 | Mia Wasikowska als Edith Cushing |
 | Jessica Chastain als Lady Lucille Sharpe |
 | Tom Hiddleston als Sir Thomas Sharpe |
 | Charlie Hunnam als Dr. Alan McMichael |
 | Jim Beaver als Carter Cushing |
 | Burn Gorman als Holly |
 | Leslie Hope als Mrs. McMichael |
 | Jonathan Hyde als Ogilvie |
 | Doug Jones als Edith's Mother / Lady Sharpe |
 | Bruce Gray als Ferguson |
 | Emily Coutts als Eunice McMichael |
 | Alec Stockwell als Finlay |
| Brigitte Robinson als Secretary Jane |
| Gillian Ferrier als Society Girl |
 | Tamara Hope als Society Girl |
 | Kimberly-Sue Murray als Society Girl |
 | Sofia Wells als Young Edith |
 | Joanna Douglas als Maid Annie |
 | Bill Lake als Coroner |
 | Jim Watson als Shipping Agent |
 | Javier Botet als Enola / Margaret / Pamela |
| Peter Spence als Manager |
 | Danny Waugh als Club Attendant |
 | Sean Hewitt als Reverend |
| William Healy als Young Alan |
| Matia Jackett als Young Eunice |
 | Karen Glave als Maid |
 | Khadijah Roberts-Abdullah als Maid |
| John Carter Craig als Patient |
 | Martin Julien als Postal Clerk |
 | Brian Kaulback als Vendor |
| Richard Kerr als Vendor |
| Shane McPherson als Vendor |
| Tim Blake als Reverend |
| Thomas Dorey als Architect |
| Erik Bauersfield als Additional Voices (voice) |
| Joan Washington als Additional Voices (voice) |
| Beatrice Basso als Additional Voices (voice) |
 | Mitzi McCall als Additional Voices (voice) |
 | Susanne Blakeslee als Additional Voices (voice) |
 | Drew Davis als Additional Voices (voice) |
 | T.J. McGibbon als Additional Voices (voice) |
| Anneliese Goldman als Additional Voices (voice) |
 | Jenna Weir als Additional Voices (voice) |
| Amanda Smith als Beatrice (uncredited) |
 | Laura Waddell als Pamela Upton (uncredited) |
| Guillermo del Toro | Director |
| Bernat Vilaplana | Editor |
| Matthew Robbins | Writer |
| Callum Greene | Producer |
| Devin Roth | Score Engineer |
| Dan Laustsen | Director of Photography |
| Kate Hawley | Costume Design |
| Thomas E. Sanders | Production Design |
| Fernando Velázquez | Original Music Composer |
| Thomas Tull | Producer |
| Guillermo del Toro | Writer |
| Jon Jashni | Producer |
| Robin D. Cook | Casting |
| Jillian Share | Executive Producer |
| Guillermo del Toro | Producer |
| Dusty Reeves | Art Department Coordinator |
| Shane Vieau | Set Decoration |
| Jeffrey A. Melvin | Set Decoration |
| Renee Fontana | Assistant Costume Designer |
| Cori Burchell | Costume Supervisor |
| Jonathan Oliveira | Casting Associate |
| Rocco Larizza | Special Effects Coordinator |
| Justin Turner | Casting Associate |
| Dennis Leonard | Supervising Sound Editor |
| Mac Smith | Sound Effects Editor |
| Albert Ribas | Sound Effects Editor |
| Dug Rotstein | Script Supervisor |
| Andre Zweers | Music Editor |
| Peter Afterman | Music Supervisor |
| Marc Bech | Sound Effects Editor |
| Katrina Schiller | Music Editor |
| Nick Colangelo | Visual Effects Coordinator |
| Leff Lefferts | Sound Effects Editor |
| David Slusser | Music Editor |
| Dennis Berardi | Visual Effects Supervisor |
| Stephanie Ingram | Hairstylist |
| Margaret Yen | Music Supervisor |
| Cliona Furey | Hair Department Head |
| Tom Starnes | Gaffer |
| Sylvie Bonniere | Seamstress |
| Randy Thom | Sound Designer |
| Scott Guitteau | Sound Effects Editor |
| Peter Dydo | Animation |
| Michael Innanen | Special Effects Supervisor |
| Jo Hughes | Visual Effects Producer |
| Paula Fleet | Key Hair Stylist |
