 | Keanu Reeves als John Wick |
 | Common als Cassian |
 | Ian McShane als Winston |
 | Laurence Fishburne als Bowery King |
 | Riccardo Scamarcio als Santino D'Antonio |
 | Ruby Rose als Ares |
 | Lance Reddick als Charon |
 | Peter Stormare als Abram Tarasov |
 | Bridget Moynahan als Helen Wick |
 | Franco Nero als Julius |
 | John Leguizamo als Aurelio |
 | Claudia Gerini als Gianna D'Antonio |
 | Wass Stevens als Consiglieri |
 | Peter Serafinowicz als Sommelier |
 | Luca Mosca als Italian Tailor |
 | Tobias Segal als Earl |
 | Thomas Sadoski als Jimmy |
 | Chukwudi Iwuji als Mr. Akoni |
 | Yama als Sumo Assassin (uncredited) |
 | Erik Frandsen als Numismatic |
 | David Patrick Kelly als Charlie |
 | Perry Yung als Dr. Randall |
 | Youma Diakite als Lucia |
 | Midori Nakamura als Seamstress |
 | Mario Donatone als Cardinal |
| Giorgio Carminati als Priest |
 | Elli als Pawnbroker |
 | Thaddeus Daniels als Nigerian Man |
 | Margaret Daly als The Operator |
 | Christine Hollingsworth als Bartender |
 | Ciscandra Nostalghia als Concert Singer |
 | Vadim Kroll als Cheslav |
 | Simone Spinazzè als Cartographer |
 | Chris LaPanta als Earl's Guard #1 |
 | Guyviaud Joseph als Earl's Guard #2 |
| Diane Gooch als Waitress |
 | Alisa Ermolaev als Switchboard Operator #1 |
 | Kelly Rae LeGault als Switchboard Operator #2 |
 | Joan Smalls als Continental Female Assassin |
| Basil Iwanyk Sr. als Creepy Homeless Man |
 | Airon Armstrong als Ares Team #1 (uncredited) |
 | Nico Toffoli als Brian Blackman (uncredited) |
 | Aaron Cohen als Hitman (uncredited) |
 | Aly Mang als Winston's Personal Assistant (uncredited) |
 | Nora Sommerkamp als Hotel Guest - Assassin (uncredited) |
 | Marmee Regine Cosico als ND Chinatown Pedestrian (uncredited) |
 | Nancy Cejari als Business Woman (uncredited) |
| Kitty Crystal als Switch Board Operator (uncredited) |
 | Jennifer Dong als Cocktail Waitress (uncredited) |
 | Sidney Beitz als Bartender (uncredited) |
 | Mark Vincent als Winston's Guard (uncredited) |
 | Justin L. Wilson als Special Ops Assassin (uncredited) |
 | Shade Rupe als Opera Attendee (uncredited) |
 | Heidi Moneymaker als Assassin (uncredited) |
 | Angel Pai als Assassin (uncredited) |
 | Johnny Otto als Assassin (uncredited) |
 | Nobuya Shimamoto als Assassin (uncredited) |
 | Oleg Prudius als Russian Assassin (uncredited) |
 | Alex Ziwak als Russian Gunman (uncredited) |
 | Bruno Verdirosi als Gianna's Bodyguard (uncredited) |
 | Ottaviano Dell'Acqua als Gianna's Bodyguard (uncredited) |
 | Tim Connolly als Ares Team #2 (uncredited) |
 | Kenny Sheard als Ares Team #3 (uncredited) |
 | Stephen Dunlevy als Ares Team #4 (uncredited) |
 | Niko Nedyalkov als Metro Assassin #1 (uncredited) |
 | Bill Walters als Homeless Man in Chinatown (uncredited) |
| Claudia Delli Noci als Ballerina del locale |
| Chad Stahelski | Director |
| Evan Schiff | Editor |
| Kevin Kavanaugh | Production Design |
| Saverio Sammali | Art Direction |
| Chris Shriver | Art Direction |
| Luca Mosca | Costume Design |
| Letizia Santucci | Set Decoration |
| Jessica Kelly | Casting |
| Suzanne Smith Crowley | Casting |
| Robert Bernacchi | Executive Producer |
| Kevin Scott Frakes | Executive Producer |
| Basil Iwanyk | Producer |
| David Leitch | Executive Producer |
| Jennifer Madeloff | Associate Producer |
| Marco Valerio Pugini | Line Producer |
| Vishal Rungta | Executive Producer |
| Holly Rymon | Co-Producer |
| Chad Stahelski | Executive Producer |
| Jeff G. Waxman | Executive Producer |
| David Schlesinger | Set Decoration |
| Christian Giuliani | Art Department Coordinator |
