 | Neve Campbell als Sidney Prescott |
 | Courteney Cox als Gale Weathers |
 | Skeet Ulrich als Billy Loomis |
 | Rose McGowan als Tatum Riley |
 | David Arquette als Dewey Riley |
 | Matthew Lillard als Stu Macher |
 | Jamie Kennedy als Randy Meeks |
 | W. Earl Brown als Kenny Brown |
 | Joseph Whipp als Sheriff Burke |
 | Liev Schreiber als Cotton Weary |
 | Drew Barrymore als Casey Becker |
 | Roger L. Jackson als Ghostface (voice) |
 | Kevin Patrick Walls als Steven Orth |
 | David Booth als Casey's Father |
| Carla Hatley als Casey's Mother |
 | Lawrence Hecht als Neil Prescott |
| Lois Saunders als Mrs. Tate |
| Lisa Beach als TV Reporter #1 |
| Tony Kilbert als TV Reporter #2 |
 | C.W. Morgan als Hank Loomis |
 | Frances Lee McCain als Mrs. Riley |
| Troy Bishop als Expelled Teen #1 |
 | Ryan Kennedy als Expelled Teen #2 |
| Leonora Scelfo als Cheerleader in Bathroom |
| Nancy Anne Ridder als Girl in Bathroom |
 | Lisa Canning als Reporter with Mask |
| Bonnie Wood als Young Girl in Video Store |
| Aurora Draper als Party Teen #1 |
| Kenny Kwong als Party Teen #2 |
| Justin Sullivan als Teen on Couch |
| Kurtis Bedford als Bored Teen |
| Angela Miller als Girl on Couch |
 | Henry Winkler als Principal Arthur Himbry (uncredited) |
 | Linda Blair als Obnoxious Reporter (uncredited) |
 | Wes Craven als Fred the Janitor (uncredited) |
| Matt McDonald als Video Customer (uncredited) |
| Freddy W. Smith als Hall Monitor (uncredited) |
| Wes Craven | Director |
| Kevin Williamson | Screenplay |
| Cathy Konrad | Producer |
| Marianne Maddalena | Executive Producer |
| Bob Weinstein | Executive Producer |
| Harvey Weinstein | Executive Producer |
| Cary Woods | Producer |
| Marco Beltrami | Original Music Composer |
| Mark Irwin | Director of Photography |
| Patrick Lussier | Editor |
| Lisa Beach | Casting |
| Bruce Alan Miller | Set Designer |
| David Lubin | Art Direction |
| Michele Poulik | Set Decoration |
| Stuart M. Besser | Co-Executive Producer |
| Dixie J. Capp | Co-Producer |
| Cynthia Bergstrom | Costume Design |
| James Burke | Greensman |
| Nicholas Mastandrea | Associate Producer |
| Bruce Alan Miller | Production Design |
| Gerald Lehtola | Art Department Coordinator |
| Mathew Hooey | Costume Supervisor |
| Gary J. Saldutti | Costume Supervisor |
| Annie Welles | Script Supervisor |
| Richard Bryce Goodman | Sound Mixer |
| Tom E. Dahl | Sound Re-Recording Mixer |
| Rick Alexander | Sound Re-Recording Mixer |
| Leslie Shatz | Sound Re-Recording Mixer |
| Sam Gemette | Sound Effects Editor |
| Scott A. Tinsley | Sound Effects Editor |
| Sean Rush | Boom Operator |
| Frank Ceglia | Special Effects Supervisor |
| Jeff Rabhan | Music Supervisor |
| E. Gedney Webb | Music Editor |
| David Moir | Still Photographer |
| Dan Kneece | Steadicam Operator |
| Kirk R. Gardner | Steadicam Operator |
| Mark Van Loon | Steadicam Operator |
| Robert J. Carlyle | Construction Coordinator |
| Robert Burg | Painter |
| Victoria Carlson | Standby Painter |
| Scott Andrew Ressler | First Assistant Camera |
| Joseph J. Allen | Grip |
| Lynn Marie Curreri | Hairstylist |
| Barbara Olvera | Key Hair Stylist |
| Karen Bradley | Makeup Artist |
| Lori Harrison | Set Dressing Artist |
| Craig Braginsky | Additional Music |
| Braxton Bragg | Carpenter |
| Mary Ellen Leonard | Craft Service |
| Moore Brian | Driver |
| Ryan Krayser | Post Production Assistant |
| Daniel K. Arredondo | Post Production Supervisor |
| Dean Wright | Production Office Coordinator |
| J.P. Jones | Property Master |
| Steve Kohler | Sound Recordist |
| Theresa Donahoe | Stand In |
| Anthony Cecere | Stunt Coordinator |
| J.T. Thayer | Transportation Captain |
| Derek Raser | Transportation Coordinator |
| Stuart M. Besser | Unit Production Manager |
| Claire Raskind | Unit Publicist |
| Doug Hunt | Video Assist Operator |
| Nicholas Mastandrea | First Assistant Director |
| Mike Mertens | Color Timer |
| Peter Devaney Flanagan | First Assistant Editor |
| Jason Boccaleoni | Lighting Technician |
| Ron Diggory | Rigging Grip |
| Cary Granat | Executive In Charge Of Production |
| Eric Klosterman | Location Manager |
| David Crockett | Production Accountant |
| John K. Adams | ADR Supervisor |
| Pete Anthony | Orchestrator |
| Marla McGuire | Dialogue Editor |
| Bob Goold | Dialogue Editor |
| John O. Wilde | Dialogue Editor |
| Vic Radulich | Dialogue Editor |
| Pat Somerset | ADR Editor |
| Ricki Fournier | Costumer |
| Lucille OuYang | Second Assistant Director |
| Daniel K. Arredondo | Second Second Assistant Director |
| John 'Skip' Weaver | Assistant Property Master |
| Lori Harrison | Property Buyer |
| Beau Biggart | ADR Mixer |
| Roy Baker | Foley Artist |
| Paul Benedici | Foley Mixer |
| Tom Ketterer | Sound Assistant |
| Paul B. Clay | Sound Supervisor |
| Deborah Alexander-Lee | Stunt Double |
| Peter Deming | Additional Director of Photography |
| Don Starnes | BTS Videographer |
| Egor Davidoff | Camera Loader |
| Charles J. Schray | Dolly Grip |
| Charles M. Smallwood | First Company Grip |
| Jeffrey N. Civa | Second Assistant Camera |
| Kevin Ball | Second Company Grip |
| Barbara Harris | ADR Voice Casting |
| Sarah Katzman | Casting Assistant |
| Paul Kieran | Assistant Editor |
| Thomas M. Harrigan | Assistant Location Manager |
| Michael D. Gillis | Location Assistant |
| Marco Beltrami | Conductor |
| Ed Gerrard | Music Consultant |
| Charlene Barr | Art Department Production Assistant |
| Scott Medcalf | Assistant Chief Lighting Technician |
| Jay W. Yowler | Chief Lighting Technician |
| Paul Boettiger | Production Assistant |
| Katherine Zilavy | Production Secretary |
| Stan Fiferman | Foley Artist |
| Lee Tinkham | ADR Mixer |
| Tim Boyle | Scoring Mixer |
| James Marlowe | Location Scout |
| Melanie Levitt | Makeup Artist |
| Kris Ravetto | Makeup Artist |
| Andrew Durham | Assistant Production Coordinator |
| Lynn Salvatori | Stunts |
| Kathy Marshall | Stunts |
| Christine Anne Baur | Stunts |
| Dane Farwell | Stunts |
