 | Mark Ruffalo als Robert Bilott |
 | Anne Hathaway als Sarah Bilott |
 | Tim Robbins als Tom Terp |
 | Bill Pullman als Harry Dietzler |
 | Bill Camp als Wilbur Tennant |
 | Victor Garber als Phil Donnelly |
 | Mare Winningham als Darlene Kiger |
 | William Jackson Harper als James Ross |
 | Louisa Krause als Carla Pfeiffer |
 | Kevin Crowley als Larry Winter |
 | Bruce Cromer als Kim Burke |
 | Denise Dal Vera als Sandra Tennant |
| Richard Hagerman als Joe Kiger |
 | Abi Van Andel als Kathleen Welch |
 | John Newberg als Dr. Gillespie |
| Barry Mulholland als Charles Holliday |
 | Jeffrey Grover als Edward Wallace |
| Jim Azelvandre als Jim Tennant |
| Graham Caldwell als Teddy Bilott (3-5) |
| William 'Bucky' Bailey als Bucky Bailey |
 | Marcia Dangerfield als Grammer |
 | Brian Gallagher als David |
 | Michael Haney als Managing Partner |
| Barry G. Bernson als Retired Partner |
 | Michael King als Unpleasant Partner |
 | Greg Violand als Union Carbide Lawyer |
 | Michael Joseph Thomas Ward als DOW Lawyer |
| John Moll als Exxon Lawyer |
| Clara Harris als Receptionist |
 | Bella Falcone als Crystal Tennant (11-13) |
 | Scarlett Hicks als Amy Tennant |
 | Amy Morse als Tom's Secretary |
| Aidan Brogan als Teddy Bilott (12-14) |
| Nathan Slaughter als Teddy Bilott (7-10) |
| Beau Hartwig als Tony Bilott (10-11) |
| Jacob Bukowski als Tony Bilott (4) |
| Keating P. Sharp als Charlie Bilott (11-12) |
| Mikel Furlow als Silas Pfeiffer (5) |
 | Amy Warner als Sarah's Mother |
| Linnea Bond als Clerk |
| David Myers Gregory als Diner Owner |
| Shyra Thomas als Waitress |
| Ian Short als Doctor |
| Kyndra Jefferies als OB |
| Courtney DeCosky als All-American Mom |
| Ken Early als Chair of the Hearing |
 | Kelly Mengelkoch als Dr. Mary-Sue Kimball |
 | Annie Fitzpatrick als Judge |
| Buz Davis als Fire Captain |
| Ronald Jenkins als Security Guard |
 | Wynn Reichert als Mediator |
 | Mike Seely als Dr. Brooks |
 | Teri Clark als Neurologist |
| Brian Robertson als Minister |
 | Chaney Morrow als Young Farmer |
 | Jon Osbeck als Sarah's Brother |
 | Clyde Tyrone Harper als Judge #2 |
 | Lisa DeRoberts als Young Mother |
| Sara Mackie als Young Woman |
| Nathan Neorr als Local Reporter |
| Barbara Ann Crumm als Courtroom Deputy |
| Sheryl Annette Colley als Courtroom Employee |
| Logan Laskarzewski als Stenographer |
| Phil Fiorini als Pastor |
| Manuel Venegas Zepeda als Benihana Chef |
 | Jennie Malone als Guitar Player / Singer |
| Jason M. Griggs als Allied Lawyer |
| George Zamary als Awbury Lawyer |
| Kurt Roberson als Mover |
| Todd Minobe als Cow Puppeteer #1 |
| Jim Laprelle als Cow Puppeteer #2 |
 | Sydney Miles als Laura Doggett |
| Catch Farley als Scruffy Boy |
 | Trent Rowland als Tall Boy |
 | Geoff Falk als Worker #1 |
| Glen Yrigoyen als Worker #2 |
 | Elizabeth Marvel als Dr. Karen Frank (voice) |
| Ming Wang als Waitress (uncredited) |
 | Caleb Dwayne Tucker als Parkersburg Resident (uncredited) |
 | Lea Hutton Beasmore als EPA / Dinner Guest (uncredited) |
 | Anita Farmer Bergman als EPA Agent (uncredited) |
 | Lyman Chen als Hack Scientist (uncredited) |
| Tyler Craig als (uncredited) |
| David Fultz als Blood Test Patient (uncredited) |
| Robert Gerding als Lawyer (uncredited) |
| John W. Harden als Waiter (uncredited) |
| Al Harland als Parkersburg Citizen (uncredited) |
| Dennis Craig Hensley als DuPont Lawyer (uncredited) |
