 | Zoe Colletti als Stella Nicholls |
 | Dean Norris als Roy Nicholls |
 | Michael Garza als Ramón Morales |
 | Gabriel Rush als Auggie Hilderbrandt |
 | Gil Bellows als Chief Turner |
 | Natalie Ganzhorn als Ruth Steinberg |
 | Austin Abrams als Tommy Milner |
 | Austin Zajur als Chuck Steinberg |
 | Kathleen Pollard als Sarah Bellows |
 | Lorraine Toussaint als Lou Lou |
 | Deborah Pollitt als Mrs. Steinberg |
 | Victoria Fodor als Mrs. Milner |
 | Marie Ward als Mrs. Hilderbrandt |
 | Mark Steger als Harold the Scarecrow / Pale Lady |
 | Javier Botet als Big Toe Corpse |
 | Troy James als Jangly Man |
| Will Corno als Mechanic |
 | Kyle Labine als Deputy Hobbs |
 | David Tompa als Doctor |
 | Karen Glave als Claire Baptiste |
 | Stephanie Belding als Reception Nurse |
| Hume Baugh als Deodat Bellows |
 | Jane Moffat als Delanie Bellows |
 | Will Carr als Ephraim Bellows |
| Amanda Smith als Gertrude Bellows |
| Brandon Knox als Harold Bellows |
 | Rodrigo Fernandez-Stoll als Drive-in Manager |
| Anna Fraser als Actress |
 | Alex Spencer als Orderly #1 |
 | Matthew Smith als Mr. Steinberg |
 | Daniel Gravelle als Letterman #1 |
 | Colton Gobbo als Letterman #2 |
| Ajanae Stephenson als Lou Lou (8 Yrs.) |
| Divan Meyer als Student (uncredited) |
 | Lyndon B. Johnson als Himself (archive footage) |
 | Richard Nixon als Himself (archive footage) |
 | Walter Cronkite als Himself (archive footage) |
| Elizabeth Grave | Producer |
| Roberto Grande | Executive Producer |
| Guillermo del Toro | Producer |
| Joshua Long | Executive Producer |
| Jason F. Brown | Producer |
| Sean Daniel | Producer |
| André Øvredal | Director |
| Kevin Hageman | Screenplay |
| Dan Hageman | Screenplay |
| Rich Delia | Casting Director |
| Roman Osin | Director of Photography |
| Patrick Larsgaard | Editor |
| David Brisbin | Production Design |
| Patricia Larman | Set Decoration |
| Marco Beltrami | Original Music Composer |
| J. Miles Dale | Producer |
| Anna Drubich | Original Music Composer |
| Howard Paar | Music Supervisor |
| J. Miles Dale | Unit Production Manager |
| Regina Robb | Production Manager |
| Tyler Delben | Second Assistant Director |
| Myron Hoffert | First Assistant Director |
| Ruth Myers | Costume Designer |
| Peter Luo | Executive Producer |
| Alex Ginno | Executive Producer |
| Michael L. Hall | Gaffer |
| Darren McGuire | Stunt Coordinator |
| Tyler Whitam | Sound Editor |
| Steve Hammond | Foley Artist |
| J.R. Fountain | Supervising Sound Editor |
| Joe Dzuban | Sound Designer |
| Geoff Hill | Special Effects Coordinator |
| George Kraychyk | Still Photographer |
| Etienne Gravrand | Set Designer |
| Nic Osborne | Second Unit Director |
| Erika Schengili-Roberts | Sound Mixer |
| Mike Woroniuk | Sound Re-Recording Mixer |
| Cliona Furey | Hair Department Head |
| Glen Gauthier | Sound Mixer |
| Mary Arthurs | Property Master |
| Zhitang Chen | Co-Executive Producer |
| Colin Penman | Makeup Department Head |
| Dug Rotstein | Script Supervisor |
| Colin Hoult | Second Unit Director of Photography |
| Brandt Gordon | Art Direction |
| Greg Chapman | Sound Mixer |
| Jill Purdy | Supervising Sound Editor |
| Sorin Popescu | Set Designer |
