 | Steve Carell als Dodge Petersen |
 | Keira Knightley als Penelope "Penny" Lockhart |
 | Connie Britton als Diane |
 | Rob Corddry als Warren |
 | Adam Brody als Owen |
 | Derek Luke als Alan Speck |
 | Martin Sheen als Frank Petersen |
 | Melanie Lynskey als Karen Amalfi |
 | Nancy Carell als Linda Petersen |
 | William Petersen als Trucker |
 | Gillian Jacobs als Waitress / Katie |
 | T.J. Miller als Chipper Host / Darcy |
 | Patton Oswalt als Roache |
 | Bob Stephenson als Officer Wally Johnson |
 | Brad Morris als Radio Announcer (voice) |
 | Mark Moses als Anchorman |
 | Roger Aaron Brown als Alfred |
 | Rob Huebel als Jeremy |
 | Trisha Gorman als Crying Woman |
 | Tonita Castro als Elsa |
 | Leslie Murphy als Amy |
 | Kasey Campbell als Danny |
 | Vince Grant als Man #1 / Chip |
 | Amy Schumer als Woman #1 / Lacey |
 | Marshall Manesh als Indian Man |
| Aleister als Sorry |
 | Rene Gube als Cell-Mate |
 | Jim O'Heir als Cop #2 |
| Daniel Maurio als Toilet Guy |
 | Matthew Alan Brady als Kissing Couple In Park (uncredited) |
| Tony Brown als Gay Party Guest (uncredited) |
| Lauren Crawford als Bikini Girl (uncredited) |
| Laura Mann als Sarah (uncredited) |
| Prestin Persson als Bikini Girl (uncredited) |
| Lauren K. Solomon als Kissing Friendsy's Customer (uncredited) |
 | Chris Spinelli als Cyclist (uncredited) |
| Hannah Victoria Stock als Party Girl (uncredited) |
| Steve Golin | Producer |
| Lorene Scafaria | Director |
| Lorene Scafaria | Screenplay |
| Mark Roybal | Producer |
| Steven M. Rales | Producer |
| Joy Gorman Wettels | Producer |
| Nicole Abellara Hallman | Casting |
| Jonathan Sadoff | Music |
| Kristin M. Burke | Costume Design |
| Chris L. Spellman | Production Design |
| Jeanne McCarthy | Casting |
| Kathy Lucas | Set Decoration |
| Jeanne Van Phue | Makeup Department Head |
| Rob Simonsen | Music |
| Tim Orr | Director of Photography |
| Brian Wittle | Boom Operator |
| Donald Frazee | Special Effects Coordinator |
| Paul Horn | Camera Operator |
| Adam C. Eichhorst | Dolly Grip |
| Richard Dwan Jr. | Supervising Dialogue Editor |
| John Ryan | Visual Effects Supervisor |
| Mark Sahagun | Digital Intermediate |
| Nick Neutra | Foley |
| David LeRoy Anderson | Makeup Artist |
| Kevin Zimmerman | First Assistant Sound Editor |
| George Santo Pietro | Dolly Grip |
| Heidi Higginbotham | Costume Supervisor |
| Timothy P. Salmon | Boom Operator |
| Alan Jacoby | Camera Operator |
| Matthew Coleman | Best Boy Electric |
| Richard Dwan Jr. | Sound Editor |
| Trevor Metz | Sound Effects Editor |
| Randy L. Childs | Construction Coordinator |
| Jonathon Bradley | Chief Lighting Technician |
| Angela Gurule | Key Hair Stylist |
| Sharon C. Dietz | Production Manager |
| John McKeown | First Assistant Director |
| Perry Robertson | Supervising Sound Editor |
| Greg Mitchell | Video Assist Operator |
| Ronald De Torres | Lighting Technician |
| Peter Tothpal | Key Hair Stylist |
| Dori Hana Scherer | Art Department Assistant |
| John Joseph Minardi | Key Grip |
| Dayna Pink | Costume Design |
| Jon Mooney | Music Editor |
| Cynthia Kershaw | Art Department Coordinator |
| Ken Strain | Boom Operator |
| J. David Everhart | Visual Effects Producer |
| Shane Buttle | Lighting Technician |
| Sarah Clifford | Animal Coordinator |
| Roxane Griffin | Key Hair Stylist |
| Sean Lira | Set Dresser |
| James Wright | Dolby Consultant |
| Noel Vought | Foley |
| Eve Streger | Casting Assistant |
| Leighton Bowers | Assistant Costume Designer |
| Matthew A. Petrosky | Steadicam Operator |
| Jan Rudolph | Script Supervisor |
| Kym Langlie | Unit Publicist |
| Gay Perello | Property Master |
| Denise Woodgerd | Digital Intermediate |
| Gary J. Wayton | Stunt Coordinator |
| Nathan Kahane | Executive Producer |
| Nicole Brown | Executive Producer |
| Zene Baker | Editor |
| Monica Staggs | Stunts |
