 | Kodi Smit-McPhee als Owen |
 | Chloë Grace Moretz als Abby |
 | Richard Jenkins als The Father |
 | Elias Koteas als The Policeman |
 | Sasha Barrese als Virginia |
 | Dylan Kenin als Larry |
 | Dylan Minnette als Kenny |
 | Jimmy 'Jax' Pinchak als Mark |
 | Nicolai Dorian als Donald |
 | Seth Adkins als High School Kid |
 | Ritchie Coster als Mr. Zoric |
 | Cara Buono als Owen's Mother |
 | Chris Browning als Jack |
 | Rebekah Wiggins als Nurse |
 | Ashton Moio als Lanky Kid |
 | Gwendolyn Apple als Girl in Pool |
 | Brett DelBuono als Kenny's Brother |
| Colin Moretz als Video Arcade Counterman |
| Rowbie Orsatti als Scottie Tate |
 | Brenda Wehle als Principal |
| Galen Hutchison als Football Player #1 |
| Dean Satriano als Football Player #2 |
| Deborah L. Mazor als Day Nurse |
| Rachel Hroncich als Admitting Nurse |
| Matt Reeves | Screenplay |
| John Ajvide Lindqvist | Screenplay |
| John Ajvide Lindqvist | Novel |
| Matt Reeves | Director |
| Tobin Armbrust | Producer |
| Alexander Yves Brunner | Producer |
| Guy East | Producer |
| Donna Gigliotti | Producer |
| Carl Molinder | Producer |
| John Nordling | Producer |
| Simon Oakes | Producer |
| Philip Elway | Executive Producer |
| Fredrik Malmberg | Executive Producer |
| John Ptak | Executive Producer |
| Nigel Sinclair | Executive Producer |
| Michael Giacchino | Original Music Composer |
| Greig Fraser | Director of Photography |
| Stan Salfas | Editor |
| Avy Kaufman | Casting |
| Ford Wheeler | Production Design |
| Guy Barnes | Art Direction |
| Bradley Parker | Visual Effects Supervisor |
| Barbara Harris | Casting |
| Vicki Dee Rock | Co-Producer |
| Wendy Ozols-Barnes | Set Decoration |
| Janessa Bouldin | Additional Hairstylist |
| Tarra D. Day | Makeup Department Head |
| JoAnn Stafford-Chaney | Hair Department Head |
| Lelan Keffer | Set Dresser |
| Amahl Lovato | Set Designer |
| Jason Mack | Set Dresser |
| Rosario Provenza | Assistant Art Director |
| Will Files | Supervising Sound Editor |
| Will Files | Sound Re-Recording Mixer |
| Kim Foscato | Sound Editor |
| Rick Kline | Sound Re-Recording Mixer |
| Douglas Murray | Sound Re-Recording Mixer |
| Robert Shoup | Sound Editor |
| Korey J. Cauchon | Visual Effects Producer |
| Robin L. D'Arcy | Visual Effects Producer |
| Sean Andrew Faden | Visual Effects Supervisor |
| Erin Ferguson | Visual Effects Producer |
| Mark Owen Forker | Visual Effects Supervisor |
| Noel Hooper | Visual Effects Supervisor |
| Charlie Iturriaga | Visual Effects Supervisor |
| Christa Tazzeo | Visual Effects Producer |
| Mike Uguccioni | Visual Effects Supervisor |
| John Deering | Set Costumer |
| Roberta Souder Langhofer | Set Costumer |
| Daniela Moore | Costume Supervisor |
| Steven Lambert | Stunt Double |
| Al Goto | Utility Stunts |
| Angelique Midthunder | Utility Stunts |
| Emily Brobst | Stunt Double |
| Bobby Burns | Utility Stunts |
| Dana Reed | Stunt Double |
| John Robotham | Stunt Coordinator |
| Deborah L. Mazor | Stunts |
| Roger Stoneburner | Stunt Double |
| Rowbie Orsatti | Stunts |
| Ashton Moio | Stunts |
