 | Casey Affleck als Robert Ford |
 | Brad Pitt als Jesse James |
 | Sam Rockwell als Charley Ford |
 | Paul Schneider als Dick Liddil |
 | Jeremy Renner als Wood Hite |
 | Garret Dillahunt als Ed Miller |
 | Sam Shepard als Frank James |
 | Mary-Louise Parker als Zee James |
 | Zooey Deschanel als Dorothy Evans |
 | Ted Levine als Sheriff Timberlake |
 | Michael Parks als Henry Craig |
 | Alison Elliott als Martha Bolton |
 | James Carville als Governor Crittenden |
 | Tom Aldredge als Major George Hite |
 | Hugh Ross als Narrator (voice) |
 | Brooklynn Proulx als Mary James |
 | Dustin Bollinger als Tim James |
 | Joel McNichol als Express Messenger |
 | James Defelice als Baggagemaster |
| J.C. Roberts als Engineer |
| Darrell Orydzuk als Ukrainian Train Passenger |
| Jonathan Erich Drachenberg als Young Train Passenger |
| Torben S. Hansen als Danish Train Passenger |
| Lauren Calvert als Ida |
| Kailin See als Sarah Hite |
| Jesse Frechette als Albert Ford |
 | Pat Healy als Wilbur Ford |
| Joel Duncan als Deputy |
| Stephanie Wahlstrom als Store Customer |
| Adam Arlukiewicz als Newsboy |
| Ian Ferrier als Photographer |
 | Michael J Rogers als Onlooker at Jesse's Death |
| Calvin Bliid als Small Boy at Jesse's Death |
 | Sarah Lind als Bob's Girlfriend |
 | Nick Cave als Bowery Saloon Singer |
 | Matthew Walker als Bowery Saloonkeeper |
 | Michael Copeman als Edward O'Kelly |
| Laryssa Yanchak als Ella Mae Waterson |
 | Anthony Harrison als Marshal Craig (uncredited) |
| Jules Daly | Producer |
| Ron Hansen | Novel |
| Nick Cave | Music |
| Andrew Dominik | Director |
| Roger Deakins | Director of Photography |
| Andrew Dominik | Screenplay |
| David Valdes | Producer |
| Dylan Tichenor | Editor |
| Warren Ellis | Music |
| Curtiss Clayton | Editor |
| Patricia Norris | Set Designer |
| Brad Pitt | Producer |
| Dede Gardner | Producer |
| Ridley Scott | Producer |
| Lisa Ellzey | Executive Producer |
| Brad Grey | Executive Producer |
| Tony Scott | Executive Producer |
| Ben Waisbren | Executive Producer |
| Patricia Norris | Costume Design |
| Mali Finn | Casting |
| Brian Leslie Parker | Unit Production Manager |
| Scott Robertson | First Assistant Director |
| Karen Sowiak | Second Assistant Director |
| Hamilton Sterling | Sound Effects Editor |
| Brent Woolsey | Stunt Coordinator |
| William H. Burton Sr. | Stunt Coordinator |
| Richard King | Sound Designer |
| Richard King | Supervising Sound Editor |
| Doug Hemphill | Sound Re-Recording Mixer |
| Ron Bartlett | Sound Re-Recording Mixer |
| Leslie Shatz | Sound Designer |
| Christopher S. Aud | Sound Designer |
| Kimberly Harris | ADR Editor |
| Linda Yeaney | First Assistant Sound Editor |
| Andrew Bock | First Assistant Sound Editor |
| Michael Magill | Dialogue Editor |
| Hugo Weng | Dialogue Editor |
| Allen Hartz | Dialogue Editor |
| Michael W. Mitchell | Sound Effects Editor |
| Michael Babcock | Sound Effects Editor |
| Christopher Flick | Foley Supervisor |
| Michael Dressel | Foley Editor |
| Jonathan Klein | Foley Editor |
| Mark Pappas | Foley Editor |
| Sarah Monat | Foley Artist |
| Robin Harlan | Foley Artist |
| Randy Singer | Foley Mixer |
| John P. Fasal | ADR Mixer |
| Jacob Riehle | Assistant Sound Editor |
| Will Kaplan | Music Editor |
| Jonathan Karp | Music Editor |
| Martin Keough | Chief Lighting Technician |
| Mike Gould | Assistant Chief Lighting Technician |
| Gordon Schmidt | Rigging Gaffer |
| Rick D. Schmidt | Key Grip |
| Bruce Hamme | Dolly Grip |
| Mo Henry | Negative Cutter |
| Guy Bews | Stunts |
| Chad Cosgrave | Stunts |
| Colt Cosgrave | Stunts |
| Joe Dodds | Stunts |
| Jordan Dodds | Stunts |
| Bret Edge | Stunts |
| Lyle W. Edge | Stunts |
| Tom Eirikson | Stunts |
| Jim Finkbeiner | Stunts |
| Wacey Finkbeiner | Stunts |
| Dale Gibson | Stunts |
| Corry Glass | Stunts |
| Jason Glass | Stunts |
| Kristy Glass-Suitor | Stunts |
