 | Sam Rockwell als Wolf (voice) |
 | Marc Maron als Snake (voice) |
 | Awkwafina als Tarantula (voice) |
 | Craig Robinson als Shark (voice) |
 | Anthony Ramos als Piranha (voice) |
 | Richard Ayoade als Professor Marmalade (voice) |
 | Zazie Beetz als Diane Foxington (voice) |
 | Alex Borstein als Police Chief Misty Luggins (voice) |
 | Lilly Singh als Tiffany Fluffit (voice) |
 | Barbara Goodson als Old Lady (voice) |
 | Dina Morrone als Museum Announcer / Diane's A.I. Assistant (voice) |
 | Michael Godere als Delivery Driver / Museum Guest 1 (voice) |
 | Kelly Cooney Cilella als Prison Guard 1 / Gala Guest 1 (voice) |
 | Walt Dohrn als Scientist / Gala Guest 3 (voice) |
 | David P. Smith als Prison Guard 2 / Gala Guest 2 / Protestor (voice) |
| John Venzon als Museum Guest 2 / Panicked Cop (voice) |
| Jesse Averna als Prison Guard 3 (voice) |
| Rebecca Huntley | Producer |
| Etan Cohen | Executive Producer |
| Damon Ross | Producer |
| Lisa Curtis Saunders | Pipeline Technical Director |
| Aaron Blabey | Executive Producer |
| Pierre Perifel | Director |
| Daniel Pemberton | Original Music Composer |
| Matt Baer | Visual Effects Supervisor |
| John Venzon | Editor |
| Julian Slater | Supervising Sound Editor |
| Julian Slater | Sound Re-Recording Mixer |
| Michael Babcock | Sound Re-Recording Mixer |
| Brandon Jones | Sound Designer |
| Jason W. Jennings | Sound Designer |
| Floriane Marchix | Art Direction |
| Luc Desmarchelier | Production Design |
| Etan Cohen | Screenplay |
| Hilary Winston | Co-Writer |
| Yoni Brenner | Co-Writer |
| Nelson Yokota | Head of Story |
| Todd Jansen | Head of Layout |
| Christi Soper Hilt | Casting |
| Patrick Hughes | Producer |
| Liang-Yuan Wang | Lighting Supervisor |
| Jorge A. Capote | Lead Animator |
| Min Hong | Lead Animator |
| Drew Adams | Animation |
| Luiza Alaniz | Animation |
| David Badgerow | Animation |
| Ludovic Bouancheau | Animation |
| Guillermo Careaga | Animation |
| Prashanth Cavale | Animation |
| Joseph Chong | Animation |
| Albert Rubio | Animation |
| Elisabeth Franklin | Animation |
| David Couchariere | Animation |
| Michelle Cowart | Animation |
| Ares Deveaux | Animation |
| Patrick Giusiano | Animation |
| Ravi Kamble Govind | Animation |
| Andrew Harkins | Animation |
| Brendan Kirschbaum | Animation |
| Lindsey Butterworth Langston | Animation |
| Eric Lees | Animation |
| David Lisbe | Animation |
| Fredrik Nilsson | Animation |
| Garrett O'Neal | Animation |
| Tyler Phillips | Animation |
| David Polk | Animation |
| Reece Porter | Animation |
| Marco Regina | Animation |
| Jeremy Schaefer | Animation |
| Alex Ferreira Simões | Animation |
| Alexander Snow | Animation |
| Emily Springer | Animation |
| Manar Al Tawam | Animation |
| Kelly Vawter | Animation |
| Ryan Vicik | Animation |
| Dan Wagner | Animation |
| Jeff Williams | Animation |
| John Wong | Animation |
| Taylor Krahenbuhl | Character Designer |
| Julien Le Rolland | Character Designer |
| Jorge A. Capote | Character Designer |
| Anthony Holden | Character Designer |
| Jeremy Bernstein | Storyboard Artist |
| Hanna Kim | Storyboard Artist |
| Mike Surrey | Storyboard Artist |
| Katherine de Vries | Storyboard Artist |
| Marco Regina | Storyboard Artist |
| Young Ki Yoon | Storyboard Artist |
| Adam Rosette | Storyboard Artist |
| Alice Herring | Storyboard Artist |
| Leo Matsuda | Storyboard Artist |
| Claire Morrissey | Storyboard Artist |
| John Puglisi | Storyboard Artist |
| Michael Lester | Storyboard Artist |
| Susan Misner | Choreographer |
| Jesse Averna | Additional Editor |
| Tom Scott | Assistant Editor |
| Stephen Castro | Assistant Editor |
| Laura Minto | First Assistant Editor |
| Christine Lojko Haslett | Associate Editor |
| Katherine Ramos | Production Supervisor |
| Katie Greathouse | Music Editor |
| Sam Okell | Score Engineer |
| Sam Okell | Mixing Engineer |
| Andy Maxwell | Sound Recordist |
| Andrew Skeet | Conductor |
| Andrew Skeet | Orchestrator |
| Chadd Ferron | Animation |
| Yung Pham | Animation |
| Robyne Powell | Animation |
| John Hill | Animation Supervisor |
| Antony Gray | Animation Supervisor |
| Willy Harber | Animation Supervisor |
| Rani Naamani | Animation Supervisor |
| Liron Topaz | Animation Supervisor |
| Benjamin Willis | Animation Supervisor |
| Onur Yeldan | Animation Supervisor |
| Tracy Larson | Production Manager |
| Michael Lynn | Production Manager |
| JP Sans | Head of Animation |
| Chelsea Blecha | Visual Development |
| Tom MacDougall | Visual Development |
| Leo Sanchez Barbosa | Visual Development |
| Rémi Salmon | Visual Development |
| Angela Sung | Visual Development |
| Peter Maynez | Visual Development |
| Camilo Castro | Visual Development |
| Guillaume Fesquet | Visual Development |
| Aurora Jimenez Seoane | Visual Development |
| Ritchie Sacilioc | Visual Development |
| Luca Pisanu | Visual Development |
| Vahe Yefremian | Visual Development |
| Maurissa Horwitz | Additional Editor |
| James D. Bissell | Thanks |
| John K. Carr | Thanks |
| Shayna Cohen | Thanks |
| Nick Fletcher | Thanks |
| Jillian Gomez | Thanks |
| Sam Hinton | Thanks |
| Janine Jones-Clark | Thanks |
| Elise Konialian | Thanks |
| David Kwong | Thanks |
| Emerlynn Lampitoc | Thanks |
| James Ryan | Thanks |
| Jerry Schmitz | Thanks |
| Aaron Blabey | Novel |
