 | Meryl Streep als Florence Foster Jenkins |
 | Hugh Grant als St. Clair Bayfield |
 | Simon Helberg als Cosmé McMoon |
 | Rebecca Ferguson als Kathleen Weatherley |
 | Nina Arianda als Agnes Stark |
 | Stanley Townsend als Phineas Stark |
 | Allan Corduner als John Totten |
 | Christian McKay als Earl Wilson |
 | David Haig als Carlo Edwards |
 | John Sessions als Dr. Hermann |
 | Brid Brennan als Kitty |
 | John Kavanagh als Arturo Toscanini |
 | Pat Starr als Mrs Vanderbilt |
 | Maggie Steed als Mrs. James O'Flaherty |
 | Thelma Barlow als Mrs Oscar Garmunder |
| Liza Ross als Mrs EE Patterson |
 | Paola Dionisotti als Baroness Le Feyre |
 | Rhoda Lewis als Mrs Patsy Snow |
 | Aida Garifullina als Lily Pons |
| David Mills als Augustus Corbin |
 | David Menkin als Carlton Smith |
 | Sid Phoenix als Cpl. Jones |
 | Tunji Kasim als Pvt. Smith |
 | Carl Davis als Orlando Adams |
| Lloyd Hutchinson als Microphone Engineer |
| Richard Kilgour als Elevator Operator |
| Jonathan Plowright als Ernest Ziegler |
 | Josh O'Connor als Donaghy |
| Nat Luurtsema als Tallulah Bankhead |
 | Ewan Stewart als Colonel |
 | Cameron Cuffe als Gino |
 | John Guerrasio als News Vendor |
 | Elliot Levey als Edgar Booth Cunningham Jr |
 | Danny Mahoney als Clifford B. Thornton III |
 | Mark Arnold als Cole Porter |
| Stephen Frears | Writer |
| Stephen Frears | Director |
| Danny Cohen | Director of Photography |
| Nicholas Martin | Screenplay |
| Consolata Boyle | Costume Design |
| Ian Wilson | Supervising Sound Editor |
| Gemma McKeon | Digital Intermediate |
| Alan MacDonald | Production Design |
| Sue Hills | Script Supervisor |
| Jason Ewart | Additional Camera |
| Noga Alon Stein | Visual Effects Producer |
| Mike Dowson | Sound Re-Recording Mixer |
| Jo McLaren | Stunt Coordinator |
| Rosie Grant | Assistant Costume Designer |
| Iain Mackay | Camera Operator |
| Iain Struthers | First Assistant Camera |
| Phil Lee | Sound Effects Editor |
| Becki Ponting | Supervising Sound Editor |
| Manex Efrem | Special Effects Supervisor |
| Edd Gamlin | Visual Effects Editor |
| J. Roy Helland | Hairstylist |
| Christopher Wyatt | Art Direction |
| Marion Weise | Costume Supervisor |
| Andrea Cracknell | Hairstylist |
| Karen Elliott | Music Supervisor |
| Gareth Cousins | Art Direction |
| Eunice Huthart | Stunt Coordinator |
| Tracey Seaward | Producer |
| Lissy Holm | Casting |
| Jenny King | Visual Effects Coordinator |
| Michael Kuhn | Producer |
| Patrick Rolfe | Supervising Art Director |
| Lucy Bristow | Camera Operator |
| Anita Burger | Hairstylist |
| Karen Cohen | Makeup Artist |
| Leo Davis | Casting |
| Andrew Banwell | First Assistant Camera |
| Beverley Binda | Hairstylist |
| Rob Farris | Digital Intermediate |
| Ray Marston | Wigmaker |
| Aoife Warren | Assistant Art Director |
| Terry Davies | Music Director |
| Adam Gascoyne | Visual Effects Supervisor |
| Daniel Phillips | Makeup Designer |
| Valerio Bonelli | Editor |
| Tahira Herold | Makeup Artist |
| Karenjit Sahota | First Assistant Editor |
| Dafydd Archard | Sound Re-Recording Mixer |
| Daniel Phillips | Hair Designer |
| Patrick Malone | Digital Intermediate |
| Kathleen Chopin | Casting |
| Stuart Morton | Music Editor |
| Paul McGeachan | Gaffer |
| J. Roy Helland | Makeup Artist |
| Alexandre Desplat | Original Music Composer |
| Andrea King | Foley Artist |
| Elo Soode | Concept Artist |
| Elo Soode | Conceptual Design |
| Josh Wood | Carpenter |
