 | Chevy Chase als Clark Griswold |
 | Beverly D'Angelo als Ellen Griswold |
 | Juliette Lewis als Audrey Griswold |
 | Johnny Galecki als Russell 'Rusty' Griswold |
 | John Randolph als Clark, Sr. |
 | Diane Ladd als Nora |
 | E.G. Marshall als Art |
 | Doris Roberts als Francis |
 | Randy Quaid als Cousin Eddie |
 | Miriam Flynn als Cousin Catherine |
 | Cody Burger als Rocky |
 | Ellen Hamilton Latzen als Ruby Sue |
 | William Hickey als Uncle Lewis |
 | Mae Questel als Aunt Bethany |
 | Sam McMurray als Bill |
 | Nicholas Guest als Todd Chester |
 | Julia Louis-Dreyfus als Margo Chester |
 | Nicolette Scorsese als Mary |
 | Keith MacKechnie als Delivery Boy |
 | Brian Doyle-Murray als Frank Shirley |
 | Natalija Nogulich als Helen Shirley |
 | Tony Epper als Bozo #1 |
| Billy Hank Hooker als Bozo #2 |
 | Alexander Folk als SWAT Officer |
 | Jeremy Roberts als Cop |
| Woody Weaver als Cop |
| Michael Kaufman als Young Executive |
| Doug Llewelyn als Parade Announcer (voice) |
| Devin Bailey als Clark (age 9) (uncredited) |
| Frank Foti Jr. als SWAT Team Sargeant (uncredited) |
| Traci Kochendorfer als Downtown Shopper (uncredited) |
| Jeremiah S. Chechik | Director |
| John Hughes | Screenplay |
| John Hughes | Producer |
| Tom Jacobson | Producer |
| Angelo Badalamenti | Original Music Composer |
| Thomas E. Ackerman | Director of Photography |
| Gerald B. Greenberg | Editor |
| Michael A. Stevenson | Editor |
| William S. Beasley | Associate Producer |
| Mauri Syd Gayton | Associate Producer |
| Matty Simmons | Executive Producer |
| Ramey E. Ward | Associate Producer |
| Daniel Grodnik | Executive Producer |
| Risa Bramon Garcia | Casting |
| Billy Hopkins | Casting |
| Heidi Levitt | Casting |
| Stephen Marsh | Production Design |
| Beala Neel | Art Direction |
| Lisa Fischer | Set Decoration |
| Michael Kaplan | Costume Design |
| Lee Harman | Makeup Artist |
| William S. Beasley | Unit Production Manager |
| Frank Capra III | Second Assistant Director |
| Barbara Adamski | Property Master |
| John Rozman | Leadman |
| David Baldwin | Sound Editor |
| Joe Gilbert | ADR Editor |
| Dan Hegeman | Sound Editor |
| Allen Hall | Special Effects |
| Gary L. Karas | Special Effects |
| Dieter Sturm | Special Effects |
| Chris Buchinsky | Visual Effects |
| Justin Klarenbeck | Visual Effects |
| Janet Brady | Stunts |
| Dick Ziker | Stunts |
| Matt Earl Beesley | First Assistant Director |
| Ron Payne | Music Supervisor |
| Douglas Knapp | Camera Operator |
| Marcia 'Mavis' Girard | Script Supervisor |
| James R. Alexander | Sound Mixer |
| Larry Kemp | Supervising Sound Editor |
| Wylie Stateman | Supervising Sound Editor |
| George H. Anderson | Sound Editor |
| Neal Burger | Sound Editor |
| Lou Kleinman | Sound Editor |
| Glenn T. Morgan | Sound Editor |
| Victoria Rose Sampson | Sound Editor |
| Mark P. Stoeckinger | Sound Editor |
| Stan Gilbert | Supervising ADR Editor |
| Jim Harrison | Music Editor |
| Ted Rhodes | Key Grip |
| Kaye Pownall | Hairstylist |
| David McCullough | Visual Effects |
| Charlie Picerni | Second Unit Director |
| Eric Engler | Second Unit Director of Photography |
| Stephen Robinette | Hairstylist |
| Bryan Denegal | Second Second Assistant Director |
