 | Matthew Broderick als John Brown / Inspector Gadget / Robo Gadget |
 | Rupert Everett als Sanford Scolex / Dr. Claw |
 | Joely Fisher als Brenda / Robobrenda |
 | Michelle Trachtenberg als Penny |
 | Andy Dick als Kramer |
 | Cheri Oteri als Mayor Wilson |
 | Mike Hagerty als Sikes |
 | Dabney Coleman als Chief Quimby |
 | D.L. Hughley als Gadgetmobile (voice) |
 | René Auberjonois als Artemus Bradford |
 | Frances Bay als Thelma |
 | Mr. T als Himself |
 | Richard Kiel als Famous Big Guy with Silver Teeth |
 | Richard Lee-Sung als Famous Villain with Deadly Hat |
| Bobby Bell als Famous Identifier of Sea Planes |
| J.P. Manoux als Mayor's Sychophantic Assistant |
 | Brian George als Sore Guru |
 | Andy Heyward als Mr. D.I.C. - Party Guest |
 | Don Adams als Brain (voice) |
| Elise Horn als Pretty Girl |
| David Kellogg | Director |
| Dana Olsen | Story |
| Zak Penn | Screenplay |
| Kerry Ehrin | Story |
| Kerry Ehrin | Screenplay |
| Merrick Rustia | Visual Effects |
| Karin Silvestri | Stunts |
| John Debney | Music |
| Adam Greenberg | Director of Photography |
| Alan Cody | Editor |
| Thom Noble | Editor |
| Gerald B. Greenberg | Editor |
| Keii Johnston | Stunts |
| Amanda Mackey | Casting |
| Cathy Sandrich Gelfond | Casting |
| Peter Afterman | Music Supervisor |
| Lou Arkoff | Co-Producer |
| Jean Chalopin | Co-Producer |
| Richard R. Hoover | Visual Effects Supervisor |
| Stan Winston | Animatronics Designer |
| Mary E. Vogt | Costume Design |
| Michael White | Production Design |
| Leslie Dilley | Production Design |
| Jon Avnet | Executive Producer |
| Barry Bernardi | Executive Producer |
| Ralph Winter | Executive Producer |
| Aaron Meyerson | Executive Producer |
| Jonathan Glickman | Executive Producer |
| Jordan Kerner | Producer |
| Roger Birnbaum | Producer |
| Andy Heyward | Producer |
| Brian Smrz | Stunt Coordinator |
| Gregg Smrz | Stunt Coordinator |
| Lisa A. Becker | Production Supervisor |
| Geoff Hubbard | Supervising Art Director |
| Lawrence A. Hubbs | Art Direction |
| Bruton Jones | Art Direction |
| Kate J. Sullivan | Set Decoration |
| David Brace | Leadman |
| Nelson Bush | Swing |
| Alan Burg | Swing |
| Michael O'Donnell | Swing |
| Michael A. Belgrave | Swing |
| Bruce Bellamy | Swing |
| Sharron Reynolds-Enriquez | Script Supervisor |
| Roger Stevenson | Boom Operator |
| Cynthia Feyrer | Negative Cutter |
| Will Blount | Property Master |
| B. Ted Deiker | Production Coordinator |
| Daryl Kass | Unit Production Manager |
| Sergio Mimica-Gezzan | First Assistant Director |
| Sean Hobin | Second Assistant Director |
| Tom C. Peitzman | Visual Effects Producer |
| Robert Q. Mathews | Costume Supervisor |
| Ellen Ryba | Key Costumer |
| Dawn Y. Line | Costumer |
| Christina Smith | Makeup Supervisor |
| Barbara Lorenz | Hair Supervisor |
| Cynthia Barr | Makeup Artist |
| Michael Lorenz | Makeup Artist |
| Jacklin Masteran | Hairstylist |
| Susan Schuler-Page | Hairstylist |
| Craig Haagensen | Camera Operator |
| Michael D. Weldon | First Assistant Camera |
| Paul Santoni | Second Assistant Camera |
| Moshe Levin | "B" Camera Operator |
| Alan Cohen | First Assistant "B" Camera |
| Jeff Mart | Steadicam Operator |
| Gregory Lundsgaard | Steadicam Operator |
| Lisa Bonaccorso | Camera Loader |
| Tristan M. Brighty | First Assistant Editor |
| Kevin Greutert | First Assistant Editor |
| Bob Badami | Music Editor |
| Andrew Silver | Music Editor |
| Terry Porter | Sound Re-Recording Mixer |
| Mel Metcalfe | Sound Re-Recording Mixer |
| Dean A. Zupancic | Sound Re-Recording Mixer |
| Lon Bender | Sound Designer |
| Lon Bender | Sound Supervisor |
| Chris Jargo | ADR Supervisor |
| Dave McMoyler | ADR Supervisor |
| Craig S. Jaeger | Foley Supervisor |
| Christopher Assells | Sound Effects Editor |
