 | Sigourney Weaver als Elizabeth Swados (voice) |
 | Steve Buscemi als Suicidal Thoughts (voice) |
 | Fred Armisen als Pill Bottle (voice) |
 | Dan Fogler |
 | Rachel Stern als Vocalist (singing voice) |
 | Joanna Bober |
| Hallie Cooper-Novack |
| Amanda Shechtman als Blonde Ponytail Girl (voice) |
 | Stephanie Hsu |
| Matthew Gehring |
| Elizabeth Swados | Director |
| Robert Marianetti | Director |
| Josh Hetzler | Producer |
| Sheila Nevins | Executive Producer |
| Roz Lichter | Producer |
| David Wachtenheim | Director |
| Sara Bernstein | Supervisor of Production Resources |
| Dave Nelson | Original Music Composer |
| Elizabeth Swados | Original Story |
| Robert Marianetti | Screenplay |
| David Wachtenheim | Screenplay |
| Elizabeth Swados | Screenplay |
| Elizabeth Swados | Musical |
| Sara Bernstein | Supervising Producer |
| Barbara Dobkin | Co-Executive Producer |
| Susan Whitehead | Co-Executive Producer |
| Kris Kukul | Keyboard Programmer |
| Jeremy Chatsky | Musician |
| Ed Levy | Musician |
| Rachel Stern | Vocals |
| Dave Man | Musician |
| Sean Lattrell | Storyboard |
| Glen Steinmacher | Storyboard |
| Sean Lattrell | Character Designer |
| David Wachtenheim | Character Designer |
| Robert Marianetti | Color Designer |
| Robert Marianetti | Background Designer |
| David Wachtenheim | Layout |
| Dan Madia | Animation |
| H. Stephen Mead | Animation |
| Ray Kosarin | Animation |
| Candy Kugel | Animation |
| Rick Broas | Animation |
| Andrew Kennedy | Animation |
| Willy Hartland | Animation |
| Frank Summers | Animation |
| Sean Lattrell | Animation |
| Mike Wetterhahn | Animation |
| Aidan Terry | Animation |
| Dale Clowdis | Compositor |
| Glen Scott | Online Editor |
| Timmy Quinn | Sound Assistant |
| Jennifer Michael | Foley |
| Rob Daly | Music Arranger |
| Rob Daly | Recording Supervision |
| Paul Michaels | Recording Supervision |
