 | Matthew Perry als Alex Whitman |
 | Salma Hayek Pinault als Isabel Fuentes |
 | Jon Tenney als Jeff |
 | Carlos Gómez als Chuy |
 | Tomas Milian als Tomas Fuentes |
 | Siobhan Fallon Hogan als Lanie |
 | John Bennett Perry als Richard Whitman |
 | Stanley DeSantis als Judd Marshall |
 | Suzanne Snyder als Cathy Stewart |
 | Anne Betancourt als Amalia |
 | Jill Clayburgh als Nan Whitman |
 | Angelina Torres als Great Grandma |
| Debby Shively als Donna |
 | Mark Adair-Rios als Juan Fuentes |
| Annie Combs als Lisa Barnes |
 | Shelley Morrison als Aunt Carmen |
| María Cellario als Aunt Yolanda |
| Irene Hernández als Aunt Rosa |
 | Josh Cruze als Antonio Fuentes |
 | Angela Lanza als Petra |
| Randy Sutton als Dam Policeman |
 | Christopher Michael als Dam Policeman |
| Angel Valdez als Carlos |
| César Santana als Enrique |
 | Garret Davis als OSHA Rep |
 | Chris O'Neill als Priest |
| John Tripp als Man in Lobby |
 | Andrew Hill Newman als Assorted Cheeses |
 | Chris Bauer als Phil |
 | Douglas Weston als Hank |
| Rupert Baca als Porter |
| Jan Austell als Bruce Stewart |
| Cydney Arther als Deane Stewart |
 | Leslie Silva als Process Server |
 | Maryann Plunkett als Heliport Mother |
| Juel Mendel als Receptionist |
| Eddie Powers als Elvis |
| Salvador Saldaña als Mariachi Singer |
 | Robert Arevalo als Miguel Fuentes |
 | Beth Broderick als Tracey Verna (uncredited) |
 | Roger Anthony als Taxi Driver (uncredited) |
 | Mark Heenehan als Wedding Official (uncredited) |
| Jay So als Clubgoer (uncredited) |
| Robbie Greenberg | Director of Photography |
| Alan Silvestri | Original Music Composer |
| Juel Bestrop | Casting |
| Roger Bondelli | Editor |
| Katherine Reback | Screenplay |
| Doug Draizin | Producer |
| Andy Tennant | Director |
| Michael McDonnell | Executive Producer |
| Leslie Morales | Set Decoration |
| David Crank | Art Direction |
| Joan Taylor | Story |
| Katherine Reback | Story |
| Steven P. Saeta | Production Manager |
| Anna Maria Davis | Co-Producer |
| Steven P. Saeta | Associate Producer |
| Kimberly A. Tillman | Costume Designer |
| Edward Pisoni | Production Designer |
| Scott Printz | First Assistant Director |
| Steve Day | Second Assistant Director |
| James Ellis | Script Supervisor |
| Chris Hayes | Camera Operator |
| Billy Clevenger | First Assistant Camera |
| Karl Linde | Second Assistant Camera |
| LuEllyn Harper | Costume Supervisor |
| Virginia Burton | Costumer |
| Cathy Crandall | Costumer |
| Robin Siegel | Makeup Artist |
| Karen Blynder | Makeup Artist |
| Ermahn Ospina | Hairstylist |
| D.J. Plumb | Hairstylist |
| Melton C. Maxwell | Lighting Technician |
| Charles W. Sharp | Assistant Chief Lighting Technician |
| Rick A. Benedetto | Rigging Gaffer |
| Tim Ryan | Key Grip |
| Philip L. Brown | Best Boy Grip |
| David Fay | Dolly Grip |
| Peter J. Devlin | Sound Mixer |
| Scott Warren | Boom Operator |
| Robert Jauregui | Stunt Coordinator |
| Dennis Dion | Special Effects |
| Lois Walker | Production Coordinator |
| Erin Engman | Assistant Production Coordinator |
| Jan Clark | Production Accountant |
| Nicki McCain | Assistant Accountant |
| Jonathan T. Heath | Producer's Assistant |
| Randall Harris | Actor's Assistant |
| Juan Goldaracena | Actor's Assistant |
| James M. Morris | Location Manager |
| Michael Courville | Property Master |
| Jim Falkenstein | Assistant Property Master |
| Jonathan Bobbitt | Leadman |
| Alun Vick | Construction Coordinator |
| Bob Warner | Lead Painter |
| Evelyne Barbier | Set Designer |
| Dusty Saunders | Transportation Captain |
| Dan Brizendine | Transportation Co-Captain |
| Steven P. Saeta | Second Unit Director |
| Evelyn Purwins | First Assistant Editor |
| Kristine McPherson | Assistant Editor |
| Jeffrey Harlacker | Assistant Editor |
| Jeff Beattie | Assistant Editor |
| John Morris | Supervising Sound Editor |
| Richard Burton | Sound Editor |
| Michael Magill | Sound Editor |
| Hugo Weng | Sound Editor |
| Kimberly Lowe Voigt | Sound Editor |
| Tricia Linklater | First Assistant Sound Editor |
| Ali Derakhshan | Assistant Sound Editor |
| Bob Newlan | ADR Supervisor |
| Mary Andrews | ADR Editor |
| Mark Pappas | Foley Supervisor |
| Alicia Stevenson | Foley Artist |
| Scott Millan | Sound Re-Recording Mixer |
| Brad Sherman | Sound Re-Recording Mixer |
| Jim Fitzpatrick | Sound Re-Recording Mixer |
| Andrew Silver | Music Editor |
| Kenneth Bondy | Craft Service |
| Dirk Q. Long | Catering |
| Elliot Turner | Catering |
| Marilee Lear | Location Casting |
| Andy Spilkoman | Second Second Assistant Director |
| Louis Paul Tocchet | Production Assistant |
| Greg Abdulian | Production Assistant |
| Ramiro Adan Gómez | Production Assistant |
| Cora Lee Coomber | Production Assistant |
| Gabriela Gutentag | Unit Publicist |
| Frank Masi | Still Photographer |
| Chuck Southcott | Music Consultant |
| Donna Armstrong | Medical Consultant |
| Bob Putynkowski | Color Timer |
| Mo Henry | Negative Cutter |
| Edward Pisoni | Production Design |
| George Flores | Cableman |
