 | Jack Black als JB |
 | Kyle Gass als KG |
 | JR Reed als Lee |
 | Ronnie James Dio als Dio |
 | Paul F. Tompkins als Open Mic Host |
 | Troy Gentile als Lil' JB |
 | Ned Bellamy als Security Guard |
 | Fred Armisen als Security Guard |
 | Kirk Ward als Car Chase Cop / Gang Leader |
 | Amy Poehler als Truck Stop Waitress |
 | Tim Robbins als The Stranger |
 | Dave Grohl als Satan |
 | Ben Stiller als Guitar Center Guy |
 | Lara Everly als Girl |
| Brittany Eldridge als Girl |
 | Melissa-Anne Davenport als Girl |
 | John Ennis als Gang Member |
 | Vincent Foster als Gang Member |
 | Jay Johnston als Gang Member |
 | Colin Hanks als Drunk Frat Dude |
 | Stephanie Erb als Al's Bar Waitress |
 | Amy Adams als Gorgeous Woman |
 | Milos Milicevic als Tattooed Biker |
| Molly Bryant als Ecstatic Woman |
 | Michael Rivkin als Poopy Guy |
 | Gregg Turkington als Stand Up Comic |
 | Patrick M. Walsh als Exploding Head Guy |
 | Bevin Kaye als Fainting Woman |
 | Evie Peck als KG's Mother |
| Mason Knight als Young KG |
 | Erik Walker als Bully |
 | Cynthia Ettinger als Betty Black |
 | Andrew Lewis Caldwell als Billy Black |
| Laura Milligan als Tarot Card Reader |
 | Jason Segel als Frat Boy #1 (uncredited) |
 | Meat Loaf als Bud Black (uncredited) |
 | John C. Reilly als Sasquatch (uncredited) |
| Kyle Gass | Producer |
| Stuart Cornfeld | Producer |
| Jack Black | Producer |
| David Rennie | Editor |
| Martin Whist | Production Design |
| Liam Lynch | Writer |
| Robert Brinkmann | Director of Photography |
| Jack Black | Writer |
| Kyle Gass | Writer |
| Maria Baker | Art Direction |
| Dayna Pink | Costume Designer |
| Rick Avery | Stunt Coordinator |
| Brian Avery | Stunt Coordinator |
| Jeanne McCarthy | Casting |
| Andrew Gross | Original Music Composer |
| Cale Boyter | Executive Producer |
| John Ashker | Stunt Double |
| Ben Stiller | Executive Producer |
| Richard Brener | Executive Producer |
| Toby Emmerich | Executive Producer |
| John King | Original Music Composer |
| Georgia Kacandes | Executive Producer |
| Tad Griffith | Stunt Double |
| Juel Bestrop | Casting |
| Liam Lynch | Director |
| Cole S. McKay | Stunt Double |
| Joni Avery | Stunts |
| Eliza Coleman | Stunts |
| Doug Coleman | Stunts |
| Jack Gill | Stunts |
| Rick Avery | Second Unit Director |
| Mic Rodgers | Stunts |
| Tim Trella | Stunts |
| Larry Rippenkroeger | Stunts |
| Danny Wynands | Stunts |
| Roger Richman | Stunts |
| Frank Torres | Stunts |
| Scotty Richards | Stunt Coordinator |
| Buck McDancer | Stunts |
| Ed McDermott II | Stunt Driver |
| Angelique Midthunder | Stunt Driver |
| Ian Quinn | Stunts |
| Rick Miller | Stunt Double |
| Terry Jackson | Stunts |
| Brian Machleit | Stunts |
| Steve Hart | Stunts |
| Michael Hugghins | Stunts |
| Jody Hart | Stunt Driver |
| Tom Elliott | Stunts |
| Sean Graham | Stunts |
| Robert Chapin | Stunts |
| Mike Avery | Stunts |
| Kevin Abercrombie | Stunts |
| Jeff Brockton | Stunts |
| Dean Bailey | Stunts |
| David D. Johnson | Visual Effects Supervisor |
| Lisa Avery | Stunts |
| Bill Church | Visual Effects |
| John Coats | Visual Effects |
| Brent M. Bowen | Visual Effects |
| David Bach | Supervising Sound Editor |
| Marc Glassman | Sound Effects Editor |
| Orada Jusatayanond | Sound Effects Editor |
| Clayton Weber | Sound Effects Editor |
| Derek Vanderhorst | Sound Effects Editor |
| Elmo Weber | Supervising Sound Editor |
| Andy Weder | Special Effects Coordinator |
| Mike Piccirillo | Art Department Coordinator |
| Heather Grierson | Second Assistant Director |
| Milos Milicevic | First Assistant Director |
| Velvet Andrews-Smith | Second Second Assistant Director |
| Ivan Kraljević | Second Second Assistant Director |
| Ralph Bertelle | Production Supervisor |
| Erik Holmberg | Executive In Charge Of Production |
| Kate Shorter | Makeup Department Head |
| Barney Burman | Makeup Designer |
| Linda D. Flowers | Hair Department Head |
| Merribelle Anderson | Key Hair Stylist |
| Ralis Kahn | Makeup Artist |
| Toni G | Special Effects Makeup Artist |
| Michael Marino | Special Effects Makeup Artist |
| Scott Stoddard | Special Effects Makeup Artist |
| Justin Stafford | Special Effects Makeup Artist |
| Mike Smithson | Special Effects Makeup Artist |
| Yeşim "Shimmy" Osman | Hairstylist |
| Don Diers | Set Decoration |
| Jack Black | Songs |
| Kyle Gass | Songs |
| Pamela Alch | Script Supervisor |
| Hope Slepak | Costume Supervisor |
| Jon Myers | Steadicam Operator |
| Zade Rosenthal | Still Photographer |
| David B. Nowell | Aerial Director of Photography |
| Paul Hughen | Second Unit Director of Photography |
| Michael FitzMaurice | Camera Operator |
| Thomas Vandermillen | First Assistant Camera |