| Reg Glass | Stunts |
| Tom Glass | Stunts |
| Alex Green | Stunts |
| Dennis Hambling | Stunts |
| Randy Hambling | Stunts |
| Dave Hospes | Stunts |
| Michael Langlois | Stunts |
| Terrance Leigh | Stunts |
| Jacqueline Loewen | Stunts |
| Shane Pollitt | Stunts |
| Jim Randle | Stunts |
| Blake Schlosser | Stunts |
| Greg Schlosser | Stunts |
| John Scott | Stunts |
| Rick Skene | Stunts |
| Sean Skene | Stunts |
| Jodi Terhoch | Stunts |
| Jesse Thompson | Stunts |
| Kyle Thomson | Stunts |
| Russ Wideman | Stunts |
| Ron Hansen | Associate Producer |
| Jackie Lind | Locale Casting Director |
| Deb Green | Locale Casting Director |
| Troy Sizemore | Art Direction |
| Kimberley Zaharko | Assistant Art Director |
| Jackie Bagley | Assistant Art Director |
| Janice Blackie-Goodine | Set Decoration |
| Sean Blackie | Assistant Set Decoration |
| Alfred A. Arndt | Construction Coordinator |
| Roger Deakins | "A" Camera Operator |
| Andy Harris | First Assistant "A" Camera |
| David Lourie | Second Assistant "A" Camera |
| Susan Strembitsky | Second Assistant "A" Camera |
| Damon Moreau | Steadicam Operator |
| Kimberly French | Still Photographer |
| Rob Doak | Video Assist Operator |
| Nancy Joy McDonald | Script Supervisor |
| Bruce Carwardine | Production Sound Mixer |
| Markus Wade | Boom Operator |
| Geo Major | Boom Operator |
| David Dresher | Post Production Supervisor |
| Peter McNulty | Associate Editor |
| Hugh Ross | First Assistant Editor |
| Alex Hepburn | Assistant Editor |
| Marie Gaerlan | Assistant Editor |
| John Paul Horstmann | Assistant Editor |
| Chris Speers | Best Boy Grip |
| Dean Goodine | Property Master |
| Shelly Goldsack | Assistant Property Master |
| Johnny Jones | Assistant Property Master |
| James Paradis | Special Effects Supervisor |
| Maurice Routly | Special Effects Coordinator |
| Lizzie McGovern | Assistant Costume Designer |
| Kelly Fraser | Costume Supervisor |
| Gail Kennedy | Makeup Department Head |
| Jean Ann Black | Makeup Artist |
| Rochelle Pomerleau | Makeup Artist |
| Christien Tinsley | Special Effects Makeup Artist |
| Iloe Flewelling | Key Hair Stylist |
| Chris Harrison-Glimsdale | Hairstylist |
| Jill Christensen | Production Office Coordinator |
| Nicole Florian | Production Office Coordinator |
| David Valdes | Unit Production Manager |
| Dorothy Precious | Production Accountant |
| Carol Rothel | Assistant Accountant |
| Raluca Sheridan | Assistant Accountant |
| Rino Pace | Location Manager |
| Robert Hilton | Location Manager |
| Jay St. Louis | Assistant Location Manager |
| Stuart Becker | Assistant Location Manager |
| Lisa Jemus | Third Assistant Director |
| Louise Mackiewicz | Extras Casting |
| Janet Powers | Extras Casting |
| Lauren Bass | Casting Associate |
| Elizabeth Shoai | Casting Assistant |
| Lee Anne Muldoon | Unit Publicist |
| Craig Humphries | Graphic Designer |
| Grant Van Der Slagt | Set Designer |
| Marilyn Humphries | Set Designer |
| Brad Milburn | Set Designer |
| Gordon White | Set Designer |
| Terry Gunvordahl | Set Designer |
| Michael Madden | Set Designer |
| Al Berg | Storyboard Artist |
| Wendy Dobson | Art Department Coordinator |
| Amber Humphries | Set Dresser |
| Laura Cuthill | Set Dresser |
| Jack Lowen | Set Dresser |
| Marlis Wilson | Set Dresser |
| Jay Benoliel | Set Dresser |
| Stacey Gooch | Set Dresser |
| Coleman Robinson | Transportation Coordinator |
| Dean Robinson | Transportation Captain |
| Ray Breckenridge | Transportation Co-Captain |
| James Leake | Title Designer |
| Terry Hager | Color Timer |
| Michael Hatzer | Digital Intermediate Colorist |
| Michael Kennedy | Digital Intermediate Producer |
| Devon Miller | Digital Intermediate Editor |
| Sophie Leclerc | Visual Effects Producer |
| Brandy Hagborg | Location Coordinator |
| Richard Hoover | Production Design |
| Patricia Norris | Production Design |
