 | Will Smith als Lance Sterling (voice) |
 | Tom Holland als Walter Beckett (voice) |
 | Ben Mendelsohn als Killian (voice) |
 | Rashida Jones als Marcy Kappel (voice) |
 | Karen Gillan als Eyes (voice) |
 | DJ Khaled als Ears (voice) |
 | Reba McEntire als Joyless (voice) |
 | Rachel Brosnahan als Wendy (voice) |
 | Masi Oka als Kimura (voice) |
 | Carla Jimenez als Geraldine (voice) |
 | Mark Ronson als Agency Control Room Technician (voice) |
 | Toru Uchikado als Yakuza #1 (voice) |
 | Hisato Masuyama als Yakuza #2 (voice) |
 | Toshiya Agata als Yakuza #3 (voice) |
| Michi Yamato als Yakuza #4 (voice) |
| Hiroshi Otaguro als Yakuza #5 (voice) |
| Claire Crosby als Unitee (voice) |
| Jarrett Bruno als Young Walter / Pigeon Voice (voice) |
 | Tawny Newsome als Agency Employee #1 (voice) |
 | JB Blanc als Agency Employee #2 / Marcy's Agent #3 (voice) |
 | Adrian Gonzalez als Agency Employee #3 / Marcy's Agent #1 (voice) |
 | William-Christopher Stephens als Agency Employee #4 / Marcy's Agent #5 (voice) |
 | Bex Marsh als Agency Employee #5 / Female Tourist (voice) |
 | Peter S. Kim als Agency Employee #6 / Joon / Marcy's Agent #4 (voice) |
 | Gabriel Conte als Agency Employee #7 (voice) |
 | Jess Conte als Agency Employee #8 (voice) |
 | Rashawn Nadine Scott als Agency Employee #9 (voice) |
 | Stefania Spampinato als Agency Employee #10 / Italian Woman (voice) |
 | Nick Bruno als Agency Employee #11 / Pigeon Voice (voice) |
 | Troy Quane als Agency Employee #12 (voice) |
 | Eddie Mujica als Agency Accountant / Male Tourist (voice) |
| Emily Altman als Lead Agency Lab Tech / Scooter Girl (voice) |
 | Randy Trager als Terrance / Pigeon Voice (voice) |
| Christopher Campbell als Marcy's Agent #2 (voice) |
| Matthew J. Munn als Weapons Lab Soldier (voice) |
 | Kimberly Brooks als Lance's Car (voice) |
| Youn So als Soo-Min (voice) |
| Min-Hyuck Jang als Joon (voice) |
 | Randy Thom als Various Voices / Pigeon Voice (voice) |
 | Krizia Bajos als Receptionist (voice) |
 | Reggie De Leon als Weapons Lab Tech (voice) |
| Paolo Costantino Cenci als Scooter Guy (voice) |
| Casey M. Roberts als Launch Control Voice (voice) |
 | Daniel Booko als Additional Voice (voice) |
| Jen Cain als Additional Voice (voice) |
 | Oscar Camacho als Additional Voice (voice) |
 | David Chen als Additional Voice (voice) |
 | Johnny Gidcomb als Additional Voice (voice) |
 | Annie Gonzalez als Additional Voice (voice) |
 | Maya Goodwin als Additional Voice (voice) |
 | Danielle Hartnett als Additional Voice (voice) |
 | Marabina Jaimes als Additional Voice (voice) |
 | Masa Kanome als Additional Voice (voice) |
 | Ruth Zalduondo als Additional Voice (voice) |
 | Hideo Kimura als Additional Voice (voice) |
 | Dina Morrone als Additional Voice (voice) |
 | Dyana Ortelli als Additional Voice (voice) |
 | Arthur Ortiz als Additional Voice (voice) |
 | Chrystee Pharris als Additional Voice (voice) |
 | Ben Pronsky als Additional Voice (voice) |
 | Stan Sellers als Additional Voice (voice) |
 | Shane Sweet als Additional Voice (voice) |
| Michael Woodley als Additional Voice (voice) |
 | Vivian Yoon Lee als Additional Voice (voice) |
