 | Ethan Hawke als Edward Dalton |
 | Sam Neill als Charles Bromley |
 | Willem Dafoe als Lionel 'Elvis' Cormac |
 | Claudia Karvan als Audrey Bennett |
 | Isabel Lucas als Alison Bromley |
 | Vince Colosimo als Christopher Caruso |
 | Jay Laga'aia als Senator Turner |
 | Michael Dorman als Frankie Dalton |
 | Harriet Minto-Day als Lisa Barrett |
 | Tiffany Lamb als News Reader |
 | Mungo McKay als Colin Briggs |
 | Emma Randall als Ellie Landon |
 | Charlotte Wilson als Joy Watkins |
 | Christopher Kirby als Jarvis Bayom |
 | Troy MacKinder als Officer Hobbs |
 | Robyn Moore als Forensic Investigator Simms |
 | Damien Garvey als Senator Westlake |
 | Paul Sonkkila als General Williams |
 | Ben Siemer als Police Officer |
 | Renai Caruso als Coffee Shop Attendant |
 | Amanda Buchanan als Nurse |
 | Joel Spreadborough als Vampire Subject |
 | Candice Storey als Onlooker |
| Sahaj Dumpleton als Homeless Vampire |
| Gabriella Di Labio als Businesswoman |
| Kirsten Cameron als Subway Commuter |
 | Lisa Cunningham als Nurse |
| Michelle Atkinson als Mother |
| Anne Bennetts als Onlooker |
| Kellie Vella als Subsider in Garage |
| Victoria Williams als Vampire School Kid |
| Zoe White als Vampire School Kid |
| Aolani Roy als Vampire School Kid |
| Callum McLean als Vampire School Kid |
| Jarrad Pon als Vampire School Kid |
| Kevin Zwierzchaczewski als Lab Technician |
 | David Vallon als Janitor |
 | Brooke Chamberlain als Isobel (uncredited) |
| Alex Revan als Rygar (uncredited) |
 | Todd Levi als Commissioner Turnbull |
| Peter Block | Executive Producer |
| Peter Spierig | Screenplay |
| Christopher Gordon | Original Music Composer |
| Jason Constantine | Executive Producer |
| George Liddle | Production Design |
| Michael Spierig | Director |
| Nikki Barrett | Casting |
| Peter Spierig | Director |
| Matt Villa | Editor |
| Bryan Furst | Producer |
| Michael Spierig | Screenplay |
| Sean Furst | Producer |
| Stuart Wood | Line Producer |
| Ben Nott | Director of Photography |
| Todd Fellman | Producer |
| Tricia McInally | Art Department Coordinator |
| Chad Malbon | Visual Effects Producer |
| Tony Clarke | Location Manager |
| George Liddle | Costume Design |
| Troy MacKinder | Dialect Coach |
| Nick Breslin | Sound Designer |
| Wayne Pashley | Sound Designer |
| Matthew Putland | Set Decoration |
| Klaus Kastberg | Set Designer |
| Rangi Sutton | Visual Effects Supervisor |
| Paula Whiteway | Set Designer |
| Phil Heywood | Sound Re-Recording Mixer |
| Jacinta Leong | Set Designer |
| Wayne Pashley | Supervising Sound Editor |
| Jackie Sullivan | Script Supervisor |
| Bill Booth | Art Direction |
| Jason Ewart | Steadicam Operator |
| Ben Rothstein | Still Photographer |
| Kym Sainsbury | Makeup Department Head |
| Damian Candusso | Sound Designer |
| Steve Unwin | Still Photographer |
| Greg Gilbert | Camera Operator |
| Richard Taylor | Makeup Effects |
| Ricky Schamburg | Additional Camera |
| Chris Anderson | Stunt Coordinator |
| Jason Waide | Rigging Gaffer |
| Steven Boyle | Makeup Effects |
| Frances Richardson | Makeup Effects |
| Samantha Lyttle | Makeup Effects |
| Mick O'Brien | Gaffer |
| Matthew Ozerski | Visual Effects Editor |
| Basia Plachecki | Production Manager |
| Sophie Siomos | Production Accountant |
| Ben Parkinson | Casting |
| Chris Brown | Producer |
| Lenny Holmdahl | Property Master |
| Libby Villa | Dialogue Editor |
| Derryn Pasquill | Dialogue Editor |
| Jenny T. Ward | Dialogue Editor |
| Vivienne Boo Fox | Additional Hairstylist |
| Cristina Patterson | Contact Lens Painter |
| Carla Vicenzino | Makeup & Hair |
| Kym Sainsbury | Hair Department Head |
| Troy Follington | Makeup & Hair |
| Simon Joseph | Makeup & Hair |
| Tess Natoli | Makeup & Hair |
| Samantha Lyttle | Special Effects Key Makeup Artist |
| Samantha Lyttle | Makeup Artist |
| Darin Rose | Makeup Artist |
| Karen Kelly | Wig Designer |
| Toby Barron | Prosthetics |
| Adam Head | Prosthetics |
| Vince Holland | Prosthetics |
| Antony McMullen | Prosthetics |
| Jamie Beswarick | Prosthetics Sculptor |
| Don Brooker | Prosthetics Sculptor |
