 | Tupac Shakur als Ezekiel 'Spoon' Whitmore |
 | Tim Roth als Alexander 'Stretch' Rawland |
 | Thandiwe Newton als Barbara 'Cookie' Cook |
 | Charles Fleischer als Mr. Woodson |
 | Howard Hesseman als Blind Man |
 | Vondie Curtis-Hall als D-Reper |
 | John Sayles als Cop #1 |
 | Lucy Liu als Cee-cee |
 | Bokeem Woodbine als Mud (uncredited) |
 | Kasi Lemmons als Madonna |
 | Tom Towles als D-Reper's Henchman |
| Scott Kroopf | Executive Producer |
| Stewart Copeland | Original Music Composer |
| Vondie Curtis-Hall | Director |
| Paul Webster | Producer |
| Bill Pope | Director of Photography |
| Damian Jones | Producer |
| Vondie Curtis-Hall | Screenplay |
| Russell Simmons | Executive Producer |
| Christopher Koefoed | Editor |
| Erica Huggins | Producer |
| Ted Field | Executive Producer |
| Dan Perri | Title Designer |
| The Angel | Additional Music |
| Dan Bishop | Production Design |