| Vicki Jackson-Lemay | Second Second Assistant Director |
| Eric Jewett | Second Unit First Assistant Director |
| Glen Cooper | Standby Painter |
| Kenneth J. Gagnon Sr. | Construction Coordinator |
| David P. Newell | Assistant Property Master |
| Neil David Pontecorvo | Greensman |
| Richard Dean Rankin | Construction Coordinator |
| David J. Negrón Jr. | Production Illustrator |
| Timothy W. Tiedje | Property Master |
| S. Bruce Wineinger | Construction Coordinator |
| John Agalsoff Jr. | Cableman |
| Greg Agalsoff | Boom Operator |
| Rickley W. Dumm | Sound Effects Editor |
| Gary A. Hecker | Foley Artist |
| Doug Hemphill | Sound Re-Recording Mixer |
| Chris Jenkins | Sound Re-Recording Mixer |
| Mark Smith | Sound Re-Recording Mixer |
| Edward M. Steidele | Foley Artist |
| Karen Baker Landers | First Assistant Sound Editor |
| Dino DiMuro | Sound Effects Editor |
| Mark Lanza | Sound Effects Editor |
| Hoyt Yeatman | Visual Effects |
| Mark M. Pompian | Animation |
| Gregory J. Barnett | Stunts |
| William H. Burton Jr. | Stunts |
| Erik Cord | Stunts |
| Tim A. Davison | Stunts |
| Cheryl Wheeler Duncan | Stunts |
| Annie Ellis | Stunts |
| Jeannie Epper | Stunts |
| Sandra Lee Gimpel | Stunts |
| Harold Jones | Stunts |
| Steve Kelso | Stunts |
| Bill McIntosh | Stunts |
| John C. Meier | Stunts |
| Noon Orsatti | Stunts |
| Charlie Picerni | Stunt Coordinator |
| Steve Picerni | Stunts |
| Chad Randall | Stunts |
| John Robotham | Stunts |
| Philip Romano | Stunts |
| Sammy Thurman | Stunts |
| Scott Wilder | Stunts |
| Kenny Bates | Stunts |
| Leslie Hoffman | Stunt Double |
| Tommy J. Huff | Stunts |
| Jason White | Stunts |
| Mike Amorelli | Assistant Chief Lighting Technician |
| Craig Asato | Second Assistant Camera |
| Charles John Bukey | Best Boy Grip |
| Richmond G. Cogswell | Video Assist Operator |
| Kevin Kelley | Chief Lighting Technician |
| David L. Parrish | First Assistant Camera |
| Ron Phillips | Still Photographer |
| Scott M. Robinson | Key Grip |
| Bill Silic | Gaffer |
| Bill Silic | Chief Lighting Technician |
| Tama Takahashi | First Assistant Camera |
| John Wagner | Second Assistant Camera |
| Kurt Young | Dolly Grip |
| Kirk Bales | Assistant Camera |
| William Coss | First Assistant Camera |
| Albert Hood | Electrician |
| Ann Lukacs | Assistant Camera |
| Randy Nolen | Steadicam Operator |
| Ralph Eggleston | Animation |
| Tony Fucile | Animation |
| Bill Kroyer | Animation |
| Bob Scott | Animation |
| Dennis Venizelos | Animation |
| Dave Woodman | Animation |
| Juel Bestrop | Casting Assistant |
| Franklyn Warren | Extras Casting |
| Mari Grimaud | Costume Supervisor |
| Eddie Marks | Costume Supervisor |
| Cheryl Beasley Blackwell | Set Costumer |
| Kathryn Camp | Assistant Editor |
| Carlyn Montes De Oca | Assistant Editor |
| Thomas J. Busch | Location Manager |
| Stephen Andrzejewski | Assistant Location Manager |
| Robert C. Decker | Location Manager |
| Angelo Badalamenti | Orchestrator |
| Andrew Barrett | Orchestrator |
| Robert Fernandez | Scoring Mixer |
| Charles Samek | Orchestrator |
| Franklin Jones Jr. | Scoring Mixer |
| Shirley Walker | Conductor |
| Dan Marrow | Transportation Coordinator |
| Eileen Peterson | Unit Publicist |