| Sha-Sha Shiau | Art Department Coordinator |
| James Wendelken | Construction Coordinator |
| Kate Geller | Casting Associate |
| Eddie Grisco | Armorer |
| Shane B. Scott | Script Supervisor |
| Richard Henderson | Music Editor |
| Jen Monnar | Music Editor |
| John Houlihan | Music Supervisor |
| Brian Hemesath | Assistant Costume Designer |
| Jill Flowers | Costume Supervisor |
| Augusto Grassi | Costume Supervisor |
| Erick Martinez | Costume Supervisor |
| Alessia Pierantoni | Costume Coordinator |
| Carmia Marshall | Key Costumer |
| Paul Thompson | Key Costumer |
| Costanza Bastanti | Set Costumer |
| Zakiya Dennis | Set Costumer |
| Carmegie Dupuy | Set Costumer |
| Eldar Iskandarov | Set Costumer |
| Carlotta Moricci | Set Costumer |
| Lawrence Bell | Tailor |
| Chris Ebeling | Animation |
| Gregor Tavenner | Camera Operator |
| Robert Mattigetz | Second Unit Director of Photography |
| Duane Manwiller | Second Unit Director of Photography |
| Mark Schmidt | Steadicam Operator |
| Niko Tavernise | Still Photographer |
| Bill Almeida | Gaffer |
| Francesco Zaccaria | Gaffer |
| Clay Liversidge | Rigging Gaffer |
| Marco Sticchi | Rigging Gaffer |
| Craig Vaccaro | Rigging Grip |
| Michael A. McFadden | Rigging Grip |
| Fraser Taggart | Additional Photography |
| Claudio Del Gobbo | Dolly Grip |
| Chris DesRochers | Dolly Grip |
| Stefano Di Pasquali | Dolly Grip |
| Marque DeWinter | First Assistant Camera |
| Bradley Grant | First Assistant Camera |
| Roy Malhi | CG Supervisor |
| Maurizio Corridori | Special Effects Supervisor |
| R. Bruce Steinheimer | Special Effects Supervisor |
| Danilo Bollettini | Special Effects Coordinator |
| Rick Thompson | Special Effects Coordinator |
| Adam Pere | Visual Effects Coordinator |
| Michael Gilbert | Visual Effects Editor |
| Ryan Brassington | Visual Effects Editor |
| Molly Pabian | Visual Effects Producer |
| Carrie Richardson | Visual Effects Producer |
| Paul Linden | Visual Effects Supervisor |
| Mike F. Hedayati | Visual Effects Supervisor |
| John Stewart | Visual Effects Supervisor |
| D. Chris Smith | Sound Effects Editor |
| Andy Koyama | Sound Re-Recording Mixer |
| Martyn Zub | Sound Re-Recording Mixer |
| Kerrie Smith | Hair Department Head |
| Anna Hilton | Hairstylist |
| Susan Schectar | Hairstylist |
| Betsy Reyes | Key Hair Stylist |
| Stephen M. Kelley | Makeup Department Head |
| Joanna McCarthy | Key Makeup Artist |
| Ivy Ermert | Makeup Artist |
| Joseph Farulla | Makeup Artist |
| Sanja Milic | Makeup Artist |
| Anna Stachow | Makeup Artist |
| Rick Derby | First Assistant Editor |
| Chris Tonick | First Assistant Editor |
| Derek Kolstad | Writer |
| Elizabeth Zackheim | Dialect Coach |
| Shawn Sendio | Production Coordinator |
| Madison Lanting | Animal Wrangler |
| Kim Krafsky | Animal Wrangler |
| Carlos A. Garcia | Dialect Coach |
| Willy Faso | Production Coordinator |
| Yves Desjardins | Production Coordinator |
| John DeSimone | Production Supervisor |
| Carmela Compagnone | Production Accountant |
| Ami Cohen | Production Director |
| Jamie Buckner | Production Coordinator |
| Diana Ascher | Production Accountant |
| Marco Di Folco | Driver |
| Dan Hobert | Driver |
| Joanne Higginbottom | Score Engineer |
| Len Murach | Location Manager |
| Benoît Mathieu | Location Manager |
| Enrico Latella | Location Manager |
| Guy Efrat | Location Manager |
| Chris Cloud | Location Scout |
| Eric Van Dyn Hoven | Post Production Assistant |
| Kimberly Huston | Visual Effects Editor |
| Kevin Krout | Color Designer |
| Stephen F. Newnam | Production Controller |