| Andrew Tay | Sound Re-Recording Mixer |
| Steve Medeiros | Sound Editor |
| Daniel McGraw | Makeup Artist |
| Rob Ballantyne | Storyboard Artist |
| Dusty Reeves | Art Department Coordinator |
| Mia Sturup | Assistant Costume Designer |
| Jane Flanders | Costume Supervisor |
| Trason Fernandes | Key Makeup Artist |
| Jacqueline Robertson Cull | Key Hair Stylist |
| Cheryl Ross | Assistant Hairstylist |
| Gilles Corbeil | "A" Camera Operator |
| Gilles Corbeil | Steadicam Operator |
| Doug Lavender | First Assistant "A" Camera |
| Anton Van Rooyen | "B" Camera Operator |
| Mark Cyre | First Assistant "B" Camera |
| Spencer Gray | Digital Imaging Technician |
| Douglas Wilkinson | Post Production Supervisor |
| Alexandra Anger | Contact Lens Technician |
| Andrea Brown | Assistant Makeup Artist |
| Kevin Carter | Contact Lens Painter |
| Alanna Dickie | Contact Lens Technician |
| Shadi Enayati | Post-Production Manager |
| Jack Schuster | Executive In Charge Of Post Production |
| Mario C. Cacioppo | Assistant Director |
| Janine Fung | Third Assistant Director |
| Rory James | Assistant Director |
| Mark Lukac | First Assistant Director |
| Missy Morris | Third Assistant Director |
| Nicholas Müller-Osborne | Second Unit Director |
| Lauren Batcher | Set Dresser |
| Everett Biggar | Assistant Property Master |
| Steve Bryant | Set Dresser |
| Heather Carlson | Graphic Designer |
| Linda Cheung | Set Dresser |
| David Gruer | Set Decoration Buyer |
| Alex Hadjiantoniou | Storyboard Artist |
| Owain Harris | Carpenter |
| John Hinz | Set Dresser |
| Jonathan Kovacs | Set Dresser |
| Simon March | Set Dresser |
| Ryan McCaffrey | Set Dresser |
| Alexander Narizni | Set Dresser |
| Vincent Proce | Concept Artist |
| Victor 'Chikko' Quon | Key Scenic Artist |
| Mauricio Ruiz | Concept Artist |
| Theresa Shain | Graphic Designer |
| Tija Smith | Props |
| Nicole Stephenson | Assistant Property Master |
| Peter C. Strange | Set Dresser |
| Phillip Tellez | Construction Coordinator |
| German Camardella | ADR Editor |
| Bill Higley | ADR Mixer |
| Bobby Johanson | ADR Mixer |
| Ihor Kaniuk | Sound Re-Recording Mixer |
| Paul Lynch | ADR Recordist |
| Claudia Pinto | First Assistant Sound Editor |
| Jeffrey Roy | ADR Mixer |
| Michael Lee Taylor | Boom Operator |
| Tyler Whitham | Sound Effects Editor |
| Laura Kennedy | Special Effects Technician |
| Tim Phoenix | Special Effects |
| Ameya Adchule | Digital Compositor |
| Matthew Beightol | Compositor |
| Barb Benoit | Digital Compositor |
| Dennis Berardi | Senior Visual Effects Supervisor |
| Lucian Boicu | Compositing Supervisor |
| J. Alan Bradshaw | CG Supervisor |
| Cristian Camaroschi | CG Supervisor |
| Andrew Carruthers | Visual Effects Coordinator |
| Colleen Catton | Compositor |
| Yuting Chen | Digital Compositor |
| Chris Hagfors Dahlmo | Digital Compositor |
| Markus Dahlstrøm | Digital Compositor |
| Jyoti Bhalchandra Deshpande | Visual Effects Production Manager |
| Sagar Dhondge | Compositor |
| Bhardwaj Divyanshu | Visual Effects |
| Patrick Melton | Screenstory |
| Marcus Dunstan | Screenstory |
| Guillermo del Toro | Screenstory |
| Alvin Schwartz | Book |