| Bill Hunt | Prosthetics Sculptor |
| Gary Hunt | Prosthetics Sculptor |
| Jamie Leslie | First Assistant Director |
| Nick McKinnon | Second Assistant Director |
| Brett Popplewell | Second Unit First Assistant Director |
| Rachael O'Brien | Second Assistant Director |
| Ian 'Thistle' Thorburn | Second Unit Director |
| Sarah Jane Walsh | Third Assistant Director |
| Stephanie Amantea | Wardrobe Assistant |
| Martin Heusel | Wardrobe Coordinator |
| Bud Hopes | Extras Casting |
| Ben Parkinson | Extras Casting |
| Ian 'Thistle' Thorburn | Second Unit Director of Photography |
| Martin Oswin | ADR Mixer |
| Rich Macar | ADR Recordist |
| Bruce Emery | Dolby Consultant |
| John Simpson | Foley Artist |
| Jason Hancock | Foley Recordist |
| Dan McMahon | Sound Assistant |
| Craig Walmsley | Sound Recordist |
| Sonal Joshi | Supervising Dialogue Editor |
| Chris Healy | Additional First Assistant Camera |
| Peter Critchley | Assistant Electrician |
| Darryl Dempsey | Assistant Electrician |
| Nathan Walton | Assistant Electrician |
| Stephen Head | Best Boy Electric |
| Michael Rich | Dolly Grip |
| Trent Williamson | Dolly Grip |
| Luke Nixon | First Assistant Camera |
| Daniel Clark | Focus Puller |
| Marcus Ballantine | Grip |
| Billy Harmer | Grip |
| Damien King | Grip |
| Michael Carl Smith | Grip |
| Ivan Valjan | Grip |
| Grant Nielsen | Key Grip |
| Mark Bills | Lighting Technician |
| Scott Hamilton | Lighting Technician |
| Tim Buckland | Lighting Technician |
| Steven Magrath | Second Assistant "A" Camera |
| Matthew Floyd | Second Assistant "B" Camera |
| Tristan Davies | Second Assistant Camera |
| Polly Pierce | Video Assist Operator |
| Peter Spierig | 3D Animator |
| Mick Harkin | Compositor |
| Naomi Anderlini | Compositor |
| David Edwards | Compositor |
| Daniel Loui | Compositor |
| Tahl Niran | Compositor |
| Randy Vellacott | Compositor |
| Alicia Aguilera | Digital Compositor |
| Loren Robinson | Digital Compositor |
| Demis Lyall-Wilson | Digital Compositor |
| D.J. Nicke | Lead Animator |
| Jonathan Taranto | Matte Painter |
| Blake Muir | Rotoscoping Artist |
| Max Robinson | Rotoscoping Artist |
| Andrew Smith | Rotoscoping Artist |
| James Rogers | Senior Visual Effects Supervisor |
| Daniel Mons | Systems Administrators & Support |
| Kirsty Martin | Visual Effects Coordinator |
| Daniel Phillis | Animation |
| Clint Ingram | Special Effects Supervisor |
| Andrew Goodall | Special Effects Technician |
| Murray Philip | Special Effects Technician |
| Greg Tuckwell | Special Effects Technician |
| Jeremy Piggott | Special Effects Technician |
| Phill Rylance | Special Effects Technician |
| Steve Rungwerth | Special Effects Technician |
| Simon Gill | Assistant Set Dresser |
| Gillian Butler | Set Dresser |
| Luke Hughes | Carpenter |
| Rick Jarvis | Carpenter |
| Innes Stenhouse | Carpenter |
| Phil Shearer | Conceptual Design |
| Noel McCartney | Construction Foreman |
| Andrew Gardiner | Construction Manager |
| George Kabot | Graphic Designer |
| Johann Kwiatkowski | Graphic Designer |
| Adam Mawby | Greensman |
| Ben Fraser | Painter |
| Gary Cameron | Propmaker |
| Daniel Cairns | Props |
| Jodie Whetter | Set Buyer |
| Jodie Whetter | Set Dresser |
| Phoebe McMahon | Assistant Set Decoration |
| Wayne Diskin | Standby Carpenter |
| Carlin Bull | Standby Painter |
| Graeme Callander | Storyboard Artist |
| Richard Francis-Bruce | Additional Editor |
| Justin McDonald | Colorist |
| John Lee | Digital Intermediate |
| Justin Tran | Digital Intermediate |
| Adrian Hauser | Digital Intermediate Colorist |
| Heather Galvin | Online Editor |
| Naomi Anderlini | Title Designer |
| Jeff Gribble | Armorer |
| Rita Siomos | First Assistant Accountant |
| Alex Fewster | Production Secretary |
| Stuart Monksfield | Project Manager |
| Rebecca Howcroft | Assistant Accountant |
| Angela Barac | Assistant Production Coordinator |
| Steven Boyle | Makeup Effects Designer |
| Steven Boyle | Creature Design |
| Sheila Lind | Production Coordinator |
| Troy MacKinder | Dialogue Coach |
| Eugene Intas | Art Direction |