| Scott Martin Gershin | Sound Effects Editor |
| Dan Hegeman | Sound Effects Editor |
| Philip A. Hess | Sound Effects Editor |
| Randy Kelley | Sound Effects Editor |
| Michael A. Reagan | Sound Effects Editor |
| Frank Smathers | Sound Effects Editor |
| Jon Title | Sound Effects Editor |
| Laura Graham | ADR Editor |
| Constance A. Kazmer | ADR Editor |
| Mary Andrews | ADR Editor |
| Richard Dwan Jr. | Dialogue Editor |
| Chris Hogan | Dialogue Editor |
| Lauren Stephens | Dialogue Editor |
| Gayle Wesley | First Assistant Sound Editor |
| David Stanke | Assistant Sound Editor |
| John Cannon | Assistant Sound Editor |
| Nerses Gezalyan | Foley Mixer |
| Greg Zimmerman | Foley Recordist |
| Doc Kane | ADR Mixer |
| Jeanette Browning | ADR Recordist |
| Steven C. McGee | Chief Lighting Technician |
| Kevin J. Lang | Best Boy Electric |
| Edward J. Cox | Electrician |
| Jerry Eubanks | Electrician |
| Jay Galbo | Electrician |
| Brian Tilden | Electrician |
| Don Tomich | Electrician |
| John Janusek | Key Grip |
| John P. Shine | Best Boy Grip |
| Michael C. Price | Dolly Grip |
| Scott Hillman | Key Rigging Grip |
| Christopher Raimo | Visual Effects Coordinator |
| Jason Roberts | Second Second Assistant Director |
| Peter Chesney | Special Effects Coordinator |
| Liz Ralston | Visual Effects Producer |
| Greg John Callas | Construction Coordinator |
| Lamonte Bell | Payroll Accountant |
| Gary Gillingham | Production Accountant |
| Deborah Simmrin | Unit Publicist |
| Frank Masi | Still Photographer |
| Ken Peterson | Transportation Coordinator |
| Josh Kuhn | Craft Service |
| Mary Beth Smith | Negative Cutter |
| Dana Ross | Color Timer |
| Gary Archer | Prosthetics |
| Adam Shankman | Choreographer |
| Leigh Hennessy | Stunt Double |
| Charlie Messenger | Extras Casting |
| Debbie Evans | Stunts |
| Bruno Bianchi | Characters |
| Andy Heyward | Characters |
| Jean Chalopin | Characters |
| Jill Brown | Stunt Double |
| Dane Farwell | Stunts |
| Jill Brown | Stunts |
| Seth Arnett | Stunts |
| Richard L. Blackwell | Stunts |
| Christopher 'Critter' Antonucci | Stunts |
| Ted R. Boyse | Stunts |
| John Branagan | Stunts |
| May Boss | Stunts |
| Richard E. Butler | Stunts |
| LaFaye Baker | Stunts |
| Keith Campbell | Stunts |
| Phil Chong | Stunts |
| Doc D. Charbonneau | Stunts |
| Douglas Crosby | Stunts |
| Gilbert B. Combs | Stunts |
| Charles Croughwell | Stunts |
| Tanner Gill | Stunts |
| Deborah Habberstad | Stunts |
| Jeff Habberstad | Stunts |
| Roy Farfel | Stunts |
| Tim Gallin | Stunts |
| Clay Donahue Fontenot | Stunts |
| Hubie Kerns Jr. | Stunts |
| Randy Hall | Stunt Double |
| Rosine 'Ace' Hatem | Stunts |
| Kim Robert Koscki | Stunts |
| Jake Lombard | Stunts |
| Johnny Martin | Stunts |
| Svetla Krasteva | Stunts |
| Mike H. McGaughy | Stunts |
| Cazimir Milostan | Stunts |
| Carol Neilson | Stunts |
| Carrick O'Quinn | Stunts |
| William Morts | Stunts |
| Carl Paoli | Stunts |
| Mick O'Rourke | Stunts |
| Michael Papajohn | Stunts |
| Walt Oggier | Stunts |
| Chad Parker | Stunts |
| Denney Pierce | Stunts |
| Janet Paparazzo | Stunts |
| Alan D. Purwin | Stunts |
| Jeff Podgurski | Stunts |
| Michael Russo | Stunts |
| Chris Sayour | Stunts |
| Ben Scott | Stunts |
| John-Clay Scott | Stunts |
| Myke Schwartz | Stunts |
| Rick Seaman | Stunts |
| Scott Sproule | Stunts |
| Shirley Smrz | Stunts |
| Erik Stabenau | Stunt Double |
| Mark Stefanich | Stunts |
| Lee Waddell | Stunts |
| Fred Waugh | Stunts |
| Mark Aaron Wagner | Stunts |
| P.K. West | Stunts |
| Darlene Ava Williams | Stunts |
| Big Daddy Wayne | Stunts |
| Keith Woulard | Stunts |
| Jake Brake | Stunts |
| Merritt Yohnka | Stunts |
| Debbie Evans | Stunt Double |
| Kim Robert Koscki | Stunt Driver |
