assistant |
| Zachary Kamen | Production Assistant |
| Gregg Kawecki | Production Assistant |
| Nate Ruegger | Production Assistant |
| Chris Hall | Visual Effects Coordinator |
| Armen Ksajikian | Musician |
| David Leitch | Stunts |
| Jamie Delano | Comic Book |
| Garth Ennis | Comic Book |
| Alan Moore | Characters |
| J.J. Perry | Stunts |
| Henry Kingi | Stunts |
| Bob Brown | Stunts |
| Chris Palermo | Stunts |
| Heidi Moneymaker | Stunts |
| Clay Cullen | Stunts |
| Erik Rondell | Stunts |
| Gloria O'Brien | Stunts |
| Jeremy Fry | Stunts |