| Robert Stecko | Camera Operator |
| Amy Wright | Choreographer |
| Paul Spaven | Rigging Gaffer |
| Martin Hesselink | Animation |
| Brandon Schaafsma | VFX Editor |
| Ronni Brown | Foley |
| Randy Thom | Supervising Sound Editor |
| Gilles Corbeil | Steadicam Operator |
| Robert Shoup | Sound Effects Editor |
| Mario Cacioppo | Makeup Artist |
| Jordan Samuel | Makeup Department Head |
| Cam McLauchlin | First Assistant Editor |
| Linda Dowds | Makeup Artist |
| Montse Ribé | Makeup Effects Designer |
| Oriol Tarragó | Sound Designer |
| Branko Racki | Stunt Coordinator |
| D.J. Carson | Unit Production Manager |
| Brandt Gordon | Supervising Art Director |
| Gilles Corbeil | Camera Operator |
| Callum Greene | Unit Production Manager |
| Elspeth Cassar | Production Coordinator |
| Brian Chumney | ADR Supervisor |
| Christopher Geggie | Property Master |
| Laird McMurray | Special Effects Coordinator |
| Jeff J.J. Authors | First Assistant Director |
| Penny Charter | Second Assistant Director |
| Kari Measham | Set Decoration Buyer |
| Joe Dzuban | Sound Re-Recording Mixer |
| Fred Kamping | Location Manager |
| Lora Hirschberg | Sound Re-Recording Mixer |
| Jim Likowski | Foley Editor |
| Angie Winstl | Set Decorating Coordinator |
| E. Larry Oatfield | Foley Editor |
| Bjorn Ole Schroeder | ADR Supervisor |
| Richard Quinn | ADR Supervisor |
| Kerry Hayes | Still Photographer |
| Marlene Rain | Set Decoration Buyer |
| Michael Semanick | Sound Re-Recording Mixer |
| John Ozolins | Transportation Coordinator |
| Krista Burbidge | Makeup Artist |
| Vincent Sullivan | Assistant Hairstylist |
| Nola Chaters | Costumer |
| Karen Eppstadt | Ager/Dyer |
| Erin Daprato | Set Costumer |
| Dave Greene | Title Designer |
| Colin Adams | Assistant Property Master |
| Kevin Lise | Assistant Property Master |
| Andrew Dininio | Carpenter |
| Cosmo Federico | Carpenter |
| Keith Hightower | Carpenter |
| Daniel Carrasco | Concept Artist |
| Oscar Chichoni | Concept Artist |
| Guy Davis | Concept Artist |
| David Meng | Concept Artist |
| Vicki Pui | Concept Artist |
| Keith Thompson | Concept Artist |
| John Mackenzie | Construction Coordinator |
| David Best | First Assistant Art Direction |
| Elis Y. Lam | First Assistant Art Direction |
| Sean Scoffield | First Assistant Art Direction |
| Colin Woods | First Assistant Art Direction |
| John Moran | Graphic Designer |
| Henry H. Gardner Jr. | Greensman |
| Chris Hanson | Painter |
| Bobby Quon | Painter |
| Jamie Staples | Painter |
| Danny Haeberlin | Researcher |
| Dave Axford | Sculptor |
| William Cheng | Set Designer |
| David G. Fremlin | Set Designer |
| Sonia Gemmiti | Set Designer |
| Alex Juzkiw | Set Designer |
| Michael Madden | Set Designer |
| Matt Middleton | Set Designer |
| Sorin Popescu | Set Designer |
| Andra Totirescu | Set Designer |
| Evan Webber | Set Designer |
| Aleksandra Marinkovich | Set Designer |
| Russell Moore | Set Designer |
| Chris Deeley | Set Dresser |
| Don McQueen | Set Dresser |
| John Morrison | Set Dresser |
| Keith Sly | Set Dresser |
| Toni Wong | Set Dresser |
| Alex Kutschera | Set Dresser |
| Jeff Poulis | Set Dresser |
| Adam Bocknek | Third Assistant Director |
| Missy Morris | Third Assistant Director |
| Phil Whitfield | Best Boy Electric |
| Jim Holmes | Best Boy Grip |
| Sandra Lombardi | Digital Imaging Technician |
| Ron Renzetti | Dolly Grip |
| Alistair Dempsey | Dolly Grip |
| Doug Black | Electrician |
