 | Winona Ryder als Veronica Sawyer |
 | Christian Slater als Jason 'J.D.' Dean |
 | Shannen Doherty als Heather Duke |
 | Lisanne Falk als Heather McNamara |
 | Kim Walker als Heather Chandler |
 | Penelope Milford als Pauline Fleming |
 | Glenn Shadix als Father Ripper |
 | Lance Fenton als Kurt Kelly |
 | Jennifer Rhodes als Veronica's Mom |
 | Jeremy Applegate als Peter Dawson |
 | Patrick Labyorteaux als Ram Sweeney |
| Jon Matthews als Rodney |
| Carrie Lynn als Martha Dunnstock / Dumptruck |
 | Phill Lewis als Dennis |
 | Renée Estevez als Betty Finn |
 | John Zarchen als Country Club Keith |
| William Cort als Veronica's Dad |
 | John Ingle als Principal Gowan |
| Stuart Mabray als Counselor Paul Hyde |
| Sherrie Wills als Country Club Courtney |
| Larry Cox als David |
| Kent Stoddard als Brad |
| Mark Carlton als Kurt's Dad |
| Curtiss Marlowe als Geek |
| Andrew Benne als Fat Cynic |
 | Kevin Hardesty als 1st Heavy Metaller in Pkg. Lot |
 | Josh Richman als 2nd Heavy Metaller in Pkg. Lot |
 | Bess Meyer als Female Stoner |
| Betty Ramey als Teacher in Conference Room |
 | Aaron Mendelsohn als Nerd in Pauline's Class |
 | Kirk Scott als Big Bud Dean |
 | Mark Bringelson als Officer McCord |
| Chuck Lafont als Officer Milner |
| Christie Mellor als Squealing Girl in Parking Lot |
| James 'Poorman' Trenton als 'Hot Probs' D.J |
| Adrian Drake als Gruff Teacher |
 | Craig Braginsky als Student (uncredited) |
| Michael Lindström als Student (uncredited) |
 | David McConnell als Student in the Gym (uncredited) |
| Mike Pont als Student in Cafeteria (uncredited) |
| Sylvia Tobias als Student (uncredited) |
 | Jeffrey Weissman als Voice Actor (uncredited) |
| Michael Lehmann | Director |
| Denise Di Novi | Producer |
| Daniel Waters | Screenplay |
| Francis Kenny | Director of Photography |
| Norman Hollyn | Editor |
| David Newman | Original Music Composer |
| Sally Dennison | Casting |
| Julie Selzer | Casting |
| Jon Hutman | Production Design |
| Kara Lindstrom | Art Direction |
| Rudy Dillon | Costume Design |
| Julie Hewett | Makeup Artist |
| Scott Williams | Hairstylist |
| Iya Labunka | Production Manager |
| Mary Ellen Woods | First Assistant Director |
| David W. Ford | Leadman |
| Greg J. Grande | Property Master |
| Don Larson Jr. | Construction Coordinator |
| George Berndt | ADR Editor |
| Sarah Goldsmith | Dialogue Editor |
| John Morris | Dialogue Editor |
| Lorie O'Shatz | Dialogue Editor |
| Jerry Ross | Supervising Sound Editor |
| Hamilton Sterling | Sound Effects Editor |
| Martin Bresin | Special Effects |
| Dan Bradley | Stunt Coordinator |
| Mitch Dubin | Camera Operator |
| Aristides Pappidas | Gaffer |
| Michael Paris | Still Photographer |
| Christopher Rogers | Dolly Grip |
| Thaddeus Wadleigh | Key Grip |
| Maureen Mitchell | First Assistant Editor |
| Jerry Ariganello | Location Manager |
| Scott Grusin | Music Editor |
| Claire Baker | Production Coordinator |
| Irene Brafstein | Studio Teachers |
| Elana Golden | Script Supervisor |
| Vicki Rocco | Production Coordinator |
| Christopher Webster | Executive Producer |
| Angela Moos | Makeup & Hair |
| Benita Allen | Second Assistant Director |
| Jeffrey Wetzel | Additional Second Assistant Director |
| Rick Bailey | Carpenter |
| Monti Santilli Rainbolt | Assistant Property Master |
| Dana Torrey | Assistant Art Director |
| Lori M. Turchin | Assistant Property Master |
| Rick Ash | Sound Re-Recording Mixer |
| James Ashwill | Foley Recordist |
| Douglas Axtell | Sound Mixer |
| Bob Baron | ADR Mixer |
| Kevin Bartnof | Foley Artist |
| Don Digirolamo | Sound Re-Recording Mixer |
| Ann Ducommun | Assistant Sound Editor |
| John Duvall | Foley Editor |
| Peter Friedberg | Assistant Sound Editor |
| Doug Hemphill | Sound Re-Recording Mixer |
| Ellen Heuer | Foley Artist |
| Chris Ingram | Assistant Sound Editor |
| Rob Scott | Boom Operator |
| Debbie Evans | Stunts |
| Joe Gilbride | Stunts |
| Jeff Habberstad | Stunts |
| Sandy J. Leavenworth | Stunts |
| Mitchell Amundsen | Focus Puller |
| Deirdre Arbucci | Second Assistant Camera |
| John G. Danza | Electrician |
| Ali Farboud | Electrician |
| Charley Gilleran | Assistant Chief Lighting Technician |
| Marc David Schultz | Electrician |
| John Schwartzman | Additional Camera |
| Lon Thompson | Electrician |
| Dennis Young | Electrician |
| Patrick Rush | Casting Associate |
| Sandra Araya Jensen | Costume Set Supervisor |
| Beverly Kline | Costumer |
| Lizz Wolf | Wardrobe Assistant |
| Dennis Brookins | Negative Cutter |
| Mike Milliken | Color Timer |
| Perry Patterson | Assistant Location Manager |
| Edward Flotard | Transportation Coordinator |
| Kimberly Edwards | Production Accountant |
| Caroline Pham | Assistant Production Coordinator |
| Bundy Chanock | Set Medic |
