 | Jamie Lee Curtis als Laurie Strode / Keri Tate |
 | Josh Hartnett als John Tate |
 | Adam Arkin als Will Brennan |
 | Michelle Williams als Molly Cartwell |
 | Adam Hann-Byrd als Charles 'Charlie' Deveraux |
 | Jodi Lyn O'Keefe als Sarah Wainthrope |
 | LL Cool J als Ronald 'Ronny' Jones |
 | Janet Leigh als Norma Watson |
 | Joseph Gordon-Levitt als Jimmy Howell |
 | Branden Williams als Tony Allegre |
 | Matt Winston als Detective Matt Sampson |
 | Beau Billingslea als Detective 'Fitz' Fitzsimmons |
 | Larisa Miller als Claudia |
 | Emmalee Thompson als Casey |
 | John Cassini als Cop #1 |
 | Jody Wood als Cop #2 |
 | Chris Durand als Michael Myers |
 | Tom Kane als Dr. Sam Loomis (Voice) |
 | Nancy Stephens als Marion Chambers |
 | LisaGay Hamilton als Shirl (voice) |
 | Steve Miner als School Financial Advisor |
 | Tommy Lee Wallace als Michael Myers (archive footage) (uncredited) |
| Steve Miner | Director |
| Robert Zappia | Screenplay |
| Matt Greenberg | Screenplay |
| Moustapha Akkad | Executive Producer |
| John Ottman | Music |
| Daryn Okada | Director of Photography |
| Patrick Lussier | Editor |
| Paul Freeman | Producer |
| Malek Akkad | Associate Producer |
| Bob Weinstein | Co-Executive Producer |
| Harvey Weinstein | Co-Executive Producer |
| Kevin Williamson | Co-Executive Producer |
| Cary Granat | Executive Producer |
| Robert Zappia | Story |
| John Carpenter | Characters |
| Debra Hill | Characters |
| Ross Brown | Casting |
| Christine Sheaks | Casting |
| Mary West | Casting |
| John Willett | Production Design |
| Dawn Snyder | Art Direction |
| Wanda 'Beau' Peterson | Set Decoration |
| Deborah Everton | Costume Design |
| Ray McIntyre Jr. | Digital Effects Supervisor |
| Mark Cotone | First Assistant Director |
| Stephanie P. O'Brien | Second Assistant Director |
| Ed Gerrard | Music Supervisor |
| Frank E. Eulner | Sound Supervisor |
| Steve Boeddeker | Sound Designer |
| Donna Keegan | Stunt Coordinator |
| Marcia Holley | Stunts |
| Marguerite Happy | Stunts |
| Julie Michaels | Stunts |
| Laura Albert | Stunts |
| Richard E. Butler | Stunts |
| Brennan Dyson | Stunts |
| Gilbert B. Combs | Stunts |
| Casey Hotchkiss | Camera Operator |
| John Boccaccio | First Assistant Camera |
| James M. Tanenbaum | Sound Mixer |
| Ken Beauchene | Boom Operator |
| Todd Ellis | Property Master |
| Jeff Zucker | Gaffer |
| Mike Hodges | Key Grip |
| Carolyn Dessert | Costume Supervisor |
| Tania McComas | Key Makeup Artist |
| Voni Hinkle | Key Hair Stylist |
| Lisa Mozden | First Assistant Editor |
| Greg D'Auria | Assistant Editor |
| Isabel Henderson | Post Production Supervisor |
| Mable Lawson-McCrary | Script Supervisor |
| Paul Croghan | Production Coordinator |
| Jonathon Slator | Location Manager |
| April A. Janow | Production Accountant |
| Kiley Fascia | First Assistant Accountant |
| Nicola Goode | Still Photographer |
| Cassandra Kulukundis | Casting Associate |
| Tom Grode | Casting Assistant |
| Julie Glick | Key Costumer |
| Sonny Merritt | Set Costumer |
| Leah Brown | Set Costumer |
| Shari Perry | Assistant Hairstylist |
| Louis Lazzara | Assistant Makeup Artist |
| Tom Reta | Set Designer |
| Dawn Swiderski | Set Designer |
| John Hartigan | Special Effects Coordinator |
| Vince del Castillo | Transportation Coordinator |
| Brett F. Gates | Second Assistant Camera |
| Jacques Jouffret | Steadicam Operator |
| James F. Cornick | Rigging Gaffer |
| Jason D. Hodges | Dolly Grip |
| Brian Sata | Rigging Grip |
| Craig B. Ayers Sr. | Greensman |
| Bobby Joe Garren | Greensman |
| Richard Cody | Craft Service |
| Lora Hirschberg | Sound Re-Recording Mixer |
| Gary Rizzo | Sound Re-Recording Mixer |
| Chris Scarabosio | Sound Effects Editor |
| Ethan van der Ryn | Sound Effects Editor |
| Shannon Mills | Sound Effects Editor |
| Al Nelson | Sound Effects Editor |
| Andre Fenley | Sound Effects Editor |
| Marilyn McCoppen | ADR Supervisor |
| Claire Sanfilippo | Dialogue Editor |
| Sara Bolder | Dialogue Editor |
| Sandina Bailo-Lape | Foley Editor |
| Bruce Lacey | Foley Editor |
| Kent Sparling | Sound Mix Technician |
| Dennie Thorpe | Foley Artist |
| Jana Vance | Foley Artist |
| Tony Eckert | Foley Mixer |
| Frank 'Pepe' Merel | Foley Recordist |
| Casey Stone | Scoring Mixer |
| Amanda Goodpaster | Music Editor |
| David Slusser | Music Editor |
| Nina Saxon | Title Designer |
| Bob McMillian | Color Timer |
| Gary Burritt | Negative Cutter |
| Reid Paul | Digital Compositor |
| Eryn Krueger Mekash | Makeup Artist |
| Juliet Loveland | Makeup Artist |
| Brian Jennings | Visual Effects Supervisor |
