 | Miles Robbins als Luke Nightingale |
 | Patrick Schwarzenegger als Daniel |
 | Sasha Lane als Cassie |
 | Hannah Marks als Sophie |
 | Mary Stuart Masterson als Claire |
 | Chase Sui Wonders als Makayla |
 | Katie Chang als Barista |
 | Chukwudi Iwuji als Dr. Cornelius Braun |
 | Jamar Greene als Campus Security Guard |
 | Cara Ronzetti als Joelle |
 | Michael Cuomo als James |
 | Andrew Bridges als Richard |
 | Madeleine Mfuru als Cop |
| Nathan Chandler Reid als Young Daniel |
| Daniel Marconi als John Thigpen |
| Rosanne Ma als Professor Abelard |
 | Lynn Marocola als FDNY Paramedic (uncredited) |
| Adam Egypt Mortimer | Director |
| Brian DeLeeuw | Novel |
| Brian DeLeeuw | Screenplay |
| Adam Egypt Mortimer | Screenplay |
| Daniel Noah | Producer |
| Josh C. Waller | Producer |
| Lisa Whalen | Producer |
| Elijah Wood | Producer |
| Peter Wong | Executive Producer |
| Alvaro R. Valente | Line Producer |
| Michael M. McGuire | Executive Producer |
| Elisa Lleras | Executive Producer |
| Emma Lee | Executive Producer |
| Stacy Jorgensen | Executive Producer |
| Johnny Chang | Executive Producer |
| Timur Bekbosunov | Executive Producer |
| Brett W. Bachman | Co-Executive Producer |
| Brett W. Bachman | Editor |
| Amber Horn | Casting |
| Danielle Aufiero | Casting |
| Kaet McAnneny | Production Design |
| Rosa Callejas | Art Direction |
| Roland Trafton | Set Decoration |
| Begonia Berges | Costume Design |
| Lyle Vincent | Director of Photography |
| Clark | Original Music Composer |
| Shelly Rodriguez | Set Decoration |
| Tywan Williams | Key Hair Stylist |
| Tyler J Tiffany | Stunt Double |
| Ben Rezendes | Stunt Double |
| James Newman | Stunt Double |
| Adam Lytle | Stunt Double |
| Luke Lesko | Stunt Coordinator |
| Califf Guzman | Stunts |
| Monique Ganderton | Fight Choreographer |
| Mark Fichera | Stunts |
| Jared Burke | Stunt Coordinator |
| George Loucas | Visual Effects Supervisor |
| Benjamin Mullin | Visual Effects Coordinator |
| Adrián Pierral | Digital Imaging Technician |
| Matt Russell | Visual Effects Producer |
| Thomas Hebert | Special Effects Makeup Artist |
| Tim Jarvis | Special Effects Makeup Artist |
| Neal Kennemore | Prosthetics Sculptor |
| Dalton Kutsch | Special Effects Makeup Artist |
| Michael J. O'Brien | Special Effects Makeup Artist |
| Mike Rotella | Prosthetics Sculptor |
| Miles Teves | Prosthetics Sculptor |
| Brian Van Dorn | Special Effects Technician |
| Rich Bussey | Foley Mixer |
| Cazz Cerkez | Foley Editor |
| Matt Davies | Foley Artist |
| Owen Granich-Young | Supervising Sound Editor |
| Austin Krier | Sound Effects Editor |
| Diana Sagristá | Sound Mixer |
| Jason Sharrow | ADR Mixer |
| Andy Welker | Supervising ADR Editor |
| Duccio Fabbri | First Assistant Director |
| Constance Pierce-Winters | Second Assistant Director |
| Joshua Pounds | Second Second Assistant Director |
| Martin Astles | Creature Design |
| Ben Bornstein | Prosthetic Makeup Artist |
| Douglas Brown | Special Effects Supervisor |
| Matt Rose | Prosthetics Sculptor |
| Devin Smith | Script Supervisor |