 | Daniel R. Hill als DuPont Security Guard (uncredited) |
| Marc Hockl als Church Goer (uncredited) |
| Sue Hopkins als Rob Bilott's Mother (uncredited) |
 | Matt Hudson als Police Officer (uncredited) |
| Conner P. Kelley als Smoker (uncredited) |
 | Angel Kerns als Parkersburg Resident (uncredited) |
 | Bret Aaron Knower als EPA (uncredited) |
| Rodger Masten als Hand Double (uncredited) |
| David Pittinger als Taft Lawyer (uncredited) |
 | Joanne Popolin als EPA Lawyer / Taft Lawyer (uncredited) |
 | Ramona Schwalbach als Plantiff's Family (uncredited) |
 | Carly Tamborski als EPA Hearing Attendee / Church Parishioner (uncredited) |
 | Jenny McManus als Protester / Church Attendee / Blood Donor (uncredited) |
 | Derek Polen als Taft Lawyer (uncredited) |
 | John E. Brownlee als Taft Lawyer (uncredited) |
| Todd Haynes | Director |
| Mario Correa | Writer |
| Mark Ruffalo | Producer |
| Jonathan King | Executive Producer |
| Pamela Koffler | Producer |
| Jeff Skoll | Producer |
| Michael Sledd | Executive Producer |
| Christine Vachon | Producer |
| Hannah Beachler | Production Design |
| Jesse Rosenthal | Art Direction |
| Helen Britten | Set Decoration |
| Affonso Gonçalves | Editor |
| Drew Kunin | Sound Mixer |
| Miles Michael | Art Direction |
| Edward Lachman | Director of Photography |
| Matthew Michael Carnahan | Writer |
| Timothy Bird | Co-Producer |
| Parry Creedon | Unit Production Manager |
| Timothy Bird | First Assistant Director |
| Alison C. Rosa | Second Assistant Director |
| Curtis Smith | First Assistant Director |
| Craig Haagensen | Second Unit Director |
| Blair Howley | Second Second Assistant Director |
| Justin Ayers | Art Department Manager |
| Bob Riggs | Special Effects Supervisor |
| Chad Ball | Special Effects Technician |
| Marcelo Zarvos | Original Music Composer |
| Nathaniel Rich | Writer |
| Robert Kessel | Executive Producer |
| Christopher Peterson | Costume Design |
| Sarah Young | Assistant Art Director |
| Laura Rosenthal | Casting |
| Randall Poster | Music Supervisor |
| Tom Dziak | Stunt Double |
| Richard Fike | Stunt Coordinator |
| Danny Brown | Assistant Art Director |
| Cierra Madison | Set Designer |
| Natalie LeCompte | Graphic Designer |
| Debbie Stratis | Art Department Coordinator |
| Mark Woods | Leadman |
| Sarah Young | Assistant Set Decoration |
| Kay Wolfley | Set Decorating Coordinator |
| Jason Beveridge | Set Dresser |
| Kirsten Lee Houck | Set Dresser |
| Mike Reuter | Set Dresser |
| David Schellenberger | Set Dresser |
| Ryan Tudor | Set Dresser |
| Vinny Mazzarella | Property Master |
| Joe Coppola | Assistant Property Master |
| Chris Haarhoff | "A" Camera Operator |
| Chris Haarhoff | Steadicam Operator |
| Oliver Cary | "B" Camera Operator |
| Eric Swanek | First Assistant "A" Camera |
| Richard S. Crumrine Jr. | First Assistant "B" Camera |
| Joe Bou | Second Assistant "A" Camera |
| Colleen Mleziva | Second Assistant "B" Camera |
| Maninder K. Saini | Digital Imaging Technician |
| Eric Ransbottom | Camera Loader |
| Drew Kunin | Production Sound Mixer |
| Mark Goodermote | Boom Operator |
| Zach Mueller | Utility Sound |
| John W. DeBlau | Gaffer |
| Russ Faust | Best Boy Electric |
| Jake Heim | Electrician |
| Kevin Hines | Electrician |
| Donnie Schneider | Electrician |
| Clifton Radford | Generator Operator |
| Scott Lipez | Rigging Gaffer |
| Chance Madison | Rigging Grip |
