 | David Harbour als David Harbour III / David Harbour Jr. / Frankenstein |
 | Kate Berlant als Monica Fulton / Miss Machbeth |
 | Alex Ozerov-Meyer als Joey Vallejo / Sal |
 | Alfred Molina als Aubrey Fields / Captain |
 | Michael Lerner als Bobby Fox |
 | Mary Woronov als Nancy Erlich |
 | Marion Van Cuyck als Niece |
 | Lidia Porto als Detective Cepeda |
 | Randolph Thompson als Mr. Orlando |
 | Bridey Elliott als Reporter |
 | O-Lan Jones als Mother |
 | Heather Lawless als Doctor |
 | Graham Wagner als Graham |
| Marc Vietor als Voice Over (voice) |
| Justin Lieb | Production Design |
| Samy Burch | Casting |
| John Levenstein | Writer |
| Shawna Trpcic | Costume Design |
| Santiago Pedroza | Editor |
| David Harbour | Executive Producer |
| John Levenstein | Executive Producer |
| Andrea Steele | Makeup Department Head |
| Erin Owens | Producer |
| Nathan Reinhart | Producer |
| Mike Maltz | Art Direction |
| Daniel Gray Longino | Executive Producer |
| Daniel Gray Longino | Director |
| Carl Herse | Director of Photography |
| Ravi Nandan | Executive Producer |
| Inman Young | Executive Producer |
| Michael Penn | Original Music Composer |
| Jack Lewis | Set Decoration |
| Nina Adado | Hairstylist |
| Barney Burman | Special Effects Key Makeup Artist |
| Lara Cilento | Hair Department Head |
| Josie Peng | Hairstylist |
| Ted Pacult | Post Production Consulting |
| Erin Owens | Unit Production Manager |
| Roslyn Aronowitz | First Assistant Director |
| Cyndi Martin | Second Assistant Director |
| Jeffrey Pallotta | Second Second Assistant Director |
| Gerry Anderson | Prop Maker |
| Arvin Bautista | Graphic Designer |
| Ashley Bussell | Set Decoration Buyer |
| Richard Culligan | Leadman |
| John Dover | Set Dresser |
| Cameron Guignet | On Set Dresser |
| Lexi Langill | Graphic Designer |
| Siw Maretics | Scenic Artist |
| Pat Mars | Set Dresser |
| Cris Shapan | Graphic Designer |
| Timothy J. Smith | Construction Coordinator |
| Laura Solomon | Assistant Property Master |
| Mark Wolcott | Property Master |
| Jeremy Brill | Sound Mixer |
| John Chamberlin | Sound Re-Recording Mixer |
| Ben Greaves | Boom Operator |
| Sebastian Sheehan Visconti | Supervising Sound Editor |
| Iris von Hase | Utility Sound |
| Steve Shines | Special Effects Supervisor |
| Vanessa Portillo | Background Casting Director |
| Nila Neukum | Script Supervisor |
| Aldeme Mitchell | Costumer |
| Gina Pimentel | Costume Supervisor |
| Saivor Price | Tailor |
| Riley Adamson | Assistant Editor |
| Marissa Cattel | Post Production Supervisor |
| Scott Klein | Colorist |
| Nick Alvarado | Additional Gaffer |
| Jeff Bollman | Camera Operator |
| Jenn Cohen-Harrimon | Additional Gaffer |
| Tyler Condreay | Assistant Chief Lighting Technician |
| Tyler Condreay | Best Boy Electric |
| Dylan Conrad | Assistant Camera |
| Nicole Crivlare | Assistant Camera |
| Andrew Dickieson | Assistant Camera |
| Christopher Ford | Additional Gaffer |
| Alexander L. Gracie | Additional Gaffer |
| James Hansen | Grip |
| Devon Hoff-Weekes | Camera Operator |
| Tyler Johnson-Williams | Key Grip |
| Ryland Jones | Digital Imaging Technician |
| Kyle Kolding | Grip |
| Jennifer Lai | Assistant Camera |
| David Lanes | Grip |
| Garret Lara | Additional Gaffer |
| Andrew Petroski | Grip |
| Allyson Riggs | Still Photographer |
| Theodore Rysz III | Gaffer |
| Michael Schmidt | Additional Gaffer |
| Han Whitesides | Grip |
| Kevin Walters | Best Boy Grip |
| Daniel Vázquez | Grip |
| Grayson Venters | Grip |
| Daniel Vazquez | Dolly Grip |
| Devon Taaffe | Assistant Camera |
| Brian Sowell | Camera Operator |
| Andrew Simone | Additional Gaffer |
| Max Schwartz | Additional Gaffer |
| Max Schwartz | Lighting Technician |
| Joey Schmitz | Additional Gaffer |
| Katie Dormeier | Production Supervisor |
| Jillian Martelli | Production Coordinator |
| Kenneth "Luke" Worgan | Set Medic |
