 | Antonio Banderas als El Mariachi |
 | Salma Hayek Pinault als Carolina |
 | Joaquim de Almeida als Bucho |
 | Steve Buscemi als Buscemi |
 | Cheech Marin als Short Bartender |
 | Carlos Gómez als Right Hand |
 | Quentin Tarantino als Pick-Up Guy |
 | Tito Larriva als Tavo |
 | Angel Aviles als Zamira |
 | Danny Trejo als Navajas |
 | Abraham Verduzco als Niño |
 | Carlos Gallardo als Campa |
| Albert Michel Jr. als Quino |
 | David Alvarado als Buddy |
 | Angela Lanza als Tourist Girl |
 | Mike Moroff als Shrug |
 | Robert Arevalo als Opponent |
| Gerardo Moscoso als Priest |
 | Peter Marquardt als Moco |
 | Consuelo Gómez als Domino |
 | Jaime de Hoyos als Bigoton |
 | Cristos als Cristos |
 | Richie Gaona als Case Opener |
| Tommy Nix als Fighting Barfly |
| Patricia Vonne als Bar Girl |
 | Elizabeth Rodriguez als Mariachi Fan |
 | Mark Dalton als Fighting Barfly |
 | Reinol Martinez als Guy Scolding Niño Outside Tarasco Bar (uncredited) |
| Diego Sandoval als Empty Gun Man (uncredited) |
| Robert Rodriguez | Director |
| Robert Rodriguez | Producer |
| Cecilia Montiel | Production Design |
| Carlos Gallardo | Co-Producer |
| Robert Rodriguez | Editor |
| Guillermo Navarro | Director of Photography |
| Graciela Mazón | Costume Design |
| Robin Anderson | Script Supervisor |
| Rico Torres | Still Photographer |
| Dean Beville | Supervising Sound Editor |
| Steve M. Davison | Stunt Coordinator |
| Bob Shelley | Special Effects Coordinator |
| Mark Ulano | Production Sound Mixer |
| B. Tennyson Sebastian III | Sound Re-Recording Mixer |
| Sergio Reyes | Sound Re-Recording Mixer |
| Bill Borden | Producer |
| Elizabeth Avellan | Co-Producer |
| Reuben Cannon | Casting |
| Tony Mark | Unit Production Manager |
| Luz María Rojas | Unit Production Manager |
| Batan Silva | First Assistant Director |
| Diego Sandoval | Second Assistant Director |
| Karyn Rachtman | Music Supervisor |
| Felipe Fernández del Paso | Art Direction |
| David Alvarado | Stunts |
| Henry Kingi Jr. | Stunts |
| Troy Robinson | Stunts |
| Richie Gaona | Stunts |
| Julian Bucio | Stunts |
| Javier Lambert | Stunts |
| Gilbert Rosales | Stunts |
| Allan R.J. Joseph | Stunts |
| Ricardo M. Kaplan | Assistant Art Director |
| Robert Rodriguez | Steadicam Operator |
| Fernando Moreno | Chief Lighting Technician |
| Jesús Romero | Key Grip |
| Joaquin Silva | Second Second Assistant Director |
| Cheri Hall | Production Accountant |
| Elsa Hermoso | Production Accountant |
| Mariano Carranco | Location Manager |
| Terry Haskell | Property Master |
| Mark Green | Assistant Property Master |
| Michael Connell | Music Editor |
| Greg Hedgepath | Sound Editor |
| Gary S. Gerlich | Sound Editor |
| Matthew C. Beville | Sound Editor |
| Pedro Mejía | Boom Operator |
| Judee Flick | ADR Editor |
| Frank Smathers | Foley Editor |
| Charles Ewing Smith | Dialogue Editor |
| Tamara Smith | Post Production Supervisor |
| Don Levy | Unit Publicist |
| David Orr | Color Timer |
| Gloria Kaiser | Color Timer |
| Donah Bassett | Negative Cutter |
| Robert Rodriguez | Writer |
| David Hidalgo | Original Music Composer |
| Louie Pérez | Original Music Composer |
| Cesar Rosas | Original Music Composer |
| Conrad Lozano | Original Music Composer |
| Steve Berlin | Original Music Composer |
| Rosie Duprat Fort | Assistant Hairstylist |
| Rosie Duprat Fort | Assistant Makeup Artist |
| Ermahn Ospina | Hairstylist |
| Ermahn Ospina | Makeup Artist |
| Douglas J. White | Special Effects Makeup Artist |
| Douglas J. White | Prosthetics |
| Allan A. Apone | Makeup Designer |
| Steve M. Davison | Second Unit Director |
| Antonio Banderas | Special Guest Director |
| Ernesto López Ríos | Construction Coordinator |
| Eduardo Lopez | Lead Set Dresser |
| Edmond J. Coblentz Jr. | Assistant Sound Editor |
| Thomas Raymond Fabbricante | Assistant Sound Editor |
| Tim Gomillion | Sound Recordist |
| Larry Hopkins | Sound Mixer |
| Derek Marcil | ADR Mixer |
| Marvin Walowitz | Sound Effects Editor |
| B.J. Shelley | Special Effects Assistant |
| Malinda Shelley | Special Effects Assistant |
| Steve Fink | Prosthetics |
| Ramiro González | Stunts |
| Robert Arevalo | Stunts |
| David Berryman | Second Assistant Camera |
| Ricardo Oscar Fernández | First Assistant Camera |
| Joaquin Gutierrez | Second Assistant Camera |
| Gerardo Manjarrez | First Assistant Camera |
| Marco Morales Echeverría | Grip |
| Antonio Sánchez Romero | Best Boy Electric |
| Douglas Kirkland | Still Photographer |
| Juan Martín | Electrician |
| David Giella | Casting Assistant |
| Alana Caudillo | Wardrobe Assistant |
| Ireri Mazón Salas | Wardrobe Assistant |
| Carlos Mungia Rodríguez | Wardrobe Supervisor |
| Adolfo Ramírez | Wardrobe Supervisor |
| Erik C. Andersen | Associate Editor |
| Daniel Fort | Assistant Editor |
| Ethan Maniquis | Assistant Editor |
| Joaquin Gonzalo Avellán | Assistant Editor |
| Darren Block | Post Production Assistant |
| Joaquin Gonzalo Avellán | Assistant Location Manager |
| Nick Glennie-Smith | Musician |
| Tito Larriva | Additional Music |
| Steven Hufsteter | Musician |
| Mark Gantt | Driver |
| Kenny Mason | Transportation Coordinator |
| Fernanda Echeverria | Production Coordinator |
| Pamela Jaeckle | Production Coordinator |
| Barry Rosenbush | Production Assistant |
| Daniel J. Shaw | Production Assistant |
| Kelly Frazier | Assistant Production Coordinator |
