 | Daveigh Chase als Lilo (voice) |
 | Chris Sanders als Stitch / Leroy (voice) |
 | Tia Carrere als Nani (voice) |
 | Zoe Caldwell als Grand Councilwoman (voice) |
 | Kevin McDonald als Pleakley (voice) |
 | Kevin Michael Richardson als Gantu (voice) |
 | Rob Paulsen als Reuben (voice) |
 | Jeff Bennett als Hamsterviel (voice) |
 | David Ogden Stiers als Jumba (voice) |
 | Tara Strong als Angel / Belle / Houdini / Pleakley's GACC Assistant (voice) |
 | Debra Rogers als First Officer Ombit (voice) |
 | Ving Rhames als Cobra Bubbles (voice) |
 | Liliana Mumy als Mertle Edmonds (voice) |
 | Frank Welker als Sparky / Sprout / Mr. Stenchy / Kixx / Hoilo / Slugger (voice) |
 | Nancy Cartwright als Shortstuff / Phantasmo (voice) |
 | Bobcat Goldthwait als Nosy (voice) |
 | Doug Stone als Ensign Getco (voice) |
 | Tress MacNeille als Bonnie / Poxy / Gigi / Topper / Felix / Melty / Amnesio / Cannonball / GACC Van Computer (voice) |
 | Jim Cummings als Heckler (voice) (uncredited) |
 | Jillian Henry als Elena (voice) |
| Lili Ishida als Yuki (voice) |
 | Rocky McMurray als Clyde (voice) |
| Kali Whitehurst als Teresa (voice) |
| Roberts Gannaway | Writer |
| Roberts Gannaway | Director |
| Tony Craig | Director |
| José Zelaya | Character Designer |
| Jess Winfield | Writer |
| Dean DeBlois | Original Film Writer |
| Chris Sanders | Original Film Writer |
| J.A.C. Redford | Original Music Composer |
| Sy Thomas | Art Direction |
| Tony Mizgalski | Editor |
| Igor Khait | Line Producer |
| Kurt Weldon | Line Producer |
| Jess Winfield | Executive Producer |
| Tony Craig | Executive Producer |
| Roberts Gannaway | Executive Producer |
| Jamie Thomason | Casting |
| Dana Landsberg | Character Designer |
| Virginia Hawes | Character Designer |
| Greg Guler | Character Designer |
| Joe Chen | Animation Director |
| Jessie Xiong | Animation Director |
| Kirk Lin | Animation Director |
| Alice Hou | Animation Director |
| Marian Lin | Animation Director |
| Sparky Chen | Animation Director |
| Vincent Liu | Layout Supervisor |
| Suzanne Henderson Holmes | Production Coordinator |
| Mara Ancheta | Production Coordinator |
| Alex Teslik III | Supervising Technical Director |
| Otis Van Osten | Supervising Sound Editor |
| Jason Oliver | Supervising Dialogue Editor |
| Wes Otis | Sound Editor |
| Jeff Shiffman | Sound Editor |
| Allan K. Rosen | Supervising Music Editor |
| Jay Duerr | Supervising Music Editor |
| Scott Chan | Thanks |
| Eugene Pokihama | Thanks |
