 | Michael Parks als Adam |
 | Ulla Bergryd als Eve |
 | Richard Harris als Cain |
 | John Huston als Noah |
 | Stephen Boyd als Nimrod |
 | George C. Scott als Abraham |
 | Ava Gardner als Sarah |
 | Peter O'Toole als The Three Angels |
 | Zoe Sallis als Hagar |
 | Gabriele Ferzetti als Lot |
 | Eleonora Rossi Drago als Lot's wife |
 | Franco Nero als Abel |
 | Pupella Maggio als Noah's wife |
 | Robert Rietti als Abraham's Steward |
 | Peter Heinze als Ham |
| Roger Beaumont |
| Gianluigi Crescenzi |
 | Maria Grazia Spina als Lot's daughter # 2 |
 | Angelo Boscariol als Shem |
 | Claudie Lange als Nimrod's wife |
 | Anna Orso als Shem's wife |
 | Adriana Ambesi als Lot's daughter # 1 |
| Eric Leutzinger als Japhet |
| Michael Steinpichler |
 | Gabriella Pallotta als Ham's wife |
| Alberto Lucantoni als Isaac |
| Rossana Di Rocco als Japhet's wife |
| Luciano Conversi als Ismael |
 | Giovanna Galletti als Sinful Woman |
 | Lars Bloch als Archangel (uncredited) |
| Flavio Bennati als Serpent (uncredited) |
 | Salvatore Billa als Abraham's Follower (uncredited) |
 | Giovanni Di Benedetto als Nimrod's Man (uncredited) |
 | Ivan Rassimov als Dignitary at Babylon (uncredited) |
 | Romano Moraschini als Sinful Man (uncredited) |
 | Veriano Ginesi als Sinful Man (uncredited) |
 | Alberigo Donadeo als Sinful Man (uncredited) |
 | Amerigo Santarelli als Sinful Man (uncredited) |
 | Mimmo Poli als Sodomite (uncredited) |
| Fred Coplan als Abraham's Follower (uncredited) |
| Dino De Laurentiis | Producer |
| Giuseppe Rotunno | Director of Photography |
| John Huston | Director |
| Ralph Kemplen | Editor |
| Enzo Eusepi | Set Decoration |
| Maria De Matteis | Costume Design |
| Guidarino Guidi | Casting |
| Mario Chiari | Art Direction |
| Toshirō Mayuzumi | Original Music Composer |
| Christopher Fry | Screenplay |
| Orson Welles | Additional Writing |
| Mario Soldati | Additional Writing |
| Jonathan Griffin | Writers' Assistant |
| Ivo Perilli | Writers' Assistant |
| Vittorio Bonicelli | Writers' Assistant |
| Luigi Luraschi | Associate Producer |
| Ennio Morricone | Additional Music |
| Alberto Gallitti | Additional Editing |
| Alberto De Rossi | Makeup Supervisor |
| Elda Magnanti | Hairdresser |
| Sandro Melaranci | Makeup Artist |
| Bruno Todini | Production Manager |
| Linwood G. Dunn | Special Effects |
| Yvonne Axeworthy | Script Editor |
| Murray Spivack | Recording Supervision |
| Franco Ferrara | Conductor |
| Gilbert D. Marchant | Music Editor |
| Goffredo Petrassi | Music Consultant |
| Eunice Mountjoy | Assistant Editor |
| Virgilio Ponti | Stunts |
| Giuseppe Di Biase | First Assistant Camera |
| Franco Nero | Still Photographer |
| Donald C. Rogers | Second Unit Director of Photography |
| Piero Servo | Assistant Camera |
| Giuseppe Maccari | Camera Operator |
| Vladimiro Salvatori | Grip |
| Cristo Verrillo | Electrician |
| Carlo Rambaldi | Special Effects |
| Carlo De Marchis | Special Effects Assistant |
| Augie Lohman | Special Effects |
| Zeus Ianiro | Special Effects |
| Basil Fenton-Smith | Sound Recordist |
| Leslie Hodgson | Sound Editor |
| Fred Hynes | Recording Supervision |
| John Blunk | Sound Effects Editor |
| Wayne Fury | Sound Effects Editor |
| Marvin Walowitz | Sound Effects Editor |
| James D. Young | Assistant Sound Editor |
| Piero De Luca | Production Manager |
| Ottavio Oppo | Assistant Director |
| Vana Caruso | Assistant Director |
| Ernst Haas | Second Unit Director |
| Enzo Eusepi | Set Dresser |
| Aldo Puccini | Set Designer |
| Italo Tomassi | Painter |
| Luciano Puccini | Assistant Set Decoration |
| Tani | Property Master |
| Mario Scisci | Set Designer |
| Pasquale Romano | Assistant Art Director |
| Stephen B. Grimes | Assistant Art Director |
| Katherine Dunham | Choreographer |
| Fred Sidewater | Producer's Assistant |
| Ralph B. Serpe | Producer's Assistant |
| Giorgio Morra | Production Assistant |
| Gladys Hill | Assistant Director Trainee |
| Salvatore Garofalo | Consulting Producer |
| W.M. Merchant | Consulting Producer |
| Angelo Lombardi | Consulting Producer |
| Orson Welles | Scenario Writer |
