 | Tessa Thompson als Irene Redfield |
 | Ruth Negga als Clare Kendry |
 | André Holland als Brian Redfield |
 | Alexander Skarsgård als John Bellew |
 | Bill Camp als Hugh Wentworth |
 | Gbenga Akinnagbe als Dave |
 | Antoinette Crowe-Legacy als Felise |
 | Justus Davis Graham als Ted |
 | Ethan Barrett als Junior |
| Ashley Ware Jenkins als Zulena |
| Amos J. Machanic als Ralph Hazelton |
| Stu S. Becker als Cabbie |
 | Tom White als Attendant |
 | Margaret Daly als Woman #1 |
 | Kerry Flanagan als Woman #2 |
 | Buzz Roddy als Officer |
 | Derek Roberts als Guest |
| Amber Barbee Pickens als Dancer |
| Samuel Coleman als Dancer |
| Tatiana Marie Barber als Dancer |
| Carmen Carriker als Dancer |
| Leroy Church als Dancer |
| Brian Davis als Dancer |
| Zuri Foreman als Dancer |
| Abeni Jewel als Dancer |
| Malik Kitchen als Dancer |
| Ivan Phillip Owens als Dancer |
| Donna Hayes als Dancer (uncredited) |
| Shaun Hudson als Saxophone Player (uncredited) |
| Sienna Jeffries als Looper (uncredited) |
 | Doris McCarthy als Pedestrian (uncredited) |
| Rahim Rosen als Garbage Man (uncredited) |
| Rebecca Hall | Director |
| Nella Larsen | Novel |
| Margot Hand | Producer |
| Nina Yang Bongiovi | Producer |
| Forest Whitaker | Producer |
| Rebecca Hall | Producer |
| Devonté Hynes | Original Music Composer |
| Eduard Grau | Director of Photography |
| Sabine Hoffman | Editor |
| Nora Mendis | Production Design |
| Kristina Porter | Art Direction |
| Laura Rosenthal | Casting |
| Kim Ostroy | Casting |
| Paige Mitchell | Set Decoration |
| Marci Rodgers | Costume Design |
| Michael Y. Chow | Executive Producer |
| Lauren Dark | Executive Producer |
| Chaz Ebert | Executive Producer |
| David Gendron | Executive Producer |
| Arcadiy Golubovich | Executive Producer |
| Erika Hampson | Executive Producer |
| Erika Hampson | Line Producer |
| Ali Jazayeri | Executive Producer |
| Yvonne Huff | Executive Producer |
| Kevin M. Lin | Executive Producer |
| Christopher C. Liu | Executive Producer |
| Oren Moverman | Executive Producer |
| Dori A. Rath | Executive Producer |
| Joseph Restaino | Executive Producer |
| Marjorie Durand | Makeup Department Head |
| Jodi King | Key Makeup Artist |
| Toni Roman-Grimm | Hairstylist |
| Richard Baldomero | Boom Operator |
| Pam DeMetruis-Thomas | ADR Editor |
| Mark DeSimone | ADR Mixer |
| Paddy Hanlon | Sound Mixer |
| Branka Mrkic | Dialogue Editor |
| Jacob Ribicoff | Supervising Sound Editor |
| Jacob Ribicoff | Sound Re-Recording Mixer |
| Jacob Ribicoff | Sound Designer |
| Eric Strausser | Assistant Sound Editor |
| Jerrell Suelto | ADR Mixer |
| Eugene Hitt | Special Effects Supervisor |
| Bridget Fullan | Visual Effects |
| Alex Noble | Compositor |
| David Tecson | Visual Effects Supervisor |
| David Tecson | Associate Producer |
| Emma Cantor | Set Dresser |
| Alexandra Georgette Koskoris | Set Dresser |
| Madeline Rocco | Set Dresser |
| Rebecca Hall | Screenplay |
| Jennifer DiLullo | Post Production Supervisor |
| Vic Coram | Second Assistant Director |
| Alexis Vail | Second Second Assistant Director |
| Stephen Phelps | Property Master |
| Chris Cenatiempo | Stunt Coordinator |
| Stev Taylor | Wardrobe Supervisor |
| Ramsey Scott | Art Department Coordinator |
| Lori Abrams | Associate Producer |
| Ashley Foy | Sound |