| Kimi Rosenthal | Post-Production Manager |
| Matthew Evan Walsh | Post-Production Manager |
| Taylor White | Costume Coordinator |
| Simone Carlo Toniato Toso | Set Costumer |
| Monika Herédi | Set Dresser |
| Marc Désourdy | Stunt Coordinator |
| Jonathan Eusebio | Stunt Coordinator |
| Claudio Pacifico | Stunt Coordinator |
| J.J. Perry | Stunt Coordinator |
| Darrin Prescott | Stunt Coordinator |
| Jen Weissenberg | Stunts |
| PaiSen Wang | Stunts |
| Vencislav Stojanov | Stunts |
| Robbie P Smith | Stunts |
| Jim Ng | Stunts |
| Niko Nedyalkov | Stunts |
| Anthony N. | Stunts |
| Jason Mello | Stunts |
| Kyle Mclean | Stunts |
| Suo Liu | Stunts |
| Erica Kim | Stunts |
| Ryan Hanna | Stunts |
| Marco Lascari | Stunts |
| Gary Daniels | Stunts |
| Chino Binamo | Stunts |
| Daniel Bernhardt | Stunts |
| Krista Bell | Stunts |
| Stefanie Barry | Stunts |
| Calvin Ahn | Stunts |
| Andrea di Benedetto | Grip |
| Massimiliano Dessena | Grip |
| Mauro Faina | Grip |
| Marco Fabriziani | Drone Operator |
| Chloé Giroux-LaChance | First Assistant Camera |
| John Keating | Grip |
| Kelly Marroquin | Grip |
| Charlie Marroquin | Key Grip |
| Nicolas Marion | First Assistant Camera |
| Daniele Massaccesi | Camera Operator |
| Daniele Massaccesi | Steadicam Operator |
| Dustan Lewis McBain | Grip |
| Henri Normand | Lighting Technician |
| Lorenzo Peyrone | Grip |
| Frank Rinato | Camera Operator |
| Daniele Proietti | Drone Operator |
| Daniel Sauvé | Camera Operator |
| Fraser Taggart | Director of Photography |
| Stephen P. Cannon | Set Medic |
| Federica Durigon | Third Assistant Director |
| Ariane Collman | Third Assistant Director |
| Guy Efrat | Second Assistant Director |
| Alessandra Fortuna | Second Assistant Director |
| Jeremy Marks | Second Assistant Director |
| John R. Saunders | First Assistant Director |
| Luigi Spoletini | First Assistant Director |
| Simona Batistelli | Unit Manager |
| Alain Caporicci | Set Production Assistant |
| Vito Colazzo | Unit Production Manager |
| Andrea Pugini | Assistant Production Manager |
| Michael Tinger | Post Production Supervisor |
| Michael Tinger | Makeup Artist |
| Gillian Chandler | Key Makeup Artist |
| Marianne Bobet | Makeup Artist |
| Joe Barton | Location Scout |
| Ottaviano Dell'Acqua | Stunts |
| Daniel Hargrave | Stunts |
| Vinny Mazzarella | Property Master |
| Ken Goodstein | Property Master |
| Daniel Saxlid | Dialogue Editor |
| Duane Manwiller | Camera Operator |
| Tyler Bates | Original Music Composer |
| Joel J. Richard | Original Music Composer |
| Kerry Dean Williams | ADR Editor |
| Dan Laustsen | Director of Photography |
| Dan O'Connell | Foley Artist |
| Dawn Fintor | Foley Artist |
| John T. Cucci | Foley Artist |
| Alicia Stevenson | Foley Artist |
| David Jobe | Foley Mixer |
| Chris Navarro | ADR Mixer |
| Bruno Verdirosi | Stunts |
| Airon Armstrong | Stunts |
| Tim Connolly | Stunts |
| Kenny Sheard | Stunts |
| Stephen Dunlevy | Stunts |
| Jackson Spidell | Stunt Double |
| Cristina Onori | Supervising Art Director |
| Jeruschka Argenziano | Set Medic |
| Erica Lee | Producer |
| Long Qiuyun | Executive Producer |
| Robert Bernacchi | Unit Production Manager |
| Holly Rymon | Unit Production Manager |
| Darrin Prescott | Second Unit Director |
| Donna Sloan | Executive In Charge Of Production |
| Adam Hall | Grip |
| Heidi Moneymaker | Stunt Double |
| Heidi Moneymaker | Stunts |
| Derek Kolstad | Characters |
| Noon Orsatti | Stunts |
| Hannah Scott | Stunts |
| Jeremy Fry | Stunts |
| Todd Harris | Storyboard Artist |
| Allan Padelford | Stunts |
| David Swayze | Assistant Art Director |