| Mitchell Andrew Lillian | Key Grip |
| Paul Candrilli | Best Boy Grip |
| Brendan Lowry | Dolly Grip |
| Mike Dittiacur | Dolly Grip |
| Tori Roloson | Grip |
| Patrick James Ryan | Grip |
| Michael Salamone | Grip |
| Zachary Cahill | Grip |
| Dan Jarrell | Key Rigging Grip |
| Jeff Fisher | Rigging Grip |
| Matthew Legner | Rigging Grip |
| John Zanardelli | Rigging Grip |
| Katie Riggs | Special Effects Coordinator |
| Chad Ball | Pyrotechnician |
| Caroline Quiroga | Assistant Costume Designer |
| Katie Saunders | Costume Supervisor |
| Zachary Sheets | Key Costumer |
| Jessica Arthur | Costumer |
| Chelsea Ostrow | Costumer |
| Robin Fields | Costumer |
| Joy Galbraith | Costumer |
| Greta Stokes | Costumer |
| Ashley Wilz | Costumer |
| Ashley Marie Parker | Costumer |
| Patricia Regan | Makeup Department Head |
| Jodi Byrne | Key Makeup Artist |
| Michael Marino | Prosthetic Designer |
| Dan Gilbert | Prosthetic Makeup Artist |
| Crystal Jurado | Prosthetic Makeup Artist |
| David T. Woodruff | Prosthetic Makeup Artist |
| Marie Larkin | Hair Department Head |
| Anna Maria Reyer | Key Hair Stylist |
| Anne Morgan | Makeup Artist |
| Crystal Lewis | Hairstylist |
| Joaquin Diego Prange | Location Manager |
| Rehya Young | Location Manager |
| Jane Streeter | Assistant Location Manager |
| Audra Duval | Assistant Location Manager |
| Ali A. Rashti | Assistant Location Manager |
| Nicholas Moore | Assistant Location Manager |
| Evan C. Eley | Location Coordinator |
| Jacob Berry | Location Assistant |
| Max Fogle | Location Assistant |
| Cynthia Garcia Walker | Production Accountant |
| Sam Patton | First Assistant Accountant |
| Tony Cypres | Assistant Accountant |
| Michelle Dobrozsi | Assistant Accountant |
| Mara Patton | Assistant Accountant |
| Rachel Schneider | Post Production Accountant |
| Caroline Stevens-Sommers | Production Coordinator |
| Pauline S. Storms | Assistant Production Coordinator |
| Asia Farmer | Production Secretary |
| Belle Francisco | Script Supervisor |
| Kim Ostroy | Casting Associate |
| D. Lynn Meyers | Location Casting |
| Maggie Cramer | Extras Casting Assistant |
| Maya Farhat | Extras Casting Assistant |
| Guy Adan | Unit Publicist |
| Mary Cybulski | Still Photographer |
| Elizabeth Himelstein | Dialect Coach |
| Patricia Heim | Studio Teacher |
| Paul Peabody | Construction Coordinator |
| Kenneth Miles | Greensman |
| Frank Conforti | Transportation Coordinator |
| Craig Metzger | Transportation Captain |
| John Pishko | Transportation Captain |
| Jeff Montgomery | Transportation Co-Captain |
| Pamela Ford | Craft Service |
| Isabel Henderson | Post Production Supervisor |
| Perri Pivovar | First Assistant Editor |
| Jaime Sukonnik | Assistant Editor |
| Anne O'Brien | Assistant Editor |
| Leslie Shatz | Sound Re-Recording Mixer |
| Leslie Shatz | Sound Designer |
| Eliza Paley | ADR Supervisor |
| Luciano Vignola | Dialogue Editor |
| Jon Flores | Sound Effects Editor |
| Daniel Ward | Foley Editor |
| Ryan Collison | Foley Mixer |
| Nick Seaman | Foley Mixer |
| Bobby Johanson | ADR Mixer |
| Tom Kramer | Music Editor |
| Mark Baechle | Orchestrator |
| Randy Miller | Orchestrator |
| Jan Chalupecký | Conductor |
| Milena Erke | Music Coordinator |
| Chris Haney | Visual Effects Supervisor |
| Jeffrey Lazar | Second Unit First Assistant Director |
| Marlene McCarty | Title Designer |
