 | Gian Maria Volonté als Charles 'Lucky' Luciano |
 | Edmond O'Brien als Commissioner Harry J. Anslinger |
 | Rod Steiger als Gene Giannini |
 | Vincent Gardenia als Colonel Charles Poletti |
 | Silverio Blasi als Italian Captain |
 | Charles Cioffi als Vito Genovese |
 | Larry Gates als Judge Herlands |
 | Magda Konopka als Contessa |
 | Jacques Monod als French Commissioner |
 | Karin Petersen als Igea Lissoni |
 | Dino Curcio als Don Ciccio |
| Charles Siragusa als Himself |
 | Aldo De Martino als (uncredited) |
| Francesco Rosi | Director |
| Piero Piccioni | Original Music Composer |
| Pasqualino De Santis | Director of Photography |
| Ruggero Mastroianni | Editor |
| Andrea Crisanti | Production Design |
| Marisa Crimi | Costume Design |
| Luciana Fortini | Costume Design |
| Franco Cristaldi | Producer |
| Francesco Rosi | Story |
| Francesco Rosi | Screenplay |
| Lino Iannuzzi | Screenplay |
| Gino Millozza | Production Manager |
| Gianni Arduini | First Assistant Director |
| Mico Galdieri | Second Assistant Director |
| Franca Invernizzi | Script Supervisor |
| Mario Cimini | Camera Operator |
| Giovanni Fiore Coltellacci | Assistant Camera |
| Gioacchino Tedeschi | Assistant Camera |
| Ezio Bellani | Assistant Camera |
| Sergio Strizzi | Still Photographer |
| Ferdinando Pescetelli | Sound |
| Franco Freda | Makeup Artist |
| Amato Garbini | Makeup Artist |
| Ada Palombi | Hairstylist |
| Gabriella Borzelli | Hairstylist |
| Mario Abussi | Production Assistant |
| Vittorio Bucci | Production Secretary |
| Gian Carlo Ciotti | Administration |
| Fiorangelo Plocco | Gaffer |
| Angelo Tiberti | Key Grip |
| Lea Mazzocchi | Assistant Editor |
| Stefano Patrizi | Assistant Editor |
| Gianni D'Amico | Sound Mixer |
| Antonio Sarno | Unit Manager |
| Tonino Guerra | Screenplay |
