 | Andy García als Sgt. John Berlin |
 | Lance Henriksen als Sgt. Freddy Ross |
 | Uma Thurman als Helena Robertson |
 | Graham Beckel als John Taylor |
 | Kathy Baker als Margie Ross |
 | Kevin Conway als Chief Citrine |
 | John Malkovich als Agent St. Anne |
 | Perry Lang als Travis |
 | Nicholas Love als Bisley |
 | Michael O'Neill als Serato |
 | Paul Bates als Venables |
 | Bob Gunton als Goodridge |
 | Lenny Von Dohlen als Michael Blattis |
 | Debbon Ayer als Amanda |
 | Eddie Korbich als Myopic Janitor |
| Stephen Piemonte als Trimble |
 | Ken Camroux-Taylor als Pathologist |
 | Carol Schneider als Ann |
| Deborah Spector als Emerson |
 | Frank Birney als Expert |
 | Mike Winlaw als Male Reporter |
 | Jeffrey Josephson als Popeye |
| Thomas J. Hageboeck als Max |
| Jaylene Hamilton als Woman Reporter |
 | Joe Drago als St. Anne's Assistant |
| Jonas Quastel als Lab Technician |
| Charles Eaton als Airplane Pilot |
| Bryan Larkin als Bobby Ross (misspelled as "Bobby Rose" in end credits) |
| Bruce Robinson | Director |
| Bruce Robinson | Screenplay |
| Gary Lucchesi | Producer |
| Scott Rudin | Executive Producer |
| David Wimbury | Producer |
| Christopher Young | Original Music Composer |
| Conrad L. Hall | Director of Photography |
| Conrad Buff IV | Editor |
| Billy Hopkins | Casting |
| Suzanne Smith Crowley | Casting |
| Richard Macdonald | Production Design |
| Kacy Magedman | Art Department Coordinator |
| Judy L. Ruskin | Costume Design |
| Thomas Johnston | Script Supervisor |
| Buddy Joe Hooker | Stunt Coordinator |
| Brent Woolsey | Stunt Coordinator |
| Grace Gilroy | Unit Production Manager |
| Stephen Lim | Unit Production Manager |
| David B. Householter | First Assistant Director |
| Newt Arnold | First Assistant Director |
| Linda Brachman | Second Assistant Director |
| Jacob Rupp | Stunts |
| Gayle Hooker | Stunts |
| Fiona Roeske | Stunts |
| Alex Green | Stunts |
| Dawn Stofer-Rupp | Stunts |
| Mikka Dargel | Stunts |
| John C. Meier | Stunts |
| Tom Eirikson | Stunt Driver |
| Tom Glass | Stunt Driver |
| John Scott | Stunt Driver |
| William J. Durrell Jr. | Art Direction |
| John Willett | Art Direction |
| Casey Hallenbeck | Set Decoration |
| Elizabeth Wilcox | Set Decoration |
| Tony Guastella | Leadman |
| Beth Sterner | Supervising Sound Editor |
| Cecelia Hall | Supervising Sound Editor |
| Art Rochester | Sound Mixer |
| Juno J. Ellis | Supervising ADR Editor |
| Victoria Martin | Foley Supervisor |
| Barbara Harris | ADR Voice Casting |
| Clarinda Wong | First Assistant Editor |
| Rick Sharp | Makeup Artist |
| Jan Newman | Makeup Artist |
| KG Ramsey | Hairstylist |
| Patrick O'Brien | Hairstylist |
| Fraser Boyle | Grip |
| Theresa Repola Mohammed | Negative Cutter |
| Dan Curry | Title Designer |
| Brigitte Prochaska | Unit Publicist |
