 | Martin Freeman als Pirate with a Scarf (voice) |
 | Hugh Grant als Pirate Captain (voice) |
 | Imelda Staunton als Queen Victoria (voice) |
 | David Tennant als Charles Darwin (voice) |
 | Jeremy Piven als Black Bellamy (voice) |
 | Salma Hayek Pinault als Cutlass Liz (voice) |
 | Lenny Henry als Peg Leg Hastings (voice) |
 | Brian Blessed als Pirate King (voice) |
 | Brendan Gleeson als Pirate with Gout (voice) |
 | Ashley Jensen als Surprisingly Curvaceous Pirate (voice) |
 | Ben Whitehead als Pirate Who Likes Sunsets and Kittens (voice) |
 | Russell Tovey als Albino Pirate (voice) |
 | David Schneider als Scarlett Morgan (voice) |
 | Mike Cooper als Admiral Collingwood (voice) |
| Tom Doggart als Additional Voices (voice) |
| Sophie Jerrold als Additional Voices (voice) |
| Sophie Laughton als Additional Voices (voice) |
 | Peter Lord als Additional Voices (voice) |
 | Kayvan Novak als Additional Voices (voice) |
 | David Schaal als Additional Voices (voice) |
 | Mitchell Mullen als Gameshow Host (voice) (uncredited) |
 | Anton Yelchin als Albino Pirate (US) (voice) |
 | Mario Joyner als Pirate Who Likes Sunsets and Kittens (US) (voice) |
| Peter Lord | Director |
| Gideon Defoe | Writer |
| Carla Shelley | Executive Producer |
| Ludovic Berardo | Animation |
| Ashley Boddy | Storyboard |
| Paul Bolger | Storyboard |
| Darren Burgess | Animation |
| Dug Calder | Animation |
| Jason Comley | Animation |
| Jonny Duddle | Art Department Manager |
| Alison Evans | Animation |
| Jo Fenton | Animation |
| Jay Grace | Animation Supervisor |
| Carlos Grangel | Art Department Manager |
| Wendy Griffiths | Animation |
| Richard Haynes | Animation |
| Todor Iliev | Animation |
| Andy Janes | Storyboard |
| Malcolm Lamont | Animation |
| Christophe Lourdelet | Art Department Manager |
| Gareth Love | Animation |
| Rhodri Lovett | Animation |
| Jan-Erik Maas | Animation |
| Grant Maisey | Animation |
| Andree Neemann | Animation |
| Kris Pearn | Storyboard |
| Julia Peguet | Animation |
| Christopher Peladan | Animation |
| Pascual Perez | Animation |
| Florian Perinelle | Animation |
| Loyd Price | Animation Supervisor |
| Dan Ramsay | Animation |
| Claire Rolls | Animation |
| Michael Salter | Art Department Manager |
| Rita Sampaio | Animation |
| Michael Schlingmann | Animation |
| Tom Sewell | Animation |
| Laurie Sitzia | Animation |
| Sharon Smith | Storyboard |
| Andy Spilsted | Animation |
| Robert Stevenhagen | Storyboard |
| Andy Symanowski | Animation |
| Philippe Tardif | Animation |
| Darren Thomson | Animation |
| Jean-Paul Vermeulen | Storyboard |
| Jean-Philippe Vine | Storyboard |
| David Vinicombe | Storyboard |
| Justine Waldie | Animation |
| Dean Watson | Animation |
| Ian Whitlock | Animation |
| Lee Wilton | Animation |
| Matt Jones | Storyboard Artist |
| Beth MacDonald | Assistant Camera |
| Arthur Sheriff | Unit Publicist |
| Chris Johnson | Assistant Camera |
| Mike Smith | Storyboard |
| Jeff Newitt | Co-Director |
| Gary Kachelhoffer | Animation |
| Jay Clarke | Storyboard |
| Peter Lord | Producer |
| Julie Lockhart | Producer |
| David Sproxton | Producer |
| Sarah Smith | Co-Executive Producer |
| Susan Breen | Associate Producer |
| Theodore Shapiro | Original Music Composer |
| Steve Cox | Animation |