| Troy Quane | Director |
| Nick Bruno | Director |
| Lorry Ann Shea | Production Supervisor |
| Lyndon Ruddy | Storyboard Artist |
| John E. Hurst | Story Artist |
| Stephen Orsini | Animation |
| Warren Leonhardt | Storyboard Artist |
| Mike Smukavic | Storyboard Artist |
| Brock Boyts | Animation |
| Thom Roberts | Senior Animator |
| Eric Urquhart | Matte Painter |
| Paul Downs | Animation |
| Peter Lepeniotis | Animation |
| Bianca Siercke | Story Artist |
| Jason Fricchione | Production Supervisor |
| Yolanda Cheng | Technical Advisor |
| Jonathan Lin | Modeling |
| Bobby Pontillas | Character Designer |
| Julen Santiago | Animation |
| Trevor Young | Animation |
| Alex Angelis | Animation |
| Louaye Moulayess | Animation |
| Bryan Cox | Storyboard Artist |
| Sandeep Menon | Art Designer |
| Ian M. Burkard | Modelling Supervisor |
| Brent Le Blanc | Technical Advisor |
| Seth Boyden | Story Artist |
| Scott Farrell | Animation |
| Diana Rivera Vera | Production Coordinator |
| Michael J. Travers | Producer |
| Christian Kaplan | Casting |
| Vicki Saulls | Sculptor |
| Jen Hurler | Production Assistant |
| Dinis 'Dennis' Morais | Modeling |
| Keith Stichweh | Character Modelling Supervisor |
| Jennifer Brola | Production Design |
| Myke Bakich | Storyboard Artist |
| Jeff Call | Story Artist |
| Dave Vasquez | Animation |
| Julianne Jordan | Music Supervisor |
| Gina Zimmitti | Music Consultant |
| Haley Brooks | Production Assistant |
| Mike Safianoff | Animation |
| Dan Segarra | Animation |
| Tracy Priest | Production Design |
| Thomas Helman | Visual Effects |
| Stephen Dahler | Animation |
| Elena Ortego | Animation |
| Pedro Sanz | Senior Animator |
| Tansal Arnas | Production Supervisor |
| John E. Hurst | Storyboard Artist |
| Linda Brenon | Dialogue Editor |
| Cristin McKee | Animation |
| Justin Weg | Animation |
| Scott W. Edelman | Character Technical Supervisor |
| Misha Koplan | Character Technical Supervisor |
| José Manuel Fernández Oli | Character Designer |
| Brett Blake | Editor |
| Gregory St. Germain | Associate Editor |
| Theodore Shapiro | Original Music Composer |
| Randy Thom | Sound Re-Recording Mixer |
| Jeremy Bowker | Supervising Sound Editor |
| Randy Thom | Sound Designer |
| Lora Hirschberg | Sound Re-Recording Mixer |
| Jenno Topping | Producer |
| Daniela Kriston | Production Manager |
| Mike Smith | Storyboard Artist |
| Lloyd Taylor | Screenplay |
| Lucas Martell | Original Film Writer |
| Cindy Davis | Screenstory |
| Brad Copeland | Screenplay |
| Kori Adelson | Executive Producer |
| Chris Wedge | Executive Producer |
| Kristine Familletti | Associate Producer |
| Dana Lynn Bennett | Production Supervisor |
| Kyle Milardo | Associate Producer |
| Sumire Takamatsu | Associate Producer |
| Steve Barnett | Post Production Supervisor |
| Anthony Nisi | Associate Producer |
| Kyle Lawson | Associate Producer |
| Peter Chernin | Producer |
| Gina Grasso | Assistant Production Manager |
| Mark Jacyszyn | Associate Producer |
| Matthew O'Callaghan | Animation Supervisor |
| Michael Tanzillo | Visual Effects |
| Samson Neslund | Sound Effects Editor |
| Daniel Ceballos | Animation |