| Sean Osadzuk | Electrician |
| Danny Piva | Electrician |
| Tom Taylor | Electrician |
| Ken Wiebe | Electrician |
| Mark Cyre | First Assistant "A" Camera |
| Joseph Micomonaco | First Assistant "B" Camera |
| Andrew Caney | Grip |
| Marc Purdy | Grip |
| Robert Rice | Grip |
| Joe Schroeder | Grip |
| Paul Sheridan | Grip |
| Robert Johnson | Key Grip |
| Jonathan Billings | Key Rigging Grip |
| Federico De Marco | Libra Head Technician |
| Alex Leung | Second Assistant "A" Camera |
| Alan G. Kelly | Second Assistant "B" Camera |
| John Stubbins | Techno Crane Operator |
| Mary Juric | Assistant Editor |
| Mike Paterson | Digital Intermediate |
| Chris Wallace | Digital Intermediate Colorist |
| Kevin Downer | Digital Intermediate Editor |
| Dave Muscat | Digital Intermediate Editor |
| Peter Armstrong | Digital Intermediate Producer |
| Brittany Farhat | Dailies Technician |
| Barbara Lucchesi | Dailies Technician |
| Candace Tempelmeyer | First Assistant Accountant |
| Sandra J. White | First Assistant Accountant |
| Andrew G. Munro | Payroll Accountant |
| David M. Rodriguez | Post Production Accountant |
| Sara Holmes | Post Production Accountant |
| Elaine Thurston | Production Accountant |
| Bryan Yaconelli | Production Executive |
| Lucia Haliburton | Production Secretary |
| Katharine Duke | Second Assistant Accountant |
| Kevin Michael Schembri | Second Assistant Accountant |
| Barbara Harris | ADR Voice Casting |
| Nick Butler | Casting Assistant |
| Ashley Gray | Casting Assistant |
| Zameret Kleiman | Background Casting Director |
| Lyle Cooley | Animation |
| Chris De Souza | Animation |
| Jason Edwardh | Animation |
| Tom Nagy | Animation |
| Somboun Souannhaphanh | Animation |
| Chris MacLean | CG Supervisor |
| Scott Riopelle | Compositing Supervisor |
| Tony Cybulski | Digital Compositor |
| Mark O. Hammond | Digital Compositor |
| Tetu Pawan | Digital Compositor |
| Kumar Umesh | Digital Compositor |
| Anna Joukova | Digital Compositor |
| Mike Borrett | Digital Effects Producer |
| Dominic Remane | Digital Effects Supervisor |
| Daniel Krzywania | Lead Animator |
| Ayo Burgess | VFX Lighting Artist |
| Lorne Kwechansky | VFX Lighting Artist |
| Elena Perreira | VFX Lighting Artist |
| Trey Harrell | VFX Lighting Artist |
| Jina Lee | Matte Painter |
| Mai-Ling Lee | Matte Painter |
| Jim Maxwell | Matte Painter |
| Andrew Nguyen | Matte Painter |
| Milan Schere | Matte Painter |
| Seema Schere | Matte Painter |
| Matt Schofield | Matte Painter |
| Min Kim | Rotoscoping Artist |
| Emma Liu | Rotoscoping Artist |
| Hao Meng | Rotoscoping Artist |
| Xizo Su | Rotoscoping Artist |
| Michael C. Tang | Rotoscoping Artist |
| Leo Bovell | VFX Artist |
| Chris Crozier | VFX Artist |
| Chris Johnson | VFX Artist |
| Abdul Mohamud | VFX Artist |
| Pearce Perkins | VFX Artist |
| Ronak Shah | VFX Artist |
| Cliff Bielawski | Visual Effects Coordinator |
| Natalie Broomhall | Visual Effects Coordinator |
| Becca Donohoe | Visual Effects Coordinator |
| Danni Henderson | Visual Effects Coordinator |
| Jenn Inkol | Visual Effects Coordinator |
| Alina Klinaeva | Visual Effects Coordinator |
| Karen McGregor | Visual Effects Coordinator |
| Mitch C. Duran | Special Effects Technician |
| Amber Skowronski | Special Effects Technician |
| Umberto Larizza | Special Effects Technician |
| Matthew Tulk | Special Effects Technician |
| Jennifer Mylrea | Stunts |
| David Murphy | Carpenter |
